LOCUS BC014973 2455 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens Smith-Magenis syndrome chromosome region, candidate 7,
mRNA (cDNA clone MGC:23130 IMAGE:4859126), complete cds.
ACCESSION BC014973
VERSION BC014973.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2455)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2455)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: f Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22538489.
FEATURES Location/Qualifiers
source 1..2455
/db_xref="H-InvDB:HIT000036934"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23130 IMAGE:4859126"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2455
/gene="SMCR7"
/gene_synonym="MGC23130"
/db_xref="GeneID:125170"
/db_xref="HGNC:HGNC:17920"
CDS 60..1424
/gene="SMCR7"
/gene_synonym="MGC23130"
/codon_start=1
/product="Smith-Magenis syndrome chromosome region,
candidate 7"
/protein_id="AAH14973.1"
/db_xref="GeneID:125170"
/db_xref="HGNC:HGNC:17920"
/translation="MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIAT
LAVKRFIDRATSPRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSA
PEGPAETDPEVTPQLSSPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALEL
QAYFRSKFPELPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVAR
DPRCWAVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLG
CLIRPSMASEELLLEVQHERLELTVAVLVAVPGVDADDRLLLAWPLEGLAGNLWLQDL
YPVEAARLRALDDHDAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDW
TEEALGERFLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEP
EGLL"
BASE COUNT 440 a 719 c 777 g 519 t
ORIGIN
1 ctgaggcctg cgcgaccccg ccagagatgg ggctgagtcc caatttagac aggcagacca
61 tggcagagtt ctcccagaaa cgggggaagc ggcgtagcga cgaagggctg ggcagcatgg
121 tggacttcct cctggccaat gcccgcctgg tgctgggcgt gggcggggct gctgtgctgg
181 gcattgccac cctggccgtg aagcggttca ttgacagggc cactagcccg cgggatgagg
241 atgacaccaa ggcagacagc tggaaggaac tgagcctgct caaggccaca ccacacctgc
301 agccccggcc tccacctgct gcccttagcc agccagtgtt gcccttggcc ccctcgtcgt
361 ctgccccaga agggcctgca gaaactgatc ctgaggtgac accacagctc agctccccag
421 caccgctgtg tctgacactg caggagaggc tgctggcctt cgagcgggac cgtgtgacca
481 tcccagcagc ccaggtggct ttggccaaac agctggctgg cgacatcgcc ctggagctgc
541 aggcctactt tcggagcaag ttcccggaac tgccctttgg ggcattcgtg cctggggggc
601 cgctctacga cgggctgcag gcgggggctg cggaccatgt gcgtctcctg gtgccactgg
661 tgctggagcc gggcctgtgg agcctggtgc cgggcgtgga cactgtggcg agggaccctc
721 gctgctgggc cgtgcgcagg acgcagcttg agttctgccc ccgtgggagc agcccctggg
781 accgcttcct ggtcgggggc tacctctcct cccgcgtcct gctggagcta ctccgcaagg
841 cgctggctgc ctctgtcaac tggccggcca ttggcagcct tctcgggtgc ctgatccggc
901 ccagcatggc ctcggaggag ctgctgctcg aggtgcagca cgaacgcctg gagctcactg
961 tggctgtgct tgtggcagtc cctggggtcg atgctgacga ccgcctcctc ttggcctggc
1021 ccctggaggg gctggcgggg aacctctggc tgcaggacct gtatccagtg gaggctgcta
1081 ggctgcgagc cctggacgac catgacgctg ggactcgccg gcggctgctg ctgctgctgt
1141 gtgctgtctg ccgtggttgc tcggctctgg ggcagctagg ccggggtcac ctgacccagg
1201 tggtcctgcg tctgggggag gacaacgtgg attggacgga ggaggccttg ggtgagcgct
1261 tcctgcaagc cctggagctg ctcatcggca gcctggagca ggccagcctg ccctgccact
1321 tcaaccccag cgtgaacctc ttcagcagct tgcgtgagga ggagattgac gacattggct
1381 atgcgctata cagtggccta caggagcccg aggggctgct ctaggtgggt ggaaacgggt
1441 ggttgccatg ttttctaatg ctggggagct gcacccacct cccttccagg gatttgaata
1501 gtggtttttc tctagctttt tgccagaaca aaggagggta cattacttaa acccagggca
1561 tcaggatgtg cttgggctat ggtggccata aaccctgagc ccagagagct tgggtcactg
1621 tcacctgagt gcagctgggc tgcctcaggc agcttggagt gccagccatt cctgcaagca
1681 ccgtttcagc tcttggggcc aaccccagga cctttggctc tgtccatcac cagcaaccaa
1741 tccaccaaca gaatgtggtt tctgccatcc tgggcagaag ctgaaggcca gcttcacatt
1801 tctgctgaga gaaggtgact taacgccttt tccggcccta gctccaggcg ttttgaggcg
1861 tctggtgcct gatggtaggt atggtgtgtt tgttctgtcc cccaggggct ggagtcacct
1921 ggtgcccctg aaggacagat ttttggctgt taaaggatgg cattttcctg ctgtcttctg
1981 tgcgtttagt tttcttgctg agcgggagct cagtatgact tgccacccac ctgatacctc
2041 agggcaaggc cctttttccc tccagccagg tgagtgtttt cttcaggcag ctgagggtcc
2101 tgggggagct gaggctctgt gctgcacccc cagcccacag ctggggcatc tcactggagc
2161 tgttccaggc cccactggag agcagaggac ctgatccccc actagagagg tccggtgtgc
2221 acagccggcc tcccagtgtg ccaaaatgaa ctgctctcag ctgatggctg tattctgact
2281 ttgaagcctg ttaagaggta gcaagggggc tagaggaggg agattccacc tcccctccca
2341 agtgaccctc ctgcctctgg tatccttcct tttgaaacga agctcagctt cgaagatgtg
2401 aacaagaata aaaggaaaaa attctaatgt atatataaaa aaaaaaaaaa aaaaa
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