LOCUS BC015782 3266 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens heterogeneous nuclear ribonucleoprotein U (scaffold
attachment factor A), mRNA (cDNA clone MGC:23593 IMAGE:4857112),
complete cds.
ACCESSION BC015782
VERSION BC015782.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3266)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3266)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: e Column: 9.
FEATURES Location/Qualifiers
source 1..3266
/db_xref="H-InvDB:HIT000037320"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23593 IMAGE:4857112"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3266
/gene="HNRPU"
/gene_synonym="HNRNPU"
/gene_synonym="SAF-A"
/gene_synonym="U21.1"
/db_xref="GeneID:3192"
/db_xref="MIM:602869"
CDS 5..2173
/gene="HNRPU"
/gene_synonym="HNRNPU"
/gene_synonym="SAF-A"
/gene_synonym="U21.1"
/codon_start=1
/product="HNRPU protein"
/protein_id="AAH15782.1"
/db_xref="GeneID:3192"
/db_xref="MIM:602869"
/translation="MELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGD
EEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQ
GQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEE
NKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWA
GGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKE
VLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKK
DCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLN
TLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDE
DYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQY
KEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNR
GGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQN
FRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY"
misc_feature 734..1084
/gene="HNRPU"
/gene_synonym="HNRNPU"
/gene_synonym="SAF-A"
/gene_synonym="U21.1"
/note="SPRY; Region: SPRY domain. SPRY Domain is named
from SPla and the RYanodine Receptor. Domain of unknown
function. Distant homologues are domains in
butyrophilin/marenostrin/pyrin homologues"
/db_xref="CDD:pfam00622"
misc_feature 1190..1642
/gene="HNRPU"
/gene_synonym="HNRNPU"
/gene_synonym="SAF-A"
/gene_synonym="U21.1"
/note="COG4639; Region: COG4639, Predicted kinase [General
function prediction only]"
/db_xref="CDD:COG4639"
BASE COUNT 1030 a 581 c 831 g 824 t
ORIGIN
1 ccagatggag ctaggagagg agaacggggc cgcgggggcg gccgactcgg gcccgatgga
61 ggaggaggag gccgcctcgg aagacgagaa cggcgacgat cagggtttcc aggaagggga
121 agatgagctc ggggacgaag aggaaggcgc gggcgacgag aacgggcacg gggagcagca
181 gcctcaaccg ccggcgacgc agcagcaaca gccccaacag cagcgcgggg ccgccaagga
241 ggccgcgggg aagagcagcg gccccacctc gctgttcgcg gtgacggtgg cgccgcccgg
301 ggcgaggcag ggccagcagc aggcgggagg taagaagaag gcggaaggcg gcggaggcgg
361 cggtcgcccc ggggctccgg cggcggggga cggcaaaaca gaacagaaag gcggagataa
421 aaagaggggt gttaaaagac cacgagaaga tcatggccgt ggatattttg agtacattga
481 agagaacaag tatagcagag ccaaatctcc tcagccacct gttgaagaag aagatgaaca
541 cttcgatgac acagtggttt gtcttgatac ttataattgt gatctacatt ttaaaatatc
601 aagagatcgt ctcagtgctt cttcccttac aatggagagt tttgcttttc tttgggctgg
661 aggaagagca tcctatggtg tgtcaaaagg caaagtgtgt tttgagatga aggttacaga
721 gaagatccca gtaaggcatt tatatacaaa agatattgac atacatgaag ttcgtattgg
781 ctggtcacta actacaagtg gaatgttact tggtgaagaa gaattttctt atgggtattc
841 tctaaaagga ataaaaacat gcaactgtga gactgaagat tatggagaaa agtttgatga
901 aaatgatgtg attacatgtt ttgctaactt tgaaagtgat gaagtagaac tctcgtatgc
961 taagaatgga caagatcttg gcgttgcctt caaaatcagt aaggaagttc ttgctggacg
1021 gccactgttc ccgcatgttc tctgccacaa ctgtgcagtt gaatttaatt ttggtcagaa
1081 ggaaaagcca tattttccaa tacctgaaga gtatactttc atccagaacg tccccttaga
1141 ggatcgagtt agaggaccaa aggggcctga agagaagaaa gattgtgaag ttgtgatgat
1201 gattggcttg ccaggagctg gaaaaactac ctgggttact aaacatgcag cagaaaatcc
1261 agggaaatat aacattcttg gcacaaatac tattatggat aagatgatgg tggcaggttt
1321 taagaagcaa atggcagata ctggaaaact gaacacactg ttgcagagag ccccccagtg
1381 tcttgggaaa tttattgaga ttgctgcccg aaagaagcga aattttattc tggatcagac
1441 aaatgtgtct gctgctgccc agaggagaaa aatgtgcctg tttgcaggct tccagcgaaa
1501 agctgttgta gtttgcccaa aagatgaaga ctataagcaa agaacacaga agaaagcaga
1561 agtagagggg aaagacctac cagaacatgc ggtcctcaaa atgaaaggaa actttaccct
1621 cccagaggta gctgagtgct ttgatgaaat aacctatgtt gaacttcaga aggaagaagc
1681 ccaaaaactc ttggagcaat ataaggaaga aagcaaaaag gctcttccac cagaaaagaa
1741 acagaacact ggctcaaaga aaagcaataa aaataagagt ggcaagaacc agtttaacag
1801 aggtggtggc catagaggac gtggaggatt caatatgcgt ggtggaaatt tcagaggagg
1861 agcccctggg aatcgtggcg gatataatag gaggggcaac atgccacaga gaggtggtgg
1921 cggtggagga agtggtggaa tcggctatcc ataccctcgt gcccctgttt ttcctggccg
1981 tggtagttac tcaaacagag ggaactacaa cagaggtgga atgcccaaca gagggaacta
2041 caaccagaac ttcagaggac gaggaaacaa tcgtggctac aaaaatcaat ctcagggcta
2101 caaccagtgg cagcagggtc aattctgggg tcagaagcca tggagtcagc attatcacca
2161 aggatattat tgaataccca aataaaacga actgatacat atttctccaa aaccttcaca
2221 agaagtcgac tgttttcttt agtaggctaa ctttttaaac attccacaag aggaagtgcc
2281 tgcgggttcc ttttttagaa gctttgtggg ttgatttttt ttcttttctt ttttgtacat
2341 ttttaattgc agtttaaaag tgaatcgtaa gagaacctca gcattgtgca cgataagaga
2401 atgtgtcagt atttcagggt tctacatttt atctgtaaaa tgtgactttt tttttttttt
2461 atcacaacag aagtaaaatg ttgctttgta cctggtgtct tttattaaga atttactccc
2521 cccatttctc acagagaata acagtcggga gtcattgtca caatataata gaaatgttag
2581 caaccagatt catgtaagga ctaagtggtc ctcatgaatt gcattaagac tctgtactgc
2641 tcatattaca ctccatcctc tctgtagttt gctgggtagt ggagggggta agctaaatca
2701 tagtttctga caataactgg gaaggttttt tcttaaaata acaatggaat tggtataatt
2761 gggattgaaa actaaaactt ggaactaaga tagagaagat ggagtgtatg tagaagggct
2821 gttaaaaatg taaaacttgg ttgcattatt tgtggaggct caaacttgtg aaggttaata
2881 ccataatttt tccatttgtt ctgcattttg attctgaaaa gaaagctggc tttgcccatt
2941 tcttattaaa aaaacttgtt gtaaatccag ttgtctaatg ggatctatat gaagttagcc
3001 atgtctgtat gcccttctcc cacaaaatac tgtataacta gtgtgcttgt agtagttaac
3061 tccaccatct ttgtaagcta atgaaattgt gagtcaccca tttatatctt aatttttaat
3121 catgtcagtt cttgaatggg tatctcctta gcctgctgat ttctttttct ttctaaagaa
3181 agtgggtgga gaaattaatt tagacgtttg tttgcaataa aaagaattca ttttaaaaaa
3241 aaaaaaaaaa aaaaaaaaaa aaaaaa
//