LOCUS BC014079 1594 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens peptidase (mitochondrial processing) beta, mRNA (cDNA
clone IMAGE:4309193), partial cds.
ACCESSION BC014079
VERSION BC014079.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1594)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1594)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC014079.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: l Column: 2.
FEATURES Location/Qualifiers
source 1..1594
/db_xref="H-InvDB:HIT000036507"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4309193"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1594
/gene="PMPCB"
/gene_synonym="MPP11"
/gene_synonym="MPPB"
/gene_synonym="MPPP52"
/db_xref="GeneID:9512"
/db_xref="MIM:603131"
CDS <1..1444
/gene="PMPCB"
/gene_synonym="MPP11"
/gene_synonym="MPPB"
/gene_synonym="MPPP52"
/codon_start=2
/product="PMPCB protein"
/protein_id="AAH14079.2"
/db_xref="GeneID:9512"
/db_xref="MIM:603131"
/translation="LSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVL
NVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFPEHMAFKGT
KKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEA
EIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLV
DYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIR
VRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCH
GNLCHSFQSFNTSYTDTGLWGLYMVCESSTVADMLHVVQKEWMRLCTSVTESEVARAR
NLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIY
NRSPAIAAVGPIKQLPDFKQIRSNMCWLRD"
misc_feature 176..619
/gene="PMPCB"
/gene_synonym="MPP11"
/gene_synonym="MPPB"
/gene_synonym="MPPP52"
/note="Peptidase_M16; Region: Insulinase (Peptidase family
M16)"
/db_xref="CDD:pfam00675"
misc_feature 632..1186
/gene="PMPCB"
/gene_synonym="MPP11"
/gene_synonym="MPPB"
/gene_synonym="MPPP52"
/note="Peptidase_M16_C; Region: Peptidase M16 inactive
domain. Peptidase M16 consists of two structurally related
domains. One is the active peptidase, whereas the other is
inactive. The two domains hold the substrate like a clamp"
/db_xref="CDD:pfam05193"
BASE COUNT 508 a 293 c 364 g 429 t
ORIGIN
1 gttgtcatcc gcggcgcggc ggcggctctg gggtttcagc gagagtcttc taatccgagg
61 cgctgcggga cggtcattat attttggaga gaacagatta agaagtacac aggctgctac
121 ccaagttgtt ctgaatgttc ctgaaacaag agtaacatgt ttagaaagtg gactcagagt
181 agcttcggaa gactctgggc tctcaacatg cacagttgga ctctggattg atgctggaag
241 tagatacgaa aatgagaaga acaatggaac agcacacttt ccggagcata tggctttcaa
301 gggcaccaag aagagatccc agttagatct ggaacttgag attgaaaata tgggtgctca
361 tctcaatgcc tatacctcca gagagcagac tgtatactat gccaaagcat tctctaaaga
421 cttgccaaga gctgtagaaa ttcttgctga tataatacaa aacagcacat tgggagaagc
481 agagattgaa cgtgagcgtg gagtaatcct tagagagatg caggaagttg aaaccaattt
541 acaagaagtt gtttttgatt atcttcatgc cacagcttat caaaatactg cacttggacg
601 gacaattttg ggaccaactg aaaatatcaa atctataagt cgtaaggact tagtggatta
661 tataaccaca cattataagg ggccaagaat agtgcttgct gctgctggag gtgtttccca
721 tgatgaattg cttgacttag caaagtttca tttcggtgac tctttatgca cacacaaagg
781 agaaatacca gctctgcctc cctgcaaatt cacaggaagt gagattcgtg tgagggatga
841 caagatgcct ttggcgcacc ttgcaatagc tgttgaagct gttggttggg cacatccaga
901 tacaatctgt ctcatggttg caaacacgct gattggcaac tgggatcgct cttttggggg
961 aggaatgaat ttatctagca agctggccca gctcacttgt catggcaatc tttgccatag
1021 ctttcagtct ttcaacactt cctacacaga tacaggatta tggggactgt atatggtttg
1081 tgaatcatcc actgttgcag acatgctaca tgttgttcaa aaagaatgga tgcgactctg
1141 tacaagtgtc acagaaagtg aggttgcacg agccagaaat cttctgaaaa caaacatgtt
1201 gttgcagctt gatggttcaa ctccaatttg tgaagatatt ggtaggcaaa tgttatgcta
1261 taatagaagg attcccatcc ctgagcttga agcaagaatt gatgctgtga atgctgagac
1321 aattcgagaa gtatgtacca aatacattta taataggagt ccagctattg ctgctgttgg
1381 tcccattaag caactaccag attttaaaca gatacgcagt aacatgtgtt ggcttcgtga
1441 ttaaaatgct cctaatcaag attgtttgaa cacatgtatt tataaaacag agctagagaa
1501 aaataaaaat gaacatgtat atacatttgg aaatttgaat taaatactgt atcatacttt
1561 caaaggataa aaagacaaaa aaaaaaaaaa aaaa
//