LOCUS BC014992 1678 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 4, mRNA (cDNA clone MGC:23251
IMAGE:4866432), complete cds.
ACCESSION BC014992
VERSION BC014992.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1678)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1678)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: j Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361301.
FEATURES Location/Qualifiers
source 1..1678
/db_xref="H-InvDB:HIT000036951"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23251 IMAGE:4866432"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1678
/gene="SERPINA4"
/gene_synonym="KAL"
/gene_synonym="kallistatin"
/gene_synonym="KLST"
/gene_synonym="KST"
/db_xref="GeneID:5267"
/db_xref="HGNC:HGNC:8948"
/db_xref="MIM:147935"
CDS 67..1350
/gene="SERPINA4"
/gene_synonym="KAL"
/gene_synonym="kallistatin"
/gene_synonym="KLST"
/gene_synonym="KST"
/codon_start=1
/product="serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 4"
/protein_id="AAH14992.1"
/db_xref="GeneID:5267"
/db_xref="HGNC:HGNC:8948"
/db_xref="MIM:147935"
/translation="MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGE
GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQIL
EGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTM
AVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKAL
WEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATV
FFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILP
RLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT
NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP"
BASE COUNT 399 a 466 c 443 g 370 t
ORIGIN
1 cagagctgag acagccaccc agggggtcca ctccaggaca gactgtgccg cctgagagtg
61 cagaggatgc atcttatcga ctacctgctc ctcctgctgg ttggactact ggccctttct
121 catggccagc tgcacgttga gcatgatggt gagagttgca gtaacagctc ccaccagcag
181 attctggaga caggtgaggg ctcccccagc ctcaagatag cccctgccaa tgctgacttt
241 gccttccgct tctactacct gatcgcttcg gagaccccgg ggaagaacat ctttttctcc
301 ccgctgagca tctcggcggc ctacgccatg ctttccctgg gggcctgctc acacagccgc
361 agccagatcc ttgagggcct gggcttcaac ctcaccgagc tgtctgagtc cgatgtccat
421 aggggcttcc agcacctcct gcacactctc aacctccccg gccatgggct ggaaacacgc
481 gtgggcagtg ctctgttcct gagccacaac ctgaagttcc ttgcaaaatt cctgaatgac
541 accatggccg tctatgaggc taaactcttc cacaccaact tctacgacac tgtgggcaca
601 atccagctta tcaacgacca cgtcaagaag gaaactcgag ggaagattgt ggatttggtc
661 agtgagctca agaaggacgt cttgatggtg ctggtgaatt acatttactt caaagccctg
721 tgggagaaac cattcatttc ctcaaggacc actcccaaag acttttatgt tgatgagaac
781 acaacagtcc gggtgcccat gatgctgcag gaccaggagc atcactggta tcttcatgac
841 agatacttgc cctgctcggt gctacggatg gattacaaag gagacgcaac cgtgtttttc
901 attctcccta accaaggcaa aatgagggag attgaagagg ttctgactcc agagatgcta
961 atgaggtgga acaacttgtt gcggaagagg aatttttaca agaagctaga gttgcatctt
1021 cccaagttct ccatttctgg ctcctatgta ttagatcaga ttttgcccag gctgggcttc
1081 acggatctgt tctccaagtg ggctgactta tccggcatca ccaaacagca aaaactggag
1141 gcatccaaaa gtttccacaa ggccaccttg gacgtggatg aggctggcac cgaggctgca
1201 gcagccacca gcttcgcgat caaattcttc tctgcccaga ccaatcgcca catcctgcga
1261 ttcaaccggc ccttccttgt ggtgatcttt tccaccagca cccagagtgt cctctttctg
1321 ggcaaggtcg tcgaccccac gaaaccatag ccctcccagg gctgctcatc tgttccaagc
1381 aggaggatgt ggcaggggag ggctgggagt gagtagctct gtgtttagag ttggggacaa
1441 ggatgacacc gaaggtccag gagtccagga cagcaggtgc tggccggtgg ggagcgggga
1501 ggggcactga gatgggcagg gcctggacat tccacaccct ggtgctgtgc agcctctggc
1561 agagcatccg acctcttgga gcaagtttct gcctctggaa agggggcggg cccttttcac
1621 aacaggctgg ttgtaccgag taaacaacac gatgccatga aaaaaaaaaa aaaaaaaa
//