LOCUS BC012106 1160 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens major histocompatibility complex, class II, DQ beta 1,
mRNA (cDNA clone MGC:20093 IMAGE:4574913), complete cds.
ACCESSION BC012106
VERSION BC012106.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1160)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1160)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: h Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24797068.
FEATURES Location/Qualifiers
source 1..1160
/db_xref="H-InvDB:HIT000035663_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20093 IMAGE:4574913"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1160
/gene="HLA-DQB1"
/gene_synonym="CELIAC1"
/gene_synonym="HLA-DQB"
/gene_synonym="IDDM1"
/db_xref="GeneID:3119"
/db_xref="MIM:604305"
CDS 55..840
/gene="HLA-DQB1"
/gene_synonym="CELIAC1"
/gene_synonym="HLA-DQB"
/gene_synonym="IDDM1"
/codon_start=1
/product="HLA-DQB1 protein"
/protein_id="AAH12106.1"
/db_xref="GeneID:3119"
/db_xref="MIM:604305"
/translation="MSWKKALRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFK
GMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLER
TRAELDTVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIK
VRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIV
EWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGLLH"
misc_feature 184..420
/gene="HLA-DQB1"
/gene_synonym="CELIAC1"
/gene_synonym="HLA-DQB"
/gene_synonym="IDDM1"
/note="MHC_II_beta; Region: Class II histocompatibility
antigen, beta domain"
/db_xref="CDD:pfam00969"
misc_feature 484..699
/gene="HLA-DQB1"
/gene_synonym="CELIAC1"
/gene_synonym="HLA-DQB"
/gene_synonym="IDDM1"
/note="IGc1; Region: Immunoglobulin C-Type"
/db_xref="CDD:smart00407"
BASE COUNT 252 a 339 c 315 g 254 t
ORIGIN
1 atccatcagg tccaagctgt gttgactacc actacttttc ccttcgtctc aattatgtct
61 tggaagaagg ctttgcggat ccctggaggc cttcgggtag caactgtgac cttgatgctg
121 gcgatgctga gcaccccggt ggctgagggc agagactctc ccgaggattt cgtgtaccag
181 tttaagggca tgtgctactt caccaacggg acggagcgcg tgcgtcttgt gaccagatac
241 atctataacc gagaggagta cgcacgcttc gacagcgacg tgggggtgta tcgggcggtg
301 acgccgctgg ggccgcctgc cgccgagtac tggaacagcc agaaggaagt cctggagagg
361 acccgggcgg agttggacac ggtgtgcaga cacaactacc agttggagct ccgcacgacc
421 ttgcagcggc gagtggagcc cacagtgacc atctccccat ccaggacaga ggccctcaac
481 caccacaacc tgctggtctg ctcagtgaca gatttctatc cagcccagat caaagtccgg
541 tggtttcgga atgaccagga ggagacaact ggcgttgtgt ccacccccct tattaggaac
601 ggtgactgga ccttccagat cctggtgatg ctggaaatga ctccccagcg tggagacgtc
661 tacacctgcc acgtggagca ccccagcctc cagaacccca tcatcgtgga gtggcgggct
721 cagtctgaat ctgcccagag caagatgctg agtggcattg gaggcttcgt gctggggctg
781 atcttcctcg ggctgggcct tattatccat cacaggagtc agaaagggct cctgcactga
841 ctcctgagac tattttaact gggattggtt atcacttttc tgtaacgcct gcttgtccct
901 gcccagaatt cccagctgcc tgtgtcagcc tgtccccctg agatcagagt cctacagtgg
961 ctgtcacgca gccaccaggt catctccttt catccccacc tcgaggctga tggctgtgac
1021 cctgcttcct gcacttaccc agagcctctg cctgtgcacg gccagctgcg tctactgagg
1081 ccccaagggg tttctgtttc tattctctcc tcagactgct caagagaagc acatgaaaac
1141 caaaaaaaaa aaaaaaaaaa
//