LOCUS BC014456 2090 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cholinergic receptor, nicotinic, alpha 6, mRNA (cDNA
clone MGC:23050 IMAGE:4862198), complete cds.
ACCESSION BC014456
VERSION BC014456.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2090)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2090)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: h Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361147.
FEATURES Location/Qualifiers
source 1..2090
/db_xref="H-InvDB:HIT000036712"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23050 IMAGE:4862198"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2090
/gene="CHRNA6"
/gene_synonym="CHNRA6"
/db_xref="GeneID:8973"
/db_xref="HGNC:HGNC:15963"
/db_xref="MIM:606888"
CDS 47..1531
/gene="CHRNA6"
/gene_synonym="CHNRA6"
/codon_start=1
/product="cholinergic receptor, nicotinic, alpha 6"
/protein_id="AAH14456.1"
/db_xref="GeneID:8973"
/db_xref="HGNC:HGNC:15963"
/db_xref="MIM:606888"
/translation="MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSH
YNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEY
DGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPM
DITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDI
KYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCI
SVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTT
HTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHL
KECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETK
EVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS"
BASE COUNT 585 a 450 c 460 g 595 t
ORIGIN
1 ccacaatcct ttgcctagga aaaaggaatc caagtgtgtt ttaaccatgc tgaccagcaa
61 ggggcaggga ttccttcatg ggggcttgtg tctctggctg tgtgtgttca cacctttctt
121 taaaggctgt gtgggctgtg caactgagga gaggctcttc cacaaactgt tttctcatta
181 caaccagttc atcaggcctg tggaaaacgt ttccgaccct gtcacggtac actttgaagt
241 ggccatcacc cagctggcca acgtggatga agtaaaccag atcatggaaa ccaatttgtg
301 gctgcgtcac atctggaatg attataaatt gcgctgggat ccaatggaat atgatggcat
361 tgagactctt cgcgttcctg cagataagat ttggaagccc gacattgttc tctataacaa
421 tgctgttggt gacttccaag tagaaggcaa aacaaaagct cttcttaaat acaatggcat
481 gataacctgg actccaccag ctatttttaa gagttcctgc cctatggata tcaccttttt
541 cccttttgat catcaaaact gttccctaaa atttggttcc tggacgtatg acaaagctga
601 aattgatctt ctaatcattg gatcaaaagt ggatatgaat gatttttggg aaaacagtga
661 atgggaaatc attgatgcct ctggctacaa acatgacatc aaatacaact gttgtgaaga
721 gatatacaca gatataacct attctttcta cattagaaga ttgccgatgt tttacacgat
781 taatctgatc atcccttgtc tctttatttc atttctaacc gtgttggtct tttaccttcc
841 ttcggactgt ggtgaaaaag tgacgctttg tatttcagtc ctgctttctc tgactgtgtt
901 tttgctggtc atcacagaaa ccatcccatc cacatctctg gtggtcccac tggtgggtga
961 gtacctgctg ttcaccatga tctttgtcac actgtccatc gtggtgactg tgtttgtgtt
1021 gaacatacac taccgcaccc caaccacgca cacaatgccc aggtgggtga agacagtttt
1081 cctgaagctg ctgccccagg tcctgctgat gaggtggcct ctggacaaga caaggggcac
1141 aggctctgat gcagtgccca gaggccttgc caggaggcct gccaaaggca agcttgcaag
1201 ccatggggaa cccagacatc ttaaagaatg cttccattgt cacaaatcaa atgagcttgc
1261 cacaagcaag agaagattaa gtcatcagcc attacagtgg gtggtggaaa attcggagca
1321 ctcgcctgaa gttgaagatg tgattaacag tgttcagttc atagcagaaa acatgaagag
1381 ccacaatgaa accaaggagg tagaagatga ctggaaatac gtggccatgg tggtggacag
1441 agtatttctt tgggtattta taattgtctg tgtatttgga actgcagggc tatttctaca
1501 gccactactt gggaacacag gaaaatctta aaatgtattt tcttttatgt tcagaaattt
1561 acagacacca tatttgttct gcattccctg ccacaaggaa aggaaagcaa aggcttccca
1621 cccaagtccc ccatctgcta aaactgatgg ctacatggaa aaagaggact ttcttgcaca
1681 ttaggaagca gaatatcctc cagtgtagca cagggggaga agtgagaagt gttatgacat
1741 tagtgccctg attgggcagc acccacggct acagtatcag gtcaggtttc tcgtgtctgt
1801 gtgtttggct tctaaagaca agaatgactt acaatacagc ctaattatgt aattaacatc
1861 aagccacact aaaaagttct gctgtacctc cagtggatgc tgtttctcag tattatgaca
1921 tgtgacaggt gaactctggg aattggacca tgcaacattt gtgaactgtt tgcaacactt
1981 tgtgaactat tgcatccttg atttcttgtg catgtctctg taatgtaact caccctcctc
2041 agcattattt gatacactga ttgttagttt taaaaaaaaa aaaaaaaaaa
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