LOCUS BC014137 2358 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens opioid growth factor receptor, mRNA (cDNA clone
MGC:20786 IMAGE:4643904), complete cds.
ACCESSION BC014137
VERSION BC014137.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2358)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2358)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC014137.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: o Column: 1.
FEATURES Location/Qualifiers
source 1..2358
/db_xref="H-InvDB:HIT000036539"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20786 IMAGE:4643904"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2358
/gene="OGFR"
/db_xref="GeneID:11054"
/db_xref="MIM:606459"
CDS 11..1984
/gene="OGFR"
/codon_start=1
/product="OGFR protein"
/protein_id="AAH14137.1"
/db_xref="GeneID:11054"
/db_xref="MIM:606459"
/translation="MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEE
SEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIR
FLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSS
QEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILK
SLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWE
HFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEH
SKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRR
EQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR
VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRT
GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP
AGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP
SPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP"
misc_feature 251..895
/gene="OGFR"
/note="OGFr_N; Region: Opioid growth factor receptor
(OGFr) conserved region. Opioid peptides act as growth
factors in neural and non-neural cells and tissues, in
addition to serving in neurotransmission/neuromodulation
in the nervous system. The Opioid growth factor receptor
is an integral membrane protein associated with the
nucleus. The conserved region is situated at the
N-terminus of the member proteins with a series of
imperfect repeats lying immediately to its C-terminus"
/db_xref="CDD:pfam04664"
misc_feature 1697..1921
/gene="OGFR"
/note="Trypano_PARP; Region: Procyclic acidic repetitive
protein (PARP). This family consists of several
Trypanosoma brucei procyclic acidic repetitive protein
(PARP) like sequences. The procyclic acidic repetitive
protein (parp) genes of Trypanosoma brucei encode a small
family of abundant surface proteins whose expression is
restricted to the procyclic form of the parasite. They are
found at two unlinked loci, parpA and parpB"
/db_xref="CDD:pfam05887"
BASE COUNT 502 a 723 c 820 g 313 t
ORIGIN
1 gccgccgagc atggacgacc ccgactgcga ctccacctgg gaggaggacg aggaggatgc
61 ggaggacgcg gaggacgagg actgcgagga cggcgaggcc gccggcgcga gggacgcgga
121 cgcaggggac gaggacgagg agtcggagga gccgcgggcg gcgcggccca gctcgttcca
181 gtccagaatg acagggtcca gaaactggcg agccacgagg gacatgtgta ggtatcggca
241 caactatccg gatctggtgg aacgagactg caatggggac acgccaaacc tgagtttcta
301 cagaaatgag atccgcttcc tgcccaacgg ctgtttcatt gaggacattc ttcagaactg
361 gacggacaac tatgacctcc ttgaggacaa tcactcctac atccagtggc tgtttcctct
421 gcgagaacca ggagtgaact ggcatgccaa gcccctcacg ctcagggagg tcgaggtgtt
481 taaaagctcc caggagatcc aggagcggct tgtccgggcc tacgagctca tgctgggctt
541 ctacgggatc cggctggagg accgaggcac gggcacggtg ggccgagcac agaactacca
601 gaagcgcttc cagaacctga actggcgcag ccacaacaac ctccgcatca cacgcatcct
661 caagtcgctg ggtgagctgg gcctcgagca cttccaggcg ccgctggtcc gcttcttcct
721 ggaggagacg ctggtgcggc gggagctgcc gggggtgcgg cagagtgccc tggactactt
781 catgttcgcc gtgcgctgcc gacaccagcg ccgccagctg gtgcacttcg cctgggagca
841 cttccggccc cgctgcaagt tcgtctgggg gccccaagac aagctgcgga ggttcaagcc
901 cagctctctg ccccatccgc tcgagggctc caggaaggtg gaggaggaag gaagccccgg
961 ggaccccgac cacgaggcca gcacccaggg tcggacctgt gggccagagc atagcaaggg
1021 tgggggcagg gtggacgagg ggccccagcc acggagcgtg gagccccagg atgcgggacc
1081 cctggagagg agccaggggg atgaggcagg gggccacggg gaagataggc cggagccctt
1141 aagccccaaa gagagcaaga agaggaagct ggagctgagc cggcgggagc agccgcccac
1201 agagccaggc cctcagagtg cctcagaggt ggagaagatc gctctgaatt tggaggggtg
1261 tgccctcagc cagggcagcc tcaggacggg gacccaggaa gtgggcggtc aggaccctgg
1321 ggaggcagtg cagccctgcc gccaacccct gggagccagg gtggccgaca aggtgaggaa
1381 gcggaggaag gtggatgagg gtgctgggga cagtgctgcg gtggccagtg gtggtgccca
1441 gaccttggcc cttgccgggt cccctgcccc atcggggcac cccaaggctg gacacagtga
1501 gaacggggtt gaggaggaca cagaaggtcg aacggggccc aaagaaggta cccctgggag
1561 cccatcggag accccaggcc ccagcccagc aggacctgca ggggacgagc cagccgagag
1621 cccatcggag accccaggcc cccgcccagc aggacctgca ggggacgagc cagccgagag
1681 cccatcggag accccaggcc ccagcccggc aggacctaca agggatgagc cagccgagag
1741 cccatcggag accccaggcc cccgcccagc aggacctgca ggggacgagc cagccgagag
1801 cccatcggag accccaggcc cccgcccggc aggacctgca ggggacgagc cagccgagag
1861 cccatcggag accccaggcc ccagcccggc aggacctaca agggatgagc cagccaaggc
1921 gggggaggca gcagagttgc aggacgcaga ggtggagtct tctgccaagt ctgggaagcc
1981 ttaaggaaag gagtgcccgt cggcgtcttg gtcctcctgt ccctgctgca ggggctgggg
2041 cctccggagc tgctgcgggc tcccctcagg ctctgcttcg tgacccgtga cccatgaccc
2101 acagtgctgg cctcctgtgg ggccactata gcagccacca gaagccgcga ggccctcagg
2161 gaagcccaag gcctgcagaa gcctcctggc ctggctgtgt cttccccacc cagctctccc
2221 ctgcgcccct gtctttgtaa attgaccctt ctggagtggg gggcggcggg cagggctgct
2281 tttcttagtc tgataccaag caaggccttt tctgaataaa ttcatttgac tttgaaaaaa
2341 aaaaaaaaaa aaaaaaaa
//