LOCUS BC013142 1978 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interleukin 1, alpha, mRNA (cDNA clone MGC:9225
IMAGE:3875617), complete cds.
ACCESSION BC013142
VERSION BC013142.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1978)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1978)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC013142.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: p Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27894329.
FEATURES Location/Qualifiers
source 1..1978
/db_xref="H-InvDB:HIT000036146"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9225 IMAGE:3875617"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1978
/gene="IL1A"
/gene_synonym="IL-1A"
/gene_synonym="IL1-ALPHA"
/gene_synonym="IL1F1"
/db_xref="GeneID:3552"
/db_xref="HGNC:HGNC:5991"
/db_xref="MIM:147760"
CDS 10..825
/gene="IL1A"
/gene_synonym="IL-1A"
/gene_synonym="IL1-ALPHA"
/gene_synonym="IL1F1"
/codon_start=1
/product="interleukin 1, alpha"
/protein_id="AAH13142.1"
/db_xref="GeneID:3552"
/db_xref="HGNC:HGNC:5991"
/db_xref="MIM:147760"
/translation="MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLH
EGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIAN
DSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNL
DEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSE
TNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA"
BASE COUNT 640 a 395 c 360 g 583 t
ORIGIN
1 gaagtcaaga tggccaaagt tccagacatg tttgaagacc tgaagaactg ttacagtgaa
61 aatgaagaag acagttcctc cattgatcat ctgtctctga atcagaaatc cttctatcat
121 gtaagctatg gcccactcca tgaaggctgc atggatcaat ctgtgtctct gagtatctct
181 gaaacctcta aaacatccaa gcttaccttc aaggagagca tggtggtagt agcaaccaac
241 gggaaggttc tgaagaagag acggttgagt ttaagccaat ccatcactga tgatgacctg
301 gaggccatcg ccaatgactc agaggaagaa atcatcaagc ctaggtcagc accttttagc
361 ttcctgagca atgtgaaata caactttatg aggatcatca aatacgaatt catcctgaat
421 gacgccctca atcaaagtat aattcgagcc aatgatcagt acctcacggc tgctgcatta
481 cataatctgg atgaagcagt gaaatttgac atgggtgctt ataagtcatc aaaggatgat
541 gctaaaatta ccgtgattct aagaatctca aaaactcaat tgtatgtgac tgcccaagat
601 gaagaccaac cagtgctgct gaaggagatg cctgagatac ccaaaaccat cacaggtagt
661 gagaccaacc tcctcttctt ctgggaaact cacggcacta agaactattt cacatcagtt
721 gcccatccaa acttgtttat tgccacaaag caagactact gggtgtgctt ggcagggggg
781 ccaccctcta tcactgactt tcagatactg gaaaaccagg cgtaggtctg gagtctcact
841 tgtctcactt gtgcagtgtt gacagttcat atgtaccatg tacatgaaga agctaaatcc
901 tttactgtta gtcatttgct gagcatgtac tgagccttgt aattctaaat gaatgtttac
961 actctttgta agagtggaac caacactaac atataatgtt gttatttaaa gaacacccta
1021 tattttgcat agtaccaatc attttaatta ttattcttca taacaatttt aggaggacca
1081 gagctactga ctatggctac caaaaagact ctacccatat tacagatggg caaattaagg
1141 cataagaaaa ctaagaaata tgcacaatag cagttgaaac aagaagccac agacctagga
1201 tttcatgatt tcatttcaac tgtttgcctt ctacttttaa gttgctgatg aactcttaat
1261 caaatagcat aagtttctgg gacctcagtt ttatcatttt caaaatggag ggaataatac
1321 ctaagccttc ctgccgcaac agttttttat gctaatcagg gaggtcattt tggtaaaata
1381 cttcttgaag ccgagcctca agatgaaggc aaagcacgaa atgttatttt ttaattatta
1441 tttatatatg tatttataaa tatatttaag ataattataa tatactatat ttatgggaac
1501 cccttcatcc tctgagtgtg accaggcatc ctccacaata gcagacagtg ttttctggga
1561 taagtaagtt tgatttcatt aatacagggc attttggtcc aagttgtgct tatcccatag
1621 ccaggaaact ctgcattcta gtacttggga gacctgtaat catataataa atgtacatta
1681 attaccttga gccagtaatt ggtccgatct ttgactcttt tgccattaaa cttacctggg
1741 cattcttgtt tcaattccac ctgcaatcaa gtcctacaag ctaaaattag atgaactcaa
1801 ctttgacaac catgagacca ctgttatcaa aactttcttt tctggaatgt aatcaatgtt
1861 tcttctaggt tctaaaaatt gtgatcagac cataatgtta cattattatc aacaatagtg
1921 attgatagag tgttatcagt cataactaaa taaagcttgc aacaaaaaaa aaaaaaaa
//