LOCUS BC014414 1619 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens F-box and leucine-rich repeat protein 8, mRNA (cDNA
clone MGC:19959 IMAGE:4548146), complete cds.
ACCESSION BC014414
VERSION BC014414.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1619)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1619)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: a Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22547145.
FEATURES Location/Qualifiers
source 1..1619
/db_xref="H-InvDB:HIT000036683"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19959 IMAGE:4548146"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1619
/gene="FBXL8"
/gene_synonym="FBL8"
/gene_synonym="FLJ11278"
/gene_synonym="MGC19959"
/db_xref="GeneID:55336"
/db_xref="HGNC:HGNC:17875"
/db_xref="MIM:609077"
CDS 121..1245
/gene="FBXL8"
/gene_synonym="FBL8"
/gene_synonym="FLJ11278"
/gene_synonym="MGC19959"
/codon_start=1
/product="F-box and leucine-rich repeat protein 8"
/protein_id="AAH14414.1"
/db_xref="GeneID:55336"
/db_xref="HGNC:HGNC:17875"
/db_xref="MIM:609077"
/translation="MAEPGEGLPEEVLALIFRHLSLRDRAAAARVCRAWAAAATCSAV
WHDTKISCECELEGMLPPYLSACLDHIHNLRLEFEPSRKPSRRAAIELLMVLAGRAPG
LRGLRLECRGEKPLFDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARS
CPELHSLFLDNSTLVGSVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAP
FALLALRCACPEDARASPLPNEAWVALRRRHPGLAVELELEPALPAESVTRVLQPAVP
VAALRLNLSGDTVGPVRFAAHHYAATLCALEVRAAASAELNAALEELAARCAALREVH
CFCVVSHSVLDAFRAHCPRLRTYTLKLTREPHPWRPTLVA"
BASE COUNT 242 a 577 c 525 g 275 t
ORIGIN
1 gcttcccgtc cgctgtcctc tgctgccagt cccctgcccc gggcaaagcc catctggtcc
61 gccgagcagg ccggagctat tgggagtggc ggatcctccc accccagccg gatctgggcc
121 atggccgagc ctggagaggg actgccagag gaggtgctgg cactcatctt ccgccacctg
181 tccctgagag accgtgctgc cgccgccagg gtctgcaggg cctgggccgc cgctgctacc
241 tgcagcgccg tgtggcacga cacaaaaatc agttgcgaat gtgagctgga aggcatgctg
301 ccaccttatc tgtccgcctg cctcgaccac attcacaacc tacggctgga atttgagcca
361 tcgaggaagc cgagccgccg ggcggccatc gagctgctga tggttctggc gggccgtgcc
421 ccggggctgc gaggcctgcg cctggagtgc cgcggagaaa aaccgctctt cgacgcgggc
481 cgcgacgtcc tggaggctgt gcacgctgta tgcggggcgg ccagccagct acgccacctc
541 gacctgcggc gcttgtcctt cacactggac gacgcgctgg tgctgcaggc ggcgcgcagc
601 tgtcccgagc tccacagcct ttttctggac aacagtaccc tagtgggcag cgtgggtccc
661 ggctcagtgc tcgagctact ggaggcctgc ccgcgcctgc gcgctctcgg cctgcaccta
721 gccagtttgt cgcacgccat cctcgaagca ctggcggcgc cagaccgagc gcctttcgcg
781 ctcttggctc tgcggtgcgc gtgccccgaa gatgcacgcg cgtccccgct gcccaacgaa
841 gcctgggtcg cgttgcgccg ccgccaccct gggctggcag tggagctgga gctggagccc
901 gcgctgcccg ctgagagcgt gacgcgcgtc ctgcagccag ccgtccccgt ggctgcgctg
961 cgcctcaacc tctcaggcga caccgtaggc ccagtgcgct tcgcagcaca ccactacgcc
1021 gcaaccctgt gcgcgctcga ggtgcgcgca gccgcttcgg ccgagctgaa cgccgcgctg
1081 gaggagctgg cggcgcgctg cgcggccctg cgcgaggtgc attgtttctg cgtggtgagc
1141 cactcggtgc tggacgcctt ccgcgcgcac tgcccgcgcc tgcgcaccta taccctcaag
1201 ctcacgcgcg agccgcatcc ctggaggcct acgctcgtgg cgtgattggg cgacttctct
1261 cccccgtccc cgtggacgta agcgctctga gagggaacgg gggggggtgt ccaggcgcgc
1321 cccgagtgct agtgccttct tttgggattg ttgccccccg ggtctttacc gagttgggaa
1381 ctgtgatggc atcgggacca gtcctgggcg ccctgagacc actcgctgct ctcaccctct
1441 gcagacgccc cacccgctcg gtcctggaca cactgccccc ctctcttgcc tccacccctc
1501 tgcggactct gcagctccgc ggccccggcg cagggagagg gagggcacgg gcgcgggccg
1561 ggcctcaagg gtgagtgtga aataaacaaa tcctgcagtg aaaaaaaaaa aaaaaaaaa
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