LOCUS BC013876 2318 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens optineurin, mRNA (cDNA clone MGC:10510 IMAGE:3831267),
complete cds.
ACCESSION BC013876
VERSION BC013876.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2318)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2318)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC013876.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: f Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56549110.
FEATURES Location/Qualifiers
source 1..2318
/db_xref="H-InvDB:HIT000036383"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10510 IMAGE:3831267"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2318
/gene="OPTN"
/gene_synonym="FIP2"
/gene_synonym="HIP7"
/gene_synonym="HYPL"
/gene_synonym="NRP"
/gene_synonym="TFIIIA-INTP"
/db_xref="GeneID:10133"
/db_xref="HGNC:HGNC:17142"
/db_xref="MIM:602432"
CDS 146..1879
/gene="OPTN"
/gene_synonym="FIP2"
/gene_synonym="HIP7"
/gene_synonym="HYPL"
/gene_synonym="NRP"
/gene_synonym="TFIIIA-INTP"
/codon_start=1
/product="optineurin"
/protein_id="AAH13876.1"
/db_xref="GeneID:10133"
/db_xref="HGNC:HGNC:17142"
/db_xref="MIM:602432"
/translation="MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQM
KELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSH
ENEKLKEELGKLKGKSERSSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGI
VSELQLKLNSSGSSEDSFVEIRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRS
ADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIET
QTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKC
QALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMT
HNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQT
IAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFED
GGRQSLMEMQSRHGARTSDSDQQAYLVQRGAEDRDWRQQRNIPIHSCPKCGEVLPDID
TLQIHVMDCII"
BASE COUNT 745 a 497 c 631 g 445 t
ORIGIN
1 ggctgccccc tccgccaccg ccgccgcccg ccggcaggtt ccctggtcag cgtcccatcc
61 cggtcgggag ttctctccag gcggcacgat gccgaggaaa cagtgaccct gagcgaagcc
121 aagccgggcg gcaggaactt ctgcaatgtc ccatcaacct ctcagctgcc tcactgaaaa
181 ggaggacagc cccagtgaaa gcacaggaaa tggacccccc cacctggccc acccaaacct
241 ggacacgttt accccggagg agctgctgca gcagatgaaa gagctcctga ccgagaacca
301 ccagctgaaa gaagccatga agctaaataa tcaagccatg aaagggagat ttgaggagct
361 ttcggcctgg acagagaaac agaaggaaga acgccagttt tttgagatac agagcaaaga
421 agcaaaagag cgtctaatgg ccttgagtca tgagaatgag aaattgaagg aagagcttgg
481 aaaactaaaa gggaaatcag aaaggtcatc tgaggacccc actgatgact ccaggcttcc
541 cagggccgaa gcggagcagg aaaaggacca gctcaggacc caggtggtga ggctacaagc
601 agagaaggca gacctgttgg gcatcgtgtc tgaactgcag ctcaagctga actccagcgg
661 ctcctcagaa gattcctttg ttgaaattag gatggctgaa ggagaagcag aagggtcagt
721 aaaagaaatc aagcatagtc ctgggcccac gagaacagtc tccactggca cggcattgtc
781 taaatatagg agcagatctg cagatggggc caagaattac ttcgaacatg aggagttaac
841 tgtgagccag ctcctgctgt gcctaaggga agggaatcag aaggtggaga gacttgaagt
901 tgcactcaag gaggccaaag aaagagtttc agattttgaa aagaaaacaa gtaatcgttc
961 tgagattgaa acccagacag aggggagcac agagaaagag aatgatgaag agaaaggccc
1021 ggagactgtt ggaagcgaag tggaagcact gaacctccag gtgacatctc tgtttaagga
1081 gcttcaagag gctcatacaa aactcagcga agctgagcta atgaagaaga gacttcaaga
1141 aaagtgtcag gcccttgaaa ggaaaaattc tgcaattcca tcagagttga atgaaaagca
1201 agagcttgtt tatactaaca aaaagttaga gctacaagtg gaaagcatgc tatcagaaat
1261 caaaatggaa caggctaaaa cagaggatga aaagtccaaa ttaactgtgc tacagatgac
1321 acacaacaag cttcttcaag aacataataa tgcattgaaa acaattgagg aactaacaag
1381 aaaagagtca gaaaaagtgg acagggcagt gctgaaggaa ctgagtgaaa aactggaact
1441 ggcagagaag gctctggctt ccaaacagct gcaaatggat gaaatgaagc aaaccattgc
1501 caagcaggaa gaggacctgg aaaccatgac catcctcagg gctcagatgg aagtttactg
1561 ttctgatttt catgctgaaa gagcagcgag agagaaaatt catgaggaaa aggagcaact
1621 ggcattgcag ctggcagttc tgctgaaaga gaatgatgct ttcgaagacg gaggcaggca
1681 gtccttgatg gagatgcaga gtcgtcatgg ggcgagaaca agtgactctg accagcaggc
1741 ttaccttgtt caaagaggag ctgaggacag ggactggcgg caacagcgga atattccgat
1801 tcattcctgc cccaagtgtg gagaggttct gcctgacata gacacgttac agattcacgt
1861 gatggattgc atcatttaag tgttgatgta tcacctcccc aaaactgttg gtaaatgtca
1921 gattttttcc tccaagagtt gtgcttttgt gttatttgtt ttcactcaaa tattttgcct
1981 cattattctt gttttaaaag aaagaaaaca ggccgggcac agtggctcat gcctgtaatc
2041 ccagcacttt gggaggtcga ggtgggtgga tcacttgggg tcagggtttg agaccagcct
2101 ggccaacatg gcggaaccct gtctctacca aaattacaaa aattagccga gcatggtggc
2161 gcatgcctgt agtcgcagct actcgcgagg ttgaggcagg agaattgctt gaacccagga
2221 agtggcagtt gcagtgagcc gagacgacac cactgcactc cagcctgggt gacagaggga
2281 gactctgtct cgaaagaaaa aaaaaaaaaa aaaaaaaa
//