LOCUS BC014488 1433 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase,
4, mRNA (cDNA clone MGC:23214 IMAGE:4899042), complete cds.
ACCESSION BC014488
VERSION BC014488.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1433)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1433)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24430154.
FEATURES Location/Qualifiers
source 1..1433
/db_xref="H-InvDB:HIT000036735"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23214 IMAGE:4899042"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_42"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1433
/gene="PSMC4"
/gene_synonym="MGC13687"
/gene_synonym="MGC23214"
/gene_synonym="MGC8570"
/gene_synonym="S6"
/gene_synonym="TBP7"
/db_xref="GeneID:5704"
/db_xref="HGNC:HGNC:9551"
/db_xref="MIM:602707"
CDS 21..1277
/gene="PSMC4"
/gene_synonym="MGC13687"
/gene_synonym="MGC23214"
/gene_synonym="MGC8570"
/gene_synonym="S6"
/gene_synonym="TBP7"
/codon_start=1
/product="proteasome (prosome, macropain) 26S subunit,
ATPase, 4"
/protein_id="AAH14488.1"
/db_xref="GeneID:5704"
/db_xref="HGNC:HGNC:9551"
/db_xref="MIM:602707"
/translation="MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRY
KKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAI
VGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKP
DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKA
VAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFD
AQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP
LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRY
IVLAKDFEKAYKTVIKKDEQEHEFYK"
BASE COUNT 374 a 388 c 386 g 285 t
ORIGIN
1 cagaggccgg cttggtcact atggaggaga taggcatctt ggtggagaag gctcaggatg
61 agatcccagc actgtccgtg tcccggcccc agaccggcct gtccttcctg ggccctgagc
121 ctgaggacct ggaggacctg tacagccgct acaagaagct gcagcaagag ctggagttcc
181 tggaggtgca ggaggaatac atcaaagatg agcaaaagaa cctgaaaaag gaatttctcc
241 atgcccagga ggaggtgaag cgaatccaaa gcatcccgct ggtcatcgga caatttctgg
301 aggctgtgga tcagaataca gccatcgtgg gctctaccac aggctccaac tattatgtgc
361 gcatcctgag caccatcgat cgggagctgc tcaagcccaa cgcctcagtg gccctccaca
421 agcacagcaa tgcactggtg gacgtgctgc cccccgaagc cgacagcagc atcatgatgc
481 tcacctcaga ccagaagcca gatgtgatgt acgcggacat cggaggcatg gacatccaga
541 agcaggaggt gcgggaggcc gtggagctcc cgctcacgca tttcgagctc tacaagcaga
601 tcggcatcga tcccccccga ggcgtcctca tgtatggccc acctggctgt gggaagacca
661 tgttggcaaa ggcggtggca catcacacaa cagctgcatt catccgggtc gtgggctcgg
721 agtttgtaca gaagtatctg ggtgagggcc cccgcatggt ccgggatgtg ttccgcctgg
781 ccaaggagaa tgcacctgcc atcatcttca tagacgagat tgatgccatc gccaccaaga
841 gattcgatgc tcagacaggg gccgacaggg aggttcagag gatcctgctg gagctgctga
901 atcagatgga tggatttgat cagaatgtca atgtcaaggt aatcatggcc acaaacagag
961 cagacaccct ggatccggcc ctgctacggc caggacggct ggaccgtaaa attgaatttc
1021 cacttcctga ccgccgccag aagagattga ttttctccac tatcactagc aagatgaacc
1081 tctctgagga ggttgacttg gaagactatg tggcccggcc agataagatt tcaggagctg
1141 atattaactc catctgtcag gagagtggaa tgttggctgt ccgtgaaaac cgctacattg
1201 tcctggccaa ggacttcgag aaagcataca agactgtcat caagaaggac gagcaggagc
1261 atgagtttta caagtgaccc ttcccttccc tccaccacac cactcagggg ctggggcttc
1321 tctcgcaccc ccagcacctc tgtcccaaaa cctcattccc ttttttcttt acccaggatt
1381 ggtttcttca ataaatagat aagatcgaat ccaaaaaaaa aaaaaaaaaa aaa
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