LOCUS BC014130 2316 bp mRNA linear HUM 16-FEB-2007
DEFINITION Homo sapiens F-box and WD repeat domain containing 5, mRNA (cDNA
clone MGC:20962 IMAGE:4620371), complete cds.
ACCESSION BC014130
VERSION BC014130.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2316)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2316)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: m Column: 1.
FEATURES Location/Qualifiers
source 1..2316
/db_xref="H-InvDB:HIT000036535"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20962 IMAGE:4620371"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2316
/gene="FBXW5"
/gene_synonym="DKFZP434B205"
/gene_synonym="Fbw5"
/gene_synonym="RP11-229P13.10"
/db_xref="GeneID:54461"
/db_xref="HGNC:HGNC:13613"
/db_xref="MIM:609072"
CDS 81..1781
/gene="FBXW5"
/gene_synonym="DKFZP434B205"
/gene_synonym="Fbw5"
/gene_synonym="RP11-229P13.10"
/codon_start=1
/product="F-box and WD repeat domain containing 5"
/protein_id="AAH14130.1"
/db_xref="GeneID:54461"
/db_xref="HGNC:HGNC:13613"
/db_xref="MIM:609072"
/translation="MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEF
LWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSH
SGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFL
GPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVL
WLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSP
CRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQG
HTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFF
DALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDL
KTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLR
HEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
"
BASE COUNT 441 a 763 c 730 g 382 t
ORIGIN
1 ggaagcgggt ccgggtcgcg cagggcgggg gcggcgcagc gggcggaggc ggccgtgggc
61 cgcctgggca gaatgtcacg atggacgagg gcggcacgcc cctgctcccc gacagcctgg
121 tctaccagat cttcctgagc ctgggcccgg ccgacgtgct ggccgccggg ctggtgtgcc
181 gccaatggca ggccgtgtcg cgggacgagt tcctgtggag ggagcagttc taccgctact
241 accaggtggc ccgcgacgtg ccccgacacc cagcggccat gtcctggtac gaggagttcc
301 agcggctgta tgacacggtg ccctgcgtgg aggtgcagac gctgcgggaa cacacagacc
361 aggtcctgca cctcagcttc tcccattccg ggtaccagtt cgcgtcctgc tccaaggact
421 gcactgtgaa gatctggagc aacgacctga ccatctcgct gctgcacagc gcggacatgc
481 ggccctacaa ctggagctac acccagttct cccagttcaa caaggacgac tcgctactgc
541 tggcctcggg ggtgttcctg gggccgcaca actcctcatc cggcgagatt gctgtcatca
601 gcctagactc cttcgcgctg ctgtcccgcg tgcggaacaa gccctatgac gtgtttggct
661 gttggctcac cgagaccagc ctcatctcgg ggaacctgca ccgcatcgga gatatcacct
721 cctgctcggt gctgtggctc aacaatgcct tccaggatgt ggagtcagag aacgtcaacg
781 tggtgaagcg gctgttcaag atccagaacc tcaatgccag caccgtccgc acggtgatgg
841 tggccgactg cagccgcttc gacagccctg acctgctgct ggaagccggt gacccggcca
901 cgtccccctg ccgcatcttt gacctgggca gcgacaacga ggaggtggtg gctggcccgg
961 cccccgccca cgccaaggag ggcttgcggc actttctgga ccgcgtgctg gaggggcggg
1021 cgcagccaca gctgtcggag cgcatgctag agaccaaggt ggccgagctg ctggcccagg
1081 gccacaccaa gccacccgag cgcagtgcca caggcgccaa gagcaagtac ctcatcttca
1141 ccactggctg cctcacctac tccccacacc agatcggcat caagcagatc ctgccacacc
1201 agatgaccac ggcagggccc gtgctgggtg agggccgggg ctccgatgcc ttcttcgacg
1261 cgctggacca cgtcatagac atacacggac acatcatcgg catgggcctg tcgcccgaca
1321 acaggtacct gtacgtgaac agccgcgcct ggcccaacgg tgcggtggtg gccgacccca
1381 tgcagccgcc accaatcgcg gaggagattg acctgctggt gttcgacctc aagaccatgc
1441 gggaggtgag gcgggctctg cgtgcgcacc gcgcctacac gcccaacgac gagtgcttct
1501 tcatcttcct ggacgtcagc agggacttcg tggccagcgg ggcggaggac cggcacggct
1561 acatctggga ccgccactac aacatctgtc tggccaggct gcggcacgag gatgtggtca
1621 actcagtggt cttcagtccc caggagcagg agctgctgct cacggccagc gacgacgcca
1681 ccatcaaagc ctggcgctcc ccacgcacca tgcgcgtcct ccaggcacct cgcccacggc
1741 ctcgcacctt cttctcctgg cttgccagcc agaggcgctg aggtgtgctg ggtgcactgg
1801 agccaccggg accccttgag gacatcgcca ggctctgtgg ctttttcccg agcgggagag
1861 gtggagatgc ttatagcagt tacgccttag gaaggggaca accaggcccc gccacacgct
1921 cacacacaaa cctgctcacg cagctgtgat gcttggcacg gggtggccag tgcagatgga
1981 gcccaaggcc ccctcggcct cctgggcaac ttggggtaca caggatactg ggggtgccgc
2041 tcctcactca accccaggct aggggtacac ctgacccagc tggcctcggc ccggggcacc
2101 ttcggctggt cctgtggggc cctggacggt ggcccagtgg tggcaggggc tgctcctggc
2161 tgtggttgtg cgcccggggc ttgggagcgg ccggtcacgc tgctgtgggc ccgagtgtgt
2221 tgcatgtcca cgcaccaccc gttcagggcc ctgaataaac agttggcaac agcaaaaaaa
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//