LOCUS BC014500 2579 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens leucine zipper-EF-hand containing transmembrane
protein 1, mRNA (cDNA clone MGC:23613 IMAGE:4860194), complete cds.
ACCESSION BC014500
VERSION BC014500.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2579)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2579)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: f Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2579
/db_xref="H-InvDB:HIT000036742"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23613 IMAGE:4860194"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2579
/gene="LETM1"
/db_xref="GeneID:3954"
/db_xref="HGNC:HGNC:6556"
/db_xref="MIM:604407"
CDS 198..2417
/gene="LETM1"
/codon_start=1
/product="leucine zipper-EF-hand containing transmembrane
protein 1"
/protein_id="AAH14500.1"
/db_xref="GeneID:3954"
/db_xref="HGNC:HGNC:6556"
/db_xref="MIM:604407"
/translation="MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGL
RNCLNVPFGCCTPIHPVYTSSRGDHLGCWALRPECLRIVSRAPWTSTSVGFVAVGPQC
LPVRGWHSSRPVRDDSVVEKSLKSLKDKNKKLEEGGPVYSPPAEVVVKKSLGQRVLDE
LKHYYHGFRLLWIDTKIAARMLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVV
PFMEFLLPVAVKLFPNMLPSTFETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNK
AAKGSATKDFSVFFQKIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLE
LQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTED
RLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQV
KVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPG
TEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEK
EELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLIS
QLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGK
VNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEEKVEEKEKAKEKAEKEVAEVKS"
BASE COUNT 614 a 713 c 815 g 437 t
ORIGIN
1 ctccggacgt ctgtgccggg acaaggccgc cgctggtgcc gggtccttga ggagagcgcc
61 tcccgtccga ggccagccgc ctctgtcagc cgtccgcgcg ggccgggtct gaagcgccgc
121 cgggacggcg aagagccgcg gccgccgcgg agaaggaggc agcgcaggag gccggagcgg
181 ccgccgcgcc cgagcacatg gcgtccatct tactgaggag ctgccgcggc cgggcgcccg
241 cccgcctccc gccgccgcct cggtacaccg tcccgcgggg tagtccaggg gatcctgctc
301 atctcagctg tgccagcacc ctggggttga ggaactgcct gaatgttcca tttggctgct
361 gcactcccat ccaccctgtg tacacatcct ccagaggcga tcacctcggc tgttgggctc
421 tgaggcccga gtgccttcgc atagtgtcga gagcgccatg gacctctacc tctgtgggtt
481 ttgtggctgt gggacctcag tgccttcctg tgcgtggctg gcactcttcg cgccctgttc
541 gcgatgactc ggtagtagag aagtccctca agtccttgaa ggacaagaac aagaagctgg
601 aggaaggcgg cccggtgtac agcccccccg cagaggtggt ggtgaagaag tccctggggc
661 agcgggtgct ggacgagctg aagcactact accatggctt ccgcctgcta tggatcgaca
721 ccaagatcgc ggcacgcatg ctctggcgca tcctcaacgg ccacagcctg acccgccggg
781 agcgcaggca gtttctccgg atctgcgctg acctcttccg cctggtgccg ttccttgtgt
841 tcgtggtggt gccgttcatg gagtttctgc tgcctgttgc tgtgaagctc ttccccaaca
901 tgttgccatc cacatttgag actcagtcac tcaaggagga gaggctgaag aaggagcttc
961 gggtcaagct ggagctggcc aagttcctcc aggacaccat cgaggagatg gccttgaaga
1021 acaaggcagc caagggcagc gccaccaaag acttctctgt gtttttccag aagatccggg
1081 aaacagggga gaggcccagc aatgaggaaa tcatgcgttt ttccaaatta tttgaggatg
1141 agctgaccct ggacaacctg acacggccgc agctggtggc cctgtgcaag ctgctggagc
1201 tacagtccat cggcaccaac aacttcctgc gcttccagct taccatgcgg ctgcgctcca
1261 taaaggcaga cgacaagctg attgctgagg aaggggtgga cagcctgaat gtcaaggagc
1321 tgcaggcagc gtgtcgggca cgaggcatgc gggccctggg cgtcacggaa gaccgcctga
1381 ggggtcagct gaagcagtgg ctggacctgc acctgcatca ggagatcccc acatcgctgc
1441 tcatcctgtc ccgggccatg tacctcccgg acaccctctc tccagccgac cagctcaagt
1501 ccacactgca gaccctccca gagattgtgg caaaggaagc acaggtgaaa gtggccgagg
1561 tggagggcga gcaggtggac aacaaggcca agctggaggc cacgctgcag gaggaggcgg
1621 ccatccagca ggagcaccgt gagaaggagc tgcagaagcg ctcggaggtg gcgaaggatt
1681 ttgagcccga acgtgtggta gctgctcccc aaaggccggg gaccgagcca cagccagaaa
1741 tgcctgacac agtcctgcag tcagagacct tgaaggacac tgccccggtg ctggagggct
1801 tgaaggagga agagatcacg aaggaggaaa tcgacatcct cagcgatgcc tgctctaagc
1861 tgcaggagca gaagaagtca ctcaccaagg agaaggagga gctggagctg ctgaaggagg
1921 atgtgcagga ctacagcgag gacttgcagg agatcaagaa ggaactttca aagactggtg
1981 aagaaaaata cgtggaagaa tctaaagcca gcaagagatt gacaaaaagg gtgcagcaaa
2041 tgatcgggca gatcgatggc ttgatctcgc agctggagat ggaccagcag gctggcaagc
2101 tggccccggc caacggcatg cccacggggg agaacgtcat cagtgtcgct gagctcatca
2161 acgccatgaa gcaagtcaag cacattcccg aaagcaagct caccagcctg gccgcagcac
2221 tggatgaaaa caaggatggc aaggtcaaca tcgacgacct cgtcaaggtg attgagctgg
2281 tggacaaaga agatgttcac atctccacca gccaggtggc tgagattgta gcaacactgg
2341 aaaaagagga gaaggtggag gagaaggaga aggccaaaga gaaggcagag aaggaggtcg
2401 cagaggtgaa gagctagaac cactggcctg ggcacctgtc ctcctgctgt gccgtcaccc
2461 tggcaagggc cgtgagggcg attgctttgt ggtgattctc agtggctcat ctaatatttt
2521 ggctggaata aatcagagac ttccataaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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