LOCUS BC013737 4003 bp mRNA linear HUM 06-JAN-2005
DEFINITION Homo sapiens histone deacetylase 6, mRNA (cDNA clone MGC:5339
IMAGE:2984860), complete cds.
ACCESSION BC013737
VERSION BC013737.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4003)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4003)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (04-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: p Column: 3
This clone grew slowly and was rescued by PCR.
FEATURES Location/Qualifiers
source 1..4003
/db_xref="H-InvDB:HIT000036342"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5339 IMAGE:2984860"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4003
/gene="HDAC6"
/gene_synonym="HD6"
/gene_synonym="JM21"
/gene_synonym="KIAA0901"
/db_xref="GeneID:10013"
/db_xref="MIM:300272"
CDS 439..3630
/gene="HDAC6"
/gene_synonym="HD6"
/gene_synonym="JM21"
/gene_synonym="KIAA0901"
/codon_start=1
/product="HDAC6 protein"
/protein_id="AAH13737.1"
/db_xref="GeneID:10013"
/db_xref="MIM:300272"
/translation="METTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVD
AVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDV
HHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQV
GMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLL
MGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCAL
EALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYD
QNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEY
VGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGA
AVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAA
WHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIIL
ILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSL
RVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEEST
PGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQ
TTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTT
SEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPA
AGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAW
CYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH"
BASE COUNT 897 a 1167 c 1124 g 815 t
ORIGIN
1 gattccacca caaccaggca gcgaagaagt aggcagaacc cccagtcgcc ccctcaggac
61 tccagtgtca cttcgaagcg aaatattaaa aagggagccg ttccccgctc tatccccaat
121 ctagcggagg taaagaagaa aggcaaaatg aagaagctcg gccaagcaat ggaagaagac
181 ctaatcgtgg gactgcaagg gatggatctg aaccttgagg ctgaagcact ggctggcact
241 ggcttggtgt tggatgagca gttaaatgaa ttccattgcc tctgggatga cagcttcccg
301 gaaggccctg agcggctcca tgccatcaag gagcaactga tccaggaggg cctcctagat
361 cgctgcgtgt cctttcaggc ccggtttgct gaaaaggaag agctgatgtt ggttcacagc
421 ctagaatata ttgatctgat ggaaacaacc cagtacatga atgagggaga actccgtgtc
481 ctagcagaca cctacgactc agtttatctg catccgaact catactcctg tgcctgcctg
541 gcctcaggct ctgtcctcag gctggtggat gcggtcctgg gggctgagat ccggaatggc
601 atggccatca ttaggcctcc tggacatcac gcccagcaca gtcttatgga tggctattgc
661 atgttcaacc acgtggctgt ggcagcccgc tatgctcaac agaaacaccg catccggagg
721 gtccttatcg tagattggga tgtgcaccac ggtcaaggaa cacagttcac cttcgaccag
781 gaccccagtg tcctctattt ctccatccac cgctacgagc agggtaggtt ctggccccac
841 ctgaaggcct ctaactggtc caccacaggt ttcggccaag gccaaggata taccatcaat
901 gtgccttgga accaggtggg gatgcgggat gctgactaca ttgctgcttt cctgcacgtc
961 ctgctgccag tcgccctcga gttccagcct cagctggtcc tggtggctgc tggatttgat
1021 gccctgcaag gggaccccaa gggtgagatg gccgccactc cggcagggtt cgcccagcta
1081 acccacctgc tcatgggtct ggcaggaggc aagctgatcc tgtctctgga gggtggctac
1141 aacctccgcg ccctggctga aggcgtcagt gcttcgctcc acacccttct gggagaccct
1201 tgccccatgc tggagtcacc tggtgccccc tgccggagtg cccaggcttc agtttcctgt
1261 gctctggaag cccttgagcc cttctgggag gttcttgtga gatcaactga gaccgtggag
1321 agggacaaca tggaggagga caatgtagag gagagcgagg aggaaggacc ctgggagccc
1381 cctgtgctcc caatcctgac atggccagtg ctacagtctc gcacagggct ggtctatgac
1441 caaaatatga tgaatcactg caacttgtgg gacagccacc accctgaggt accccagcgc
1501 atcttgcgga tcatgtgccg tctggaggag ctgggccttg ccgggcgctg cctcaccctg
1561 acaccgcgcc ctgccacaga ggctgagctg ctcacctgtc acagtgctga gtacgtgggt
1621 catctccggg ccacagagaa aatgaaaacc cgggagctgc accgtgagag ttccaacttt
1681 gactccatct atatctgccc cagtaccttc gcctgtgcac agcttgccac tggcgctgcc
1741 tgccgcctgg tggaggctgt gctctcagga gaggttctga atggtgctgc tgtggtgcgt
1801 cccccaggac accacgcaga gcaggatgca gcttgcggtt tttgcttttt caactctgtg
1861 gctgtggctg ctcgccatgc ccagactatc agtgggcatg ccctacggat cctgattgtg
1921 gattgggatg tccaccacgg taatggaact cagcacatgt ttgaggatga ccccagtgtg
1981 ctatatgtgt ccctgcaccg ctatgatcat ggcaccttct tccccatggg ggatgagggt
2041 gccagcagcc agatcggccg ggctgcgggc acaggcttca ccgtcaacgt ggcatggaac
2101 gggccccgca tgggtgatgc tgactaccta gctgcctggc atcgcctggt gcttcccatt
2161 gcctacgagt ttaacccaga actggtgctg gtctcagctg gctttgatgc tgcacggggg
2221 gatccgctgg ggggctgcca ggtgtcacct gagggttatg cccacctcac ccacctgctg
2281 atgggccttg ccagtggccg cattatcctt atcctagagg gtggctataa cctgacatcc
2341 atctcagagt ccatggctgc ctgcactcgc tccctccttg gagacccacc acccctgctg
2401 accctgccac ggcccccact atcaggggcc ctggcctcaa tcactgagac catccaagtc
2461 catcgcagat actggcgcag cttacgggtc atgaaggtag aagacagaga aggaccctcc
2521 agttctaagt tggtcaccaa gaaggcaccc caaccagcca aacctaggtt agctgagcgg
2581 atgaccacac gagaaaagaa ggttctggaa gcaggcatgg ggaaagtcac ctcggcatca
2641 tttggggaag agtccactcc aggccagact aactcagaga cagctgtggt ggccctcact
2701 caggaccagc cctcagaggc agccacaggg ggagccactc tggcccagac catttctgag
2761 gcagccattg ggggagccat gctgggccag accacctcag aggaggctgt cgggggagcc
2821 actccggacc agaccacctc agaggagact gtgggaggag ccattctgga ccagaccacc
2881 tcagaggatg ctgttggggg agccacgctg ggccagacta cctcagagga ggctgtagga
2941 ggagctacac tggcccagac cacctcggag gcagccatgg agggagccac actggaccag
3001 actacgtcag aggaggctcc agggggcacc gagctgatcc aaactcctct agcctcgagc
3061 acagaccacc agaccccccc aacctcacct gtgcagggaa ctacacccca gatatctccc
3121 agtacactga ttgggagtct caggaccttg gagctaggca gcgaatctca gggggcctca
3181 gaatctcagg ccccaggaga ggagaaccta ctaggagagg cagctggagg tcaggacatg
3241 gctgattcga tgctgatgca gggatctagg ggcctcactg atcaggccat attttatgct
3301 gtgacaccac tgccctggtg tccccatttg gtggcagtat gccccatacc tgcagcaggc
3361 ctagacgtga cccaaccttg tggggactgt ggaacaatcc aagagaattg ggtgtgtctc
3421 tcttgctatc aggtctactg tggtcgttac atcaatggcc acatgctcca acaccatgga
3481 aattctggac acccgctggt cctcagctac atcgacctgt cagcctggtg ttactactgt
3541 caggcctatg tccaccacca ggctctccta gatgtgaaga acatcgccca ccagaacaag
3601 tttggggagg atatgcccca cccacactaa gccccagaat acggtccctc ttcaccttct
3661 gaggcccacg atagaccagc tgtagctcat tccagcctgt accttggatg aggggtagcc
3721 tcccactgca tcccatcctg aatatccttt gcaactcccc aagagtgctt atttaagtgt
3781 taatactttt aagagaactg cgacgattaa ttgtggatct ccccctgccc attgcctgct
3841 tgaggggcac cactactcca gcccagaagg aaaggggggc agctcagtgg ccccaagagg
3901 gagctgatat catgaggata acattggcgg gaggggagtt aactggcagg catggcaagg
3961 ttgcatatgt aataaagtac aagctgttaa aaaaaaaaaa aaa
//