LOCUS BC014472 1603 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens endothelin receptor type B, mRNA (cDNA clone MGC:23118
IMAGE:4868863), complete cds.
ACCESSION BC014472
VERSION BC014472.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1603)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1603)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: l Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503466.
FEATURES Location/Qualifiers
source 1..1603
/db_xref="H-InvDB:HIT000036721"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23118 IMAGE:4868863"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1603
/gene="EDNRB"
/gene_synonym="ABCDS"
/gene_synonym="ETB"
/gene_synonym="ETRB"
/gene_synonym="HSCR"
/gene_synonym="HSCR2"
/db_xref="GeneID:1910"
/db_xref="MIM:131244"
CDS 236..1564
/gene="EDNRB"
/gene_synonym="ABCDS"
/gene_synonym="ETB"
/gene_synonym="ETRB"
/gene_synonym="HSCR"
/gene_synonym="HSCR2"
/codon_start=1
/product="EDNRB protein"
/protein_id="AAH14472.1"
/db_xref="GeneID:1910"
/db_xref="MIM:131244"
/translation="MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAE
IMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKY
INTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVY
KLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWT
AVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWW
LFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFAL
CWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKR
FKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS"
misc_feature 587..1387
/gene="EDNRB"
/gene_synonym="ABCDS"
/gene_synonym="ETB"
/gene_synonym="ETRB"
/gene_synonym="HSCR"
/gene_synonym="HSCR2"
/note="7tm_1; Region: 7 transmembrane receptor (rhodopsin
family)"
/db_xref="CDD:pfam00001"
BASE COUNT 407 a 379 c 399 g 418 t
ORIGIN
1 caggaaggag tttcgacccg cgctggcgag tcatgagcgc caagtttccc actggcgcgc
61 aaacttgagt tacttttgag cgtggatact ggcgaagagg ctgcgggcgg tattagcgtt
121 tgcagcgact tggctcgggc agctgaccca agtgtcctgt cttccttcct ctgcttgtct
181 ctaggctctg aaactgcgga gcggccaccg gacgccttct ggagcaggta gcagcatgca
241 gccgcctcca agtctgtgcg gacgcgccct ggttgcgctg gttcttgcct gcggcctgtc
301 gcggatctgg ggagaggaga gaggcttccc gcctgacagg gccactccgc ttttgcaaac
361 cgcagagata atgacgccac ccactaagac cttatggccc aagggttcca acgccagtct
421 ggcgcggtcg ttggcacctg cggaggtgcc taaaggagac aggacggcag gatctccgcc
481 acgcaccatc tcccctcccc cgtgccaagg acccatcgag atcaaggaga ctttcaaata
541 catcaacacg gttgtgtcct gccttgtgtt cgtgctgggg atcatcggga actccacact
601 tctgagaatt atctacaaga acaagtgcat gcgaaacggt cccaatatct tgatcgccag
661 cttggctctg ggagacctgc tgcacatcgt cattgacatc cctatcaatg tctacaagct
721 gctggcagag gactggccat ttggagctga gatgtgtaag ctggtgcctt tcatacagaa
781 agcctccgtg ggaatcactg tgctgagtct atgtgctctg agtattgaca gatatcgagc
841 tgttgcttct tggagtagaa ttaaaggaat tggggttcca aaatggacag cagtagaaat
901 tgttttgatt tgggtggtct ctgtggttct ggctgtccct gaagccatag gttttgatat
961 aattacgatg gactacaaag gaagttatct gcgaatctgc ttgcttcatc ccgttcagaa
1021 gacagctttc atgcagtttt acaagacagc aaaagattgg tggctgttca gtttctattt
1081 ctgcttgcca ttggccatca ctgcattttt ttatacacta atgacctgtg aaatgttgag
1141 aaagaaaagt ggcatgcaga ttgctttaaa tgatcaccta aagcagagac gggaagtggc
1201 caaaaccgtc ttttgcctgg tccttgtctt tgccctctgc tggcttcccc ttcacctcag
1261 caggattctg aagctcactc tttataatca gaatgatccc aatagatgtg aacttttgag
1321 ctttctgttg gtattggact atattggtat caacatggct tcactgaatt cctgcattaa
1381 cccaattgct ctgtatttgg tgagcaaaag attcaaaaac tgctttaagt catgcttatg
1441 ctgctggtgc cagtcatttg aagaaaaaca gtccttggag gaaaagcagt cgtgcttaaa
1501 gttcaaagct aatgatcacg gatatgacaa cttccgttcc agtaataaat acagctcatc
1561 ttgaaagaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//