LOCUS BC014168 1872 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens aldehyde dehydrogenase 3 family, member B1, mRNA (cDNA
clone IMAGE:4551195), partial cds.
ACCESSION BC014168
VERSION BC014168.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1872)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1872)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC014168.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: g Column: 20.
FEATURES Location/Qualifiers
source 1..1872
/db_xref="H-InvDB:HIT000088302"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4551195"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1872
/gene="ALDH3B1"
/gene_synonym="ALDH4"
/gene_synonym="ALDH7"
/db_xref="GeneID:221"
/db_xref="MIM:600466"
CDS <1..480
/gene="ALDH3B1"
/gene_synonym="ALDH4"
/gene_synonym="ALDH7"
/codon_start=1
/product="ALDH3B1 protein"
/protein_id="AAH14168.2"
/db_xref="GeneID:221"
/db_xref="MIM:600466"
/translation="DESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIE
FINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMG
RYHGKFSFDTFSHHRACLLRSPGMEKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL"
misc_feature 1..369
/gene="ALDH3B1"
/gene_synonym="ALDH4"
/gene_synonym="ALDH7"
/note="aldedh; Region: Aldehyde dehydrogenase family. This
family of dehydrogenases act on aldehyde substrates.
Members use NADP as a cofactor. The family includes the
following members: The prototypical members are the
aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde
dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase
EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28.
Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27.
Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9.
Delta-1-pyrroline-5-carboxylate dehydrogenase EC:
1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10.
Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This
family also includes omega crystallin, an eye lens protein
from squid and octopus that has little aldehyde
dehydrogenase activity"
/db_xref="CDD:pfam00171"
BASE COUNT 430 a 561 c 505 g 376 t
ORIGIN
1 gatgagagcg atcgctacat cgcccccacg gtgctggtgg atgtgcagga gatggagcct
61 gtgatgcagg aggagatctt cgggcccatc ctgcccatcg tgaacgtgca gagcttggac
121 gaggccatcg agttcatcaa ccggcgggag aagcccctgg ccctgtacgc cttctccaac
181 agcagccagg tggtcaagcg ggtgctgacc cagaccagca gcgggggctt ctgtgggaac
241 gacggcttca tgcacatgac cctggccagc ctgccttttg gaggagtggg tgccagtggg
301 atgggccggt accatggcaa gttctccttc gacaccttct cccaccatcg cgcctgcctc
361 ctgcgcagcc cggggatgga gaagctcaac gccctccgct acccgccgca atcgccgcgc
421 cgcctgagga tgctgctggt ggccatggag gcccaaggct gcagctgcac actgctctga
481 gcccttcccc aggcccaggc tgtagaccac catgacagct gtcgcctgcg gctggtggag
541 acggggcctg ggctcccggg cccgaggagg aaaaggattg ccaaggctcc agggcacccc
601 tcaaagcagc gcctgcctcc tccctcctgg gtcttccctc tccctgcctc agcctcctcc
661 ctcagccgct cccaaccatg agagccgagg tgggaggcat gggaaacagt gcagtgactc
721 accccctgcc cccgcaccaa ccacccatat tcaggagaag aggacagaca cggcacctct
781 gagtcacccc tctcctgtgg agcgggcgtc cgaggggccc tggcatctga ctcaggccac
841 accatggaat cactgcatcc aaggccattc ctgccctctc tgagtctcag tttttccatt
901 tgttcagtgg agagaattaa ccattgatac ctcctggctg ggtgaggcgg ctcacacctg
961 taatcccagc actttgggag gccgaggcag gcggatcacc tgaaatcagg agttcaagat
1021 cagcctggct aacatggcga aaccccgtct ctactaaaaa tacaaaaatt agcctggcgt
1081 ggtggcgcat gcctgtaatc ccagctactc aggaggctaa ggcaggagaa tcgcttgaac
1141 ccgggaggtg gaggttgccg tgagctgaga ttgcgtcact gaactccggc ctgggtgaca
1201 gaaggaggct ctgccttaaa aaaaaaaaaa aaaaaaaaaa acctcctggg actgttgcaa
1261 ggatgaaatg aaggattgag ggattgaggg attgctgagc tggagctcca ggtgtcctat
1321 ctttctcagt ggggtggcac ggagcggggc cgcctccctc ttctctccag gcaggtgggg
1381 ctgtggttat gcgatagggt ctcccttccc tccagcccat gccagaggag cttgtaactc
1441 tttatcctca tggtgcccac tacgagtcat actcttcccc atgctgctca tcctcctggg
1501 ccccatccac tcagccaaag cagaatgcag ggtttcctgc ctgacaaccc ttctcacctc
1561 ccaagtccca cttttgaaca agctgatgat tctgaaactg gcccaatttc ctaacaagcc
1621 ggatgcttga gaaacctaca tttggacaat gagaggctgc tcctgcggcc tgcgggccac
1681 ctcctcttcc ttggctcctg ctttcttttt agactatatc aacctacaac tttagtcggg
1741 aagagggaca ggggtggacc tgagtttcgt ctcctgtctc tctggctgat gtcacctgaa
1801 taaagccttc ttccctggca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaaaaaaa aa
//