LOCUS BC014565 2091 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dual specificity phosphatase 4, mRNA (cDNA clone
MGC:2119 IMAGE:3050199), complete cds.
ACCESSION BC014565
VERSION BC014565.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2091)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2091)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC014565.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: h Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58331238.
FEATURES Location/Qualifiers
source 1..2091
/db_xref="H-InvDB:HIT000036781"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2119 IMAGE:3050199"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2091
/gene="DUSP4"
/gene_synonym="HVH2"
/gene_synonym="MKP-2"
/gene_synonym="MKP2"
/gene_synonym="TYP"
/db_xref="GeneID:1846"
/db_xref="HGNC:HGNC:3070"
/db_xref="MIM:602747"
CDS 391..1575
/gene="DUSP4"
/gene_synonym="HVH2"
/gene_synonym="MKP-2"
/gene_synonym="MKP2"
/gene_synonym="TYP"
/codon_start=1
/product="dual specificity phosphatase 4"
/protein_id="AAH14565.1"
/db_xref="GeneID:1846"
/db_xref="HGNC:HGNC:3070"
/db_xref="MIM:602747"
/translation="MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGK
CLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLY
SAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSK
TKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLD
ALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRV
LVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV
LATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSP
SC"
BASE COUNT 434 a 657 c 623 g 377 t
ORIGIN
1 gctgagcgcc ggaggagcgt aggcagggca gcgctggcgc cagcggcgac aggagccgcg
61 cgaccggcaa aaatacacgg gaggccgtcg ccgaaaagag tccgcggtcc tctctcgtaa
121 acacactctc ctccaccggc gcctccccct ccgctctgcg cgccgcccgg ctgggcgccc
181 gaggccgctc cgactgctat gtgaccgcga ggctgcggga ggaaggggac agggaagaag
241 aggctctccc gcgggagccc ttgaggacca agtttgcggc cacttctgca ggcgtccctt
301 cttagctctc gcctgcccct ttctgcagcc taggcggccc aggttctctt ctcttcctcg
361 cgcgcccagc cgcctcggtt cccggcgacc atggtgacga tggaggagct gcgggagatg
421 gactgcagtg tgctcaaaag gctgatgaac cgggacgaga atggcggcgg cgcgggcggc
481 agcggcagcc acggcaccct ggggctgccg agcggcggca agtgcctgct gctggactgc
541 agaccgttcc tggcgcacag cgcgggctac atcctaggtt cggtcaacgt gcgctgtaac
601 accatcgtgc ggcggcgggc taagggctcc gtgagcctgg agcagatcct gcccgccgag
661 gaggaggtac gcgcccgctt gcgctccggc ctctactcgg cggtcatcgt ctacgacgag
721 cgcagcccgc gcgccgagag cctccgcgag gacagcaccg tgtcgctggt ggtgcaggcg
781 ctgcgccgca acgccgagcg caccgacatc tgcctgctca aaggcggcta tgagaggttt
841 tcctccgagt acccagaatt ctgttctaaa accaaggccc tggcagccat cccacccccg
901 gttcccccca gcgccacaga gcccttggac ctgggctgca gctcctgtgg gaccccacta
961 cacgaccagg ggggtcctgt ggagatcctt cccttcctct acctcggcag tgcctaccat
1021 gctgcccgga gagacatgct ggacgccctg ggcatcacgg ctctgttgaa tgtctcctcg
1081 gactgcccaa accactttga aggacactat cagtacaagt gcatcccagt ggaagataac
1141 cacaaggccg acatcagctc ctggttcatg gaagccatag agtacatcga tgccgtgaag
1201 gactgccgtg ggcgcgtgct ggtgcactgc caggcgggca tctcgcggtc ggccaccatc
1261 tgcctggcct acctgatgat gaagaaacgg gtgaggctgg aggaggcctt cgagttcgtt
1321 aagcagcgcc gcagcatcat ctcgcccaac ttcagcttca tggggcagct gctgcagttc
1381 gagtcccagg tgctggccac gtcctgtgct gcggaggctg ctagcccctc gggacccctg
1441 cgggagcggg gcaagacccc cgccaccccc acctcgcagt tcgtcttcag ctttccggtc
1501 tccgtgggcg tgcactcggc ccccagcagc ctgccctacc tgcacagccc catcaccacc
1561 tctcccagct gttagagccg ccctgggggc cccagaacca gagctggctc ccagcaaggg
1621 taggacgggc cgcatgcggg cagaaagttg ggactgagca gctgggagca ggcgaccgag
1681 ctccttcccc atcatttctc cttggccaac gacgaggcca gccagaatgg caataaggac
1741 tccgaataca taataaaagc aaacagaaca ctccaactta gagcaataac ggctgccgca
1801 gcagccaggg aagaccttgg tttggtttat gtgtcagttt cacttttccg atagaaattt
1861 cttacctcat ttttttaagc agtaaggctt gaagtgatga aacccacaga tcctagcaaa
1921 tgtgcccaac cagctttact aaagggggag gaagggaggg caaagggatg agaagacaag
1981 tttcccaaaa gtgcctggtt ctgtgtactt gtccctttgt tgtcgttgtt gtagttaaag
2041 gaatttcatt ttttaaaaga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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