LOCUS BC012043 2380 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 12, mRNA (cDNA
clone MGC:10252 IMAGE:3622879), complete cds.
ACCESSION BC012043
VERSION BC012043.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2380)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2380)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: a Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7705854.
FEATURES Location/Qualifiers
source 1..2380
/db_xref="H-InvDB:HIT000035615"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10252 IMAGE:3622879"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2380
/gene="HSD17B12"
/gene_synonym="KAR"
/db_xref="GeneID:51144"
/db_xref="HGNC:HGNC:18646"
/db_xref="MIM:609574"
CDS 59..997
/gene="HSD17B12"
/gene_synonym="KAR"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 12"
/protein_id="AAH12043.1"
/db_xref="GeneID:51144"
/db_xref="HGNC:HGNC:18646"
/db_xref="MIM:609574"
/translation="MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAG
VGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVET
RTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMINI
NILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHE
EYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHA
LMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN"
BASE COUNT 772 a 433 c 466 g 709 t
ORIGIN
1 ctggattcat tcactcgctc ttttcattca cgaaggtagt gaggcctagt ggaaagccat
61 ggagagcgct ctccccgccg ccggcttcct gtactgggtc ggcgcgggca ccgtggccta
121 cctagccctg cgtatttcgt actcgctctt cacggccctc cgggtctggg gagtggggaa
181 tgaggcgggg gtcggcccgg ggctcggaga atgggcagtt gtcacaggta gtactgatgg
241 aattggaaaa tcatatgcag aagagttagc aaagcatgga atgaaggttg tccttatcag
301 cagatcaaag gataaacttg accaggtttc cagtgaaata aaagaaaaat tcaaagtgga
361 gacaagaacc attgctgttg actttgcatc agaagatatt tatgataaaa ttaaaacagg
421 cttggctggt cttgaaatcg gcatcttagt gaacaacgtg ggaatgtcgt atgagtatcc
481 tgaatacttt ttggatgttc ctgacttgga caatgtgatc aagaaaatga taaatattaa
541 tattctttct gtttgtaaga tgacacaatt ggtactgcct ggcatggtgg aaagatccaa
601 aggggctatt ctgaacattt catctggcag tggcatgctc cctgtcccac tcttgaccat
661 ctattctgca accaagactt ttgtagattt cttctctcag tgcctccatg aggagtatag
721 gagcaagggc gtctttgtgc agagtgtcct gccatacttc gtagctacaa aactggctaa
781 aatccggaag ccaactttgg ataagccctc tccggagacg tttgtgaagt ctgcaattaa
841 aacagtcggc ctgcaatccc gaaccaatgg atacctgatc catgctctta tgggctcgat
901 aatctcaaac ctgccttctt ggatttattt gaaaatagtc atgaatatga acaagtctac
961 acgggctcac tatctgaaga aaaccaagaa gaactaagca ttgataactg cattgtaact
1021 tggccagatg ctccagcata tgcacgttca ctgcaaagca ccctactggt tttgaaaatc
1081 tgaccttgtc atttcaatag ttattaacat gactaaatat tatcttaatt aagaggaaaa
1141 tagaagttgc ttttaggggt ttctgacata tattctggat actatccgag gtaattttga
1201 agtttaatat aaatgctcat atcaaatgaa tatagaacta atattgtcgg gaacacctaa
1261 tagaaaggaa tactattata gcaaatcaca gaatgataga ctcaagcata aaacttggca
1321 gttttatctg cttcaaaatg ccattgatca ttattcctgt attttctctg aaactgatta
1381 taaaaaccaa tgtccagcta ctcttttgtt tttgacactt gaagaaatgg agatcgattt
1441 gatttgttta taagcagaca cactgcaatt tacaaagatc tctttacggt tttataaaat
1501 tatcttccag tttgtacatt tatatggaat tgttctttat caagggtagc taatgacatg
1561 aaaataattg tgaaatatgg aattatttct gacacatgaa gcccactaaa ctatgctttc
1621 ttataatgca tatttcttct cagtttaaat gtatgtaaat atcgaagcta tatggtatga
1681 tttataaaga taaatgggcc aaagtgtaca ttgagactgg cagccatcta tggtaccact
1741 gaaaccctga cccagaaaag tggcttgctt ggacacccag ctgcctttgt ttctgcatta
1801 aaccaatatt gatcacacat atgacacagg ctagtcctat aaaagtaatg acttcataga
1861 aatggcatta taatttttaa gttgatactc tacaggtagc tattgatata attagtttta
1921 ataaaacatg ctgcaaccat ggtatacaac aaaaatacat ttctttggtg attgaaatta
1981 aggccgtatt tacaatgact taatataaga ctgactttta tcctgcttca taacttgtat
2041 ggagaactca ccaagaaaga attcaatact gtgaaatatg cagcaagaag attggtcttt
2101 acctaggctg tgtttcctaa gctctgagtt ttcagcacca gtagatttgt attaaaagaa
2161 aaaaaaatgg ggccttagct tctggctttt aattttgcca gctaaggaca taaaacaaaa
2221 ataaacaaac aaaaacaaat agccatctgc tatcagcatc attatgtaaa agaaaatata
2281 ttttagcccc taaaattagg aagaatgtaa tctcagaata aaggttgtca tttaagttga
2341 ataaatatat agctttatga aaaaaaaaaa aaaaaaaaaa
//