LOCUS BC012097 3082 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens oculocutaneous albinism II, mRNA (cDNA clone MGC:20070
IMAGE:4641135), complete cds.
ACCESSION BC012097
VERSION BC012097.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3082)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3082)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: l Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557810.
FEATURES Location/Qualifiers
source 1..3082
/db_xref="H-InvDB:HIT000035656"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20070 IMAGE:4641135"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3082
/gene="OCA2"
/gene_synonym="BEY"
/gene_synonym="BEY1"
/gene_synonym="BEY2"
/gene_synonym="BOCA"
/gene_synonym="EYCL"
/gene_synonym="HCL3"
/gene_synonym="PED"
/gene_synonym="SHEP1"
/db_xref="GeneID:4948"
/db_xref="HGNC:HGNC:8101"
/db_xref="MIM:611409"
CDS 111..2555
/gene="OCA2"
/gene_synonym="BEY"
/gene_synonym="BEY1"
/gene_synonym="BEY2"
/gene_synonym="BOCA"
/gene_synonym="EYCL"
/gene_synonym="HCL3"
/gene_synonym="PED"
/gene_synonym="SHEP1"
/codon_start=1
/product="OCA2 protein"
/protein_id="AAH12097.1"
/db_xref="GeneID:4948"
/db_xref="HGNC:HGNC:8101"
/db_xref="MIM:611409"
/translation="MHLEGRDGRRYPGAPAVELLQTSVPSGLAELVAGKRRLPRGAGG
ADPSHSCPRGAAGQSSWAPAGQEFASFLTKGRSHSSLPQMSSSRSKDSCFTENTPLLR
NSLQEKGSRCIPVYHPEFITAEESWEDSSADWERRYLLSREVSGLSASASSEKGDLLD
SPHIRLRLSKLRRCVQWLKVMGLFAFVVLCSILFSLYPDQGKLWQLLALSPLENYSVN
LSSHVDSTLLQVDLAGALVASGPSRPGREEHIVVELTQADALGSRWRRPQQVTHNWTV
YLNPRRSEHSVMSRTFEVLTRETVSISIRASLQQTQAVPLLMAHQYLRGSVETQVTIA
TAILAGVYALIIFERPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYR
LSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIF
TNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYW
NRKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRRLLLGKVLALEHLLARRL
HTFHRQISQEDKNWETNIQELQKKHRISDGILLAKCLTVLGFVIFMFFLNSFVPGIHL
DLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALAHLHLIEYVGE
QTALLIKMVPEEQRLIAAIVLVVWVSALASSLIDNIPFTATMIPVLLNLSHDPEVGLP
APPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCT
VGMCYLLVAHVVVGWN"
BASE COUNT 713 a 789 c 800 g 780 t
ORIGIN
1 cttacttcga aggctgtgct ccgctcacca tccagagcgg aggtgcggac cttaaactca
61 ctcctggaga aagatctgca agtgcgcaga gagaagactg gcagtggagc atgcatctgg
121 agggcagaga cggcaggcgg taccccggcg cgccggcggt ggagctcctg cagacgtccg
181 tgcccagcgg actcgctgaa cttgtggccg gcaagcgcag gcttcctcgg ggagccggtg
241 gagctgaccc ctcgcactcc tgccccaggg gggctgccgg gcagagctct tgggctcctg
301 caggccagga gtttgcttca ttcctcacaa aagggaggtc tcactcttct ttgccccaga
361 tgtccagctc caggtctaaa gattcctgct ttacagaaaa cactcctttg ctgaggaatt
421 ccttacagga gaaagggtca cggtgcatac ctgtttacca tccagagttc atcactgctg
481 aagagtcttg ggaagacagc tctgctgact gggagcgaag atacctgcta agcagggagg
541 tgtctggtct gtctgcatct gcctcctccg agaagggaga ccttctggac agcccgcaca
601 tccgactccg tctttccaag ctgaggcgct gtgtgcagtg gctgaaagtc atgggcctgt
661 ttgcctttgt ggtgctgtgt tctattttgt tcagcctata tccggatcaa ggaaagctct
721 ggcagctgtt ggccttatca ccgctggaga actactccgt gaaccttagc agccacgtgg
781 actccacgct gctgcaggtg gacctggcag gggccctagt ggccagtggg ccgagtcgtc
841 ctgggaggga agagcacatc gtggtggagc tgacccaggc tgacgctttg ggctccaggt
901 ggcggcggcc acagcaggtc actcacaact ggacggtgta tttaaatccg aggagaagcg
961 agcactcagt gatgagcagg acctttgagg tactgaccag agagacggtg tccatcagca
1021 tccgggcctc cctgcagcag acccaggctg tccctctttt gatggctcat cagtacctcc
1081 gcggaagtgt agaaacccag gtgaccatcg cgacggccat cctcgcgggc gtctacgcgc
1141 tgatcatatt tgagagaccc agcctgaccc atgtggtgga gtggattgat tttgagacgc
1201 tggccctgct gtttggcatg atgatcttag tagccatatt ttcagaaacg ggatttttcg
1261 attattgtgc tgtaaaggca taccggctct cccggggacg ggtgtgggcc atgatcatca
1321 tgctctgtct catcgcggcc gtcctctctg ccttcttgga caacgtcacc accatgctcc
1381 tcttcacgcc tgtgaccata aggttgtgtg aggtgctcaa ccttgatcca agacaagtcc
1441 tgattgcaga agtgatcttc acaaacattg gaggagctgc cactgccatc ggggaccctc
1501 caaatgtcat tattgtttcc aaccaagagc tgaggaagat gggcctggac tttgccggat
1561 tcactgcaca catgttcatt gggatttgtc ttgttctcct ggtctgcttt ccgctcctca
1621 gactccttta ctggaacaga aagctttata acaaggaacc cagtgagatt gttgaactga
1681 agcacgagat tcacgtctgg cgcctgactg ctcagcgcat cagcccggcc agccgcgagg
1741 agacagctgt gcgccgcctg ctgctgggga aggtgctggc actggagcac ctgctcgccc
1801 ggaggctgca caccttccac agacagatct cacaggagga caaaaattgg gagaccaata
1861 tccaagaact ccaaaaaaag cataggatat ctgacgggat tctgctcgcc aaatgcctga
1921 cagtgttggg atttgttatc ttcatgtttt tcctcaattc gtttgtccct ggcattcatc
1981 ttgatcttgg atggattgct attctgggtg ccatctggtt gctaatttta gctgatattc
2041 atgattttga gataattcta cacagagtgg aatgggcaac ccttctgttt tttgcagcgc
2101 tctttgttct gatggaggca ttggcacatc tccacttaat agaatatgtt ggagaacaaa
2161 ctgctttgct aataaagatg gtcccagagg agcagcgcct catagccgcc attgtcctgg
2221 tggtgtgggt ctcagccctg gcgtcgtccc tgattgacaa catcccgttc actgctacca
2281 tgattcccgt gctcctgaac ctgagccacg accctgaggt tggcctgccc gcaccgccgc
2341 tcatgtatgc cctggccttc ggtgcttgcc tgggaggtaa cgggacactg attggcgcgt
2401 cagcaaacgt cgtgtgtgca gggattgcag aacagcatgg atatgggttc tccttcatgg
2461 aatttttcag gctgggcttc ccaatgatgg ttgtgtcctg cactgttggg atgtgttatc
2521 tccttgtggc tcatgtggtg gtgggatgga attaatagac atccatctat tgctcgaaga
2581 ctaaaggaaa cttcatccat cacaacccat tagtcataaa actaccctga ccccactgtt
2641 tgaagaagaa aaggtgctta ccctggagat gctacagaga cacagtggaa tagaccttga
2701 cactaacact ctaattcaag cgaatgttgg aacaccatga cctcctctgt gtgtcctttc
2761 tccccaagga caaaatgtag aaagatgtga gataacttac tcaagattcc cctccagaaa
2821 aatacgtatg tttaaaaacc cttcctgcta tacataggaa aagacacaca tccacctaaa
2881 attgactgta ctgtttaact gtcaattctc ctgaggctaa acacagtttg tttttcttgt
2941 aatcactttt catgttaaaa taatcagcat tcaaattgta tgctttctga atatagactt
3001 tctgggaaaa ggtttactgc tcgtaaggaa acattttatg tattaaaata aactgttcct
3061 tgataaaaaa aaaaaaaaaa aa
//