LOCUS BC012855 2130 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens leucine rich transmembrane and 0-methyltransferase
domain containing, mRNA (cDNA clone MGC:9830 IMAGE:3863323),
complete cds.
ACCESSION BC012855
VERSION BC012855.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2130)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2130)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 21 Row: h Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21687174.
FEATURES Location/Qualifiers
source 1..2130
/db_xref="H-InvDB:HIT000035999"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9830 IMAGE:3863323"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_66"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2130
/gene="LRTOMT"
/gene_synonym="COMT2"
/gene_synonym="LRTOMT1"
/gene_synonym="LRTOMT2"
/db_xref="GeneID:220074"
/db_xref="HGNC:HGNC:25033"
/db_xref="MIM:612414"
CDS 167..745
/gene="LRTOMT"
/gene_synonym="COMT2"
/gene_synonym="LRTOMT1"
/gene_synonym="LRTOMT2"
/codon_start=1
/product="leucine rich transmembrane and
0-methyltransferase domain containing"
/protein_id="AAH12855.1"
/db_xref="GeneID:220074"
/db_xref="HGNC:HGNC:25033"
/db_xref="MIM:612414"
/translation="MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRS
KSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFF
NLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFD
FSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL"
BASE COUNT 517 a 567 c 494 g 552 t
ORIGIN
1 ccaagactgg agaggaagcg actgcgggga gtatttccat tttaaccgga aacaatccct
61 gaacccacag gaatgaatgc ctaatggtgg agtttcagcc atcagtgaca ggctgaaccc
121 agactcccag ggcacctgct tgcacctttg aatgatggcc tgaactatga acaaacggga
181 ctatatgaac acttcggtac aggagccccc tcttgactac tccttcagaa gcatccacgt
241 cattcaagat ctggtaaatg aggagccaag gacaggacta cgaccactga agcgttcaaa
301 gtcggggaaa tcactgaccc agtccctgtg gctgaataac aatgttctca atgatctgag
361 agacttcaac caggtggctt cacagctgtt ggagcaccca gagaacctgg cctggatcga
421 cctgtccttt aatgacctga cttccattga ccctgtccta acaactttct tcaacctgag
481 tgtcctctat cttcacggca acagcatcca gcgcctgggg gaggtgaata agctggctgt
541 ccttcctcgg ctccgtagcc tgacactcca tgggaacccc atggaggaag agaaagggta
601 taggcaatat gtgctgtgca ccctgtcccg tatcaccacg ttcgacttca gtggggtcac
661 caaagcagac cgcaccacag ctgaagtctg gaaacgcatg aacatcaagc ccaagaaggc
721 ctggaccaag cagaatacac tttgaggctc ccacgaccct agtagtccta aaggcctaag
781 catagacagc atggtttgac aataaataat ttgagctgtt gagcagatga gaagtcactt
841 acaccttgta gagatgttct ctaactcagg caactgcaag tagctctagc cttttctttt
901 cttttttttt tttttgagac ggagtctcac tctgtcacac aggctggagt gcagtggcac
961 gatcttggct cactgcaacc tcagcctccc aggttcaaga gattctcctg cctcagcctc
1021 cccagtagct gtgattaaag gcgcctgcca ccatgactgg ctaattttgt tgttgttgtt
1081 gttgttttga gacggtttca ctcgtcaccc cagctggagt gcagtggtgc gatctcagct
1141 cactgcaacc tccgcctgct gggttcaagc gattctcctg cctcagcctc ctgagtagct
1201 gggattacag gcgcctgcta ccacatccag ctaatttttt tttttgagac ggagtctcgc
1261 tctgtcaccc aggctggagt gcagtggcac gatctcggct cactgcaaac tccgccttcc
1321 aggttcacgc cattctcctg cctcagcctc ccaagtagct gggactatag gcacctacta
1381 ccacgcctgg ctaatttttt gtatttttag tagagacggg gtttcaccat gttagccagg
1441 atggtctcca tctcctgacc ttgtgatcca cccacctcgg cttcccccag ctaatttttt
1501 atattttagt agagacaagg tttcgccatg ttggccaggc tggtcttgaa ctcctgacct
1561 caggtgatcc gtctgctttg gcctcccaaa gtgctgggat tagaagcgtg agccaccacg
1621 cccagccttt ttttgtattt ttagtagaga tggggtttcg ccatgttggc caggctggtc
1681 tcaaactcct gacctcaggt gatctgccca cctcagcctc ccaaagtgct aggattacag
1741 gataagccac tgcacctggc cagctctagt cttattttgc tgaaaaaggg aggcaattga
1801 gggaaaggcc tgctggcctg ggacactgga gacgtgggtt taccacacag ccttgggaaa
1861 tttatctaac tctctgggcc cctttgtact tttcagctta gagatttggg ggttaaagta
1921 gatcagtaat ttccaaactc ttcacagagt accagggtct gtagagatgc ctcacaggcc
1981 tccatgacag gccaagaaga tggcctatga tctctgaaac cagcccccac ttcaatcaga
2041 tcaaagtaat tccattctgt tttatatgct gggattctgc ttaagatttc atttgataaa
2101 aagaatcttc tgcttaaaaa aaaaaaaaaa
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