LOCUS BC014852 1780 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interferon regulatory factor 6, mRNA (cDNA clone
MGC:5122 IMAGE:3449699), complete cds.
ACCESSION BC014852
VERSION BC014852.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1780)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1780)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: p Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24497623.
FEATURES Location/Qualifiers
source 1..1780
/db_xref="H-InvDB:HIT000036873"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5122 IMAGE:3449699"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1780
/gene="IRF6"
/gene_synonym="OFC6"
/gene_synonym="PIT"
/gene_synonym="PPS"
/gene_synonym="VWS"
/db_xref="GeneID:3664"
/db_xref="HGNC:HGNC:6121"
/db_xref="MIM:607199"
CDS 174..1577
/gene="IRF6"
/gene_synonym="OFC6"
/gene_synonym="PIT"
/gene_synonym="PPS"
/gene_synonym="VWS"
/codon_start=1
/product="interferon regulatory factor 6"
/protein_id="AAH14852.1"
/db_xref="GeneID:3664"
/db_xref="HGNC:HGNC:6121"
/db_xref="MIM:607199"
/translation="MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHAT
RHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKE
VPMNPVKIYQVCDIPQPQGSIINPGSTGSAPWDEKDNDVDEEDEEDELDQSQHHVPIQ
DTFPFLNINGSPMAPASVGNCSVGNCSPEAVWPKTEPLEMEVPQAPIQPFYSSPELWI
SSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKF
PGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAP
NLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILV
QVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQ
PMQPTPSMQLPPALPPQ"
BASE COUNT 470 a 453 c 445 g 412 t
ORIGIN
1 cttggctaag acgtcgagga gcgtggtagc gacgggtgat cttcgctgcg gacttggttc
61 ggagggacgt ccgcttctgg tggacagatt gagcaaagaa tctttgagcg gtcaagggaa
121 agacaagccg actcttcaga tccctgtgga cacactgcct gctcttccat atcatggccc
181 tccacccccg cagagtccgg ctaaagccct ggctggtggc ccaggtggat agtggcctct
241 accctgggct catctggcta cacagggact ctaaacgctt ccagattccc tggaaacatg
301 ccacccggca tagccctcaa caagaagagg aaaataccat ttttaaggcc tgggctgtag
361 agacagggaa gtaccaggaa ggggtggatg accctgaccc agctaaatgg aaggcccagc
421 tgcgctgtgc tctcaataag agcagagaat tcaacctgat gtatgatggc accaaggagg
481 tgcccatgaa cccagtgaag atatatcaag tgtgtgacat ccctcagccc cagggctcga
541 tcattaaccc aggatccaca gggtctgctc cctgggatga gaaggataat gatgtggatg
601 aagaagatga ggaagatgag ctggatcagt cgcagcacca tgttcccatc caggacacct
661 tccccttcct gaacatcaat ggttctccca tggcgccagc cagtgtgggc aattgcagtg
721 tgggcaactg cagcccggag gcagtgtggc ccaaaactga acccctggag atggaagtac
781 cccaggcacc tatacagccc ttctatagct ctccagaact gtggatcagc tctctcccaa
841 tgactgacct ggacatcaag tttcagtacc gtgggaagga gtacgggcag accatgaccg
901 tgagcaaccc tcagggctgc cgactcttct atggggacct gggtcccatg cctgaccagg
961 aggagctctt tggtcccgtc agcctggagc aggtcaaatt cccaggtcct gagcatatta
1021 ccaatgagaa gcagaagctg ttcactagca agctgctgga cgtcatggac agaggactga
1081 tcctggaggt cagcggtcat gccatttatg ccatcaggct gtgccagtgc aaggtgtact
1141 ggtctgggcc atgtgcccca tcacttgttg ctcccaacct gattgagaga caaaagaagg
1201 tcaagctatt ttgtctggaa acattcctta gcgatctcat tgcccaccag aaaggacaga
1261 tagagaagca gccaccgttt gagatctact tatgctttgg ggaagaatgg ccagatggga
1321 aaccattgga aaggaaactc atcttggttc aggtcattcc agtagtggct cggatgatct
1381 acgagatgtt ttctggtgat ttcacacgat cctttgatag tggcagtgtc cgcctgcaga
1441 tctcaacccc agacatcaag gataacatcg ttgctcagct gaagcagctg taccgcatcc
1501 ttcaaaccca ggagagctgg cagcccatgc agcccacccc cagcatgcaa ctgccccctg
1561 ccctgcctcc ccagtaattg tgaatgccat cttcttcctt ctctttttta taatattgta
1621 catatggatt tttttattgt ttagatttaa ccagctttta aatctctctt ttctctaaca
1681 gtgttagaag tttgtgattt tccaaatatg cctagattta aagctgattt aatttatgga
1741 aaaatcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
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