LOCUS BC012737 3760 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens chloride channel 7, mRNA (cDNA clone MGC:15192
IMAGE:4026193), complete cds.
ACCESSION BC012737
VERSION BC012737.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3760)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3760)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC012737.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 25 Row: n Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39725672.
FEATURES Location/Qualifiers
source 1..3760
/db_xref="H-InvDB:HIT000035923"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15192 IMAGE:4026193"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3760
/gene="CLCN7"
/gene_synonym="CLC-7"
/gene_synonym="CLC7"
/gene_synonym="OPTA2"
/db_xref="GeneID:1186"
/db_xref="HGNC:HGNC:2025"
/db_xref="MIM:602727"
CDS 38..2455
/gene="CLCN7"
/gene_synonym="CLC-7"
/gene_synonym="CLC7"
/gene_synonym="OPTA2"
/codon_start=1
/product="chloride channel 7"
/protein_id="AAH12737.1"
/db_xref="GeneID:1186"
/db_xref="HGNC:HGNC:2025"
/db_xref="MIM:602727"
/translation="MANVSKKVSWSGRDRDDEEAAPLLRRTARPGGGTPLLNGAGPGA
ARQSPRSALFRVGHMSSVELDDELLDPDMDPPHPFPKEIPHNEKLLSLKYESLDYDNS
ENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAGLKYRVIK
GNIDKFTEKGGLSFSLLLWATLNAAFVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKI
PHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIF
EYFRRDTEKRDFVSAGAAAGVSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMIS
TFTLNFVLSIYHGNMWDLSSPGLINFGRFDSEKMAYTIHEIPVFIAMGVVGGVLGAVF
NALNYWLTMFRIRYIHRPCLQVIEAVLVAAVTATVAFVLIYSSRDCQPLQGGSMSYPL
QLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLT
VSAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSL
TVIMMEATSNVTYGFPIMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLHWEAPVTSHS
LTAREVMSTPVTCLRRREKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRS
QLIVLLKHKVFVERSNLGLVQRRLRLKDFRDAYPRFPPIQSIHVSQDERECTMDLSEF
MNPSPYTVPQEASLPRVFKLFRALGLRHLVVVDNRNQVVGLVTRKDLARYRLGKRGLE
ELSLAQT"
BASE COUNT 638 a 1214 c 1179 g 729 t
ORIGIN
1 ccggcgcttc ccggccggtg tcgctccgcg gcgggccatg gccaacgtct ctaagaaggt
61 gtcctggtcc ggccgggacc gggacgacga ggaggcggcg ccgctgctgc ggaggacggc
121 gcggcccggc ggggggacgc cgctgctgaa cggggctggg cctggggctg cgcgccagtc
181 accacgttct gcgcttttcc gagtcggaca tatgagcagc gtggagctgg atgatgaact
241 tttggacccg gatatggacc ctccacatcc cttccccaag gagatcccac acaacgagaa
301 gctcctgtcc ctcaagtatg agagcttgga ctatgacaac agtgagaacc agctgttcct
361 ggaggaggag cggcggatca atcacacggc cttccggacg gtggagatca agcgctgggt
421 catctgcgcc ctcattggga tcctcacggg cctcgtggcc tgcttcattg acatcgtggt
481 ggaaaacctg gctggcctca agtacagggt catcaagggc aatatcgaca agttcacaga
541 gaagggcgga ctgtccttct ccctgttgct gtgggccacg ctgaacgccg ccttcgtgct
601 cgtgggctct gtgattgtgg ctttcataga gccggtggct gctggcagcg gaatccccca
661 gatcaagtgc ttcctcaacg gggtgaagat cccccacgtg gtgcggctca agacgttggt
721 gatcaaagtg tccggtgtga tcctgtccgt ggtcgggggc ctggccgtgg gaaaggaagg
781 gccgatgatc cactcaggtt cagtgattgc cgccgggatc tctcagggaa ggtcaacgtc
841 actgaaacga gatttcaaga tcttcgagta cttccgcaga gacacagaga agcgggactt
901 cgtctccgca ggggctgcgg ccggagtgtc agcggcgttt ggagcccccg tgggtggggt
961 cctgttcagc ttggaggagg gtgcgtcctt ctggaaccag ttcctgacct ggaggatctt
1021 ctttgcttcc atgatctcca cgttcaccct gaattttgtt ctgagcattt accacgggaa
1081 catgtgggac ctgtccagcc caggcctcat caacttcgga aggtttgact cggagaaaat
1141 ggcctacacg atccacgaga tcccggtctt catcgccatg ggcgtggtgg gcggtgtgct
1201 tggagcagtg ttcaatgcct tgaactactg gctgaccatg tttcgaatca ggtacatcca
1261 ccggccctgc ctgcaggtga ttgaggccgt gctggtggcc gccgtcacgg ccacagttgc
1321 cttcgtgctg atctactcgt cgcgggattg ccagcccctg caggggggct ccatgtccta
1381 cccgctgcag ctcttttgtg cagatggcga gtacaactcc atggctgcgg ccttcttcaa
1441 caccccggag aagagcgtgg tgagcctctt ccacgacccg ccaggctcct acaaccccct
1501 gaccctcggc ctgttcacgc tggtctactt cttcctggcc tgctggacct acgggctcac
1561 ggtgtctgcc ggggtcttca tcccgtccct gctcatcggg gctgcctggg gccggctctt
1621 tgggatctcc ctgtcctacc tcacgggggc ggcgatctgg gcggaccccg gcaaatacgc
1681 cctgatggga gctgctgccc agctgggcgg gattgtgcgg atgacactga gcctgaccgt
1741 catcatgatg gaggccacca gcaacgtgac ctacggcttc cccatcatgc tggtgctcat
1801 gaccgccaag atcgtgggcg acgtcttcat tgagggcctg tacgacatgc acattcagct
1861 gcagagtgtg cccttcctgc actgggaggc cccggtcacc tcacactcac tcactgccag
1921 ggaggtgatg agcacaccag tgacctgcct gaggcggcgt gagaaggtcg gcgtcattgt
1981 ggacgtgctg agcgacacgg cgtccaatca caacggcttc cccgtggtgg agcatgccga
2041 tgacacccag cctgcccggc tccagggcct gatcctgcgc tcccagctca tcgttctcct
2101 aaagcacaag gtgtttgtgg agcggtccaa cctgggcctg gtacagcggc gcctgaggct
2161 gaaggacttc cgagacgcct acccgcgctt cccacccatc cagtccatcc acgtgtccca
2221 ggacgagcgg gagtgcacca tggacctctc cgagttcatg aacccctccc cctacacggt
2281 gccccaggag gcgtcgctcc cacgggtgtt caagctgttc cgggccctgg gcctgcggca
2341 cctggtggtg gtggacaacc gcaatcaggt tgtcgggttg gtgaccagga aggacctcgc
2401 caggtaccgc ctgggaaaga gaggcttgga ggagctctcg ctggcccaga cgtgaggccc
2461 agccctgccc ataatgggca ctggcgctgg caccccggcc cttctgcatt tcctcccgga
2521 gtcactggtt tctcggccca aaccatgctc cccagcagtg gcaatggcga gcaccctgca
2581 gctgggcggg caggcggcag gcgcggaact gaccctctcg cgggactgac cctgttgtgg
2641 gcagtggtct ccccccttgg cgcctccttg cgcaggccca gcctccactc tcctcgtcta
2701 ggtttcttta cctccaggga tcagctgtgt gtgtgtgacc tccctaccgg gctatcggcc
2761 tcttgggagc cagcggcagg gccggcacct gcgtgcctgt gcccgtgtgc gtgagacaga
2821 gcccttgccc ctgctgctgc cccgagggct gccctgccct ggaagggccc ctctgcctcc
2881 acaccagtgg agtcttcgag acttgggagc tgcttggcct cattttcagc catgagcaga
2941 cggcctgtgg tccctgggcc tgaggcacgg actcgtagca ccagggtttg gaggctgcga
3001 ccgccccgga gagcagcttc acactggcgc cacagaggag ccccacgtgc actccccggc
3061 ctgcatccgg cttgggtaca cgggcccaga ggactggggt gactcacggg ccctgtgctg
3121 tgatgttgag agctgagaaa aacctccaag gccctgagcc ccatgcccag ccctgccttg
3181 gtcccccaac ccccagagct tggagtctgg gccccacacc cagccctgcc ttggtccctg
3241 agcctcagag cgtggaattg ctgccctgtg gacactggct gggaaggcag gtcttcccct
3301 agcacatggg gaccccggcc tcgagggtga cctccctacc ttgcccctgc cagccaccaa
3361 gcgcaggtgc agcgggggcc agactcctgc cggcctcaga ggacacctgg cccagcacag
3421 gcagctagaa gggccggtgg gcaccggggc cgggaagccc ccacctcacc acctgagggc
3481 ccctgggagg ctcctctggc ctggctgggc tgggtctggg gccgccacag gcccctcacg
3541 gggcggcaga ggcaacttca gtgtccctgt tagagcaaca cgggtccctc cgtggggggc
3601 tgggtgcggc cccctgccgt gtatttcctc cccagggagt ggggcctccc cgggagctga
3661 cgccaccacc ctgcttagcc ctcacagggc cccaaggtgt ccgagtgtgt tgggtctgaa
3721 cgcgaaataa agaaatcctc tcaaaaaaaa aaaaaaaaaa
//