LOCUS BC015739 884 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens granzyme A (granzyme 1, cytotoxic
T-lymphocyte-associated serine esterase 3), mRNA (cDNA clone
MGC:23007 IMAGE:4849202), complete cds.
ACCESSION BC015739
VERSION BC015739.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 884)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 884)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Daniel McVicar, DBS/NCI
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: a Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6996012.
FEATURES Location/Qualifiers
source 1..884
/db_xref="H-InvDB:HIT000037287"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23007 IMAGE:4849202"
/tissue_type="Blood, natural killer cell"
/clone_lib="NIH_MGC_106"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..884
/gene="GZMA"
/db_xref="GeneID:3001"
/db_xref="HGNC:HGNC:4708"
/db_xref="MIM:140050"
CDS 9..797
/gene="GZMA"
/codon_start=1
/product="granzyme A (granzyme 1, cytotoxic
T-lymphocyte-associated serine esterase 3)"
/protein_id="AAH15739.1"
/db_xref="GeneID:3001"
/db_xref="HGNC:HGNC:4708"
/db_xref="MIM:140050"
/translation="MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMV
LLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFP
YPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSA
SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLC
EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV"
BASE COUNT 274 a 183 c 188 g 239 t
ORIGIN
1 cagccacaat gaggaactcc tatagatttc tggcatcctc tctctcagtt gtcgtttctc
61 tcctgctaat tcctgaagat gtctgtgaaa aaattattgg aggaaatgaa gtaactcctc
121 attcaagacc ctacatggtc ctacttagtc ttgacagaaa aaccatctgt gctggggctt
181 tgattgcaaa agactgggtg ttgactgcag ctcactgtaa cttgaacaaa aggtcccagg
241 tcattcttgg ggctcactca ataaccaggg aagagccaac aaaacagata atgcttgtta
301 agaaagagtt tccctatcca tgctatgacc cagccacacg cgaaggtgac cttaaacttt
361 tacagctgac ggaaaaagca aaaattaaca aatatgtgac tatccttcat ctacctaaaa
421 agggggatga tgtgaaacca ggaaccatgt gccaagttgc agggtggggc aggactcaca
481 atagtgcatc ttggtccgat actctgagag aagtcaatat caccatcata gacagaaaag
541 tctgcaatga tcgaaatcac tataatttta accctgtgat tggaatgaat atggtttgtg
601 ctggaagcct ccgaggtgga agagactcgt gcaatggaga ttctggaagc cctttgttgt
661 gcgagggtgt tttccgaggg gtcacttcct ttggccttga aaataaatgc ggagaccctc
721 gtgggcctgg tgtctatatt cttctctcaa agaaacacct caactggata attatgacta
781 tcaagggagc agtttaaata accgtttcct ttcatttact gtggcttctt aatcttttca
841 caaataaaat caatttgcat gactgtaaaa aaaaaaaaaa aaaa
//