LOCUS BC012114 2071 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma, mRNA (cDNA clone MGC:20127 IMAGE:4651870),
complete cds.
ACCESSION BC012114
VERSION BC012114.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2071)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2071)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: o Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361093.
FEATURES Location/Qualifiers
source 1..2071
/db_xref="H-InvDB:HIT000035669"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20127 IMAGE:4651870"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2071
/gene="IKBKG"
/gene_synonym="FIP-3"
/gene_synonym="FIP3"
/gene_synonym="Fip3p"
/gene_synonym="IKK-gamma"
/gene_synonym="IP"
/gene_synonym="IP2"
/gene_synonym="NEMO"
/db_xref="GeneID:8517"
/db_xref="MIM:300248"
CDS 225..1484
/gene="IKBKG"
/gene_synonym="FIP-3"
/gene_synonym="FIP3"
/gene_synonym="Fip3p"
/gene_synonym="IKK-gamma"
/gene_synonym="IP"
/gene_synonym="IP2"
/gene_synonym="NEMO"
/codon_start=1
/product="IKBKG protein"
/protein_id="AAH12114.1"
/db_xref="GeneID:8517"
/db_xref="MIM:300248"
/translation="MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSE
QGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARK
LVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRL
EAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQ
AASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVA
KQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLE
QLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEP
PDFCCPKCQYQAPDMDTLQIHVMECIE"
BASE COUNT 449 a 604 c 656 g 362 t
ORIGIN
1 cctgaacgcc catcaagccc atggcccttg tgatccaggt ggggaaacta aggcccagag
61 aagtgaggac cccgcagact atcaatccca gtctcttccc ctcactccct gtgaagctct
121 ccagcatcat cgaggtccca tcaggtgggg aaggatgctg ttccaggcgc acactagtct
181 acaaggccag agctttctgg aagggggcac ccttgccctg ttggatgaat aggcacctct
241 ggaagagcca actgtgtgag atggtgcagc ccagtggtgg cccggcagca gatcaggacg
301 tactgggcga agagtctcct ctggggaagc cagccatgct gcacctgcct tcagaacagg
361 gcgctcctga gaccctccag cgctgcctgg aggagaatca agagctccga gatgccatcc
421 ggcagagcaa ccagattctg cgggagcgct gcgaggagct tctgcatttc caagccagcc
481 agagggagga gaaggagttc ctcatgtgca agttccagga ggccaggaaa ctggtggaga
541 gactcggcct ggagaagctc gatctgaaga ggcagaagga gcaggctctg cgggaggtgg
601 agcacctgaa gagatgccag cagcagatgg ctgaggacaa ggcctctgtg aaagcccagg
661 tgacgtcctt gctcggggag ctgcaggaga gccagagtcg cttggaggct gccactaagg
721 aatgccaggc tctggagggt cgggcccggg cggccagcga gcaggcgcgg cagctggaga
781 gtgagcgcga ggcgctgcag cagcagcaca gcgtgcaggt ggaccagctg cgcatgcagg
841 gccagagcgt ggaggccgcg ctccgcatgg agcgccaggc cgcctcggag gagaagagga
901 agctggccca gttgcaggtg gcctatcacc agctcttcca agaatacgac aaccacatca
961 agagcagcgt ggtgggcagt gagcggaagc gaggaatgca gctggaagat ctcaaacagc
1021 agctccagca ggccgaggag gccctggtgg ccaaacagga ggtgatcgat aagctgaagg
1081 aggaggccga gcagcacaag attgtgatgg agaccgttcc ggtgctgaag gcccaggcgg
1141 atatctacaa ggcggacttc caggctgaga ggcaggcccg ggagaagctg gccgagaaga
1201 aggagctcct gcaggagcag ctggagcagc tgcagaggga gtacagcaaa ctgaaggcca
1261 gctgtcagga gtcggccagg atcgaggaca tgaggaagcg gcatgtcgag gtctcccagg
1321 cccccttgcc ccccgcccct gcctacctct cctctcccct ggccctgccc agccagagga
1381 ggagcccccc cgaggagcca cctgacttct gctgtcccaa gtgccagtat caggcccctg
1441 atatggacac cctgcagata catgtcatgg agtgcattga gtagggccgg ccagtgcaag
1501 gccactgcct gccgaggacg tgcccgggac cgtgcagtct gcgctttcct ctcccgcctg
1561 cctagcccag gatgaagggc tgggtggcca caactgggat gccacctgga gccccaccca
1621 ggagctggcc gcggcacctt acgcttcagc tgttgatccg ctggtcccct cttttggggt
1681 agatgcggcc ccgatcaggc ctgactcgct gctctttttg ttcccttctg tctgctcgaa
1741 ccacttgcct cgggctaatc cctccctctt cctccacccg gcactgggga agtcaagaat
1801 ggggcctggg gctctcaggg agaactgctt cccctggcag agctgggtgg cagctcttcc
1861 tcccaccgga caccgacccg cccgctgctg tgccctggga gtgctgccct cttaccatgc
1921 acacgggtgc tctccttttg ggctgcatgc tattccattt tgcagccaga ccgatgtgta
1981 tttaaccagt cactattgat ggacatttgg gttgtttccc atctttttgt taccataaat
2041 aatggcatag taaaaaaaaa aaaaaaaaaa a
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