LOCUS BC014972 1472 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interleukin 2 receptor, gamma (severe combined
immunodeficiency), mRNA (cDNA clone MGC:23116 IMAGE:4878734),
complete cds.
ACCESSION BC014972
VERSION BC014972.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1472)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1472)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: n Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557881.
FEATURES Location/Qualifiers
source 1..1472
/db_xref="H-InvDB:HIT000036933"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23116 IMAGE:4878734"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1472
/gene="IL2RG"
/gene_synonym="CD132"
/gene_synonym="SCIDX"
/db_xref="GeneID:3561"
/db_xref="HGNC:HGNC:6010"
/db_xref="MIM:308380"
CDS 5..1114
/gene="IL2RG"
/gene_synonym="CD132"
/gene_synonym="SCIDX"
/codon_start=1
/product="interleukin 2 receptor, gamma (severe combined
immunodeficiency)"
/protein_id="AAH14972.1"
/db_xref="GeneID:3561"
/db_xref="HGNC:HGNC:6010"
/db_xref="MIM:308380"
/translation="MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTT
MPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKC
SHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENL
TLHKLSESQLELNWNNRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKR
YTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISL
LCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSE
IPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET"
BASE COUNT 373 a 421 c 309 g 369 t
ORIGIN
1 cgccatgttg aagccatcat taccattcac atccctctta ttcctgcagc tgcccctgct
61 gggagtgggg ctgaacacga caattctgac gcccaatggg aatgaagaca ccacagctga
121 tttcttcctg accactatgc ccactgactc cctcagtgtt tccactctgc ccctcccaga
181 ggttcagtgt tttgtgttca atgtcgagta catgaattgc acttggaaca gcagctctga
241 gccccagcct accaacctca ctctgcatta ttggtacaag aactcggata atgataaagt
301 ccagaagtgc agccactatc tattctctga agaaatcact tctggctgtc agttgcaaaa
361 aaaggagatc cacctctacc aaacatttgt tgttcagctc caggacccac gggaacccag
421 gagacaggcc acacagatgc taaaactgca gaatctggtg atcccctggg ctccagagaa
481 cctaacactt cacaaactga gtgaatccca gctagaactg aactggaaca acagattctt
541 gaaccactgt ttggagcact tggtgcagta ccggactgac tgggaccaca gctggactga
601 acaatcagtg gattatagac ataagttctc cttgcctagt gtggatgggc agaaacgcta
661 cacgtttcgt gttcggagcc gctttaaccc actctgtgga agtgctcagc attggagtga
721 atggagccac ccaatccact gggggagcaa tacttcaaaa gagaatcctt tcctgtttgc
781 attggaagcc gtggttatct ctgttggctc catgggattg attatcagcc ttctctgtgt
841 gtatttctgg ctggaacgga cgatgccccg aattcccacc ctgaagaacc tagaggatct
901 tgttactgaa taccacggga acttttcggc ctggagtggt gtgtctaagg gactggctga
961 gagtctgcag ccagactaca gtgaacgact ctgcctcgtc agtgagattc ccccaaaagg
1021 aggggccctt ggggaggggc ctggggcctc cccatgcaac cagcatagcc cctactgggc
1081 ccccccatgt tacaccctaa agcctgaaac ctgaacccca atcctctgac agaagaaccc
1141 cagggtcctg tagccctaag tggtactaac tttccttcat tcaacccacc tgcgtctcat
1201 actcacctca ccccactgtg gctgatttgg aattttgtgc ccccatgtaa gcaccccttc
1261 atttggcatt ccccacttga gaattaccct tttgccccga acatgttttt cttctccctc
1321 agtctggccc ttccttttcg caggattctt cctccctccc tctttccctc ccttcctctt
1381 tccatctacc ctccgattgt tcctgaaccg atgagaaata aagtttctgt tgataatcat
1441 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
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