LOCUS BC011935 1213 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens catechol-O-methyltransferase, mRNA (cDNA clone
MGC:20006 IMAGE:3503220), complete cds.
ACCESSION BC011935
VERSION BC011935.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1213)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1213)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011935.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: b Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6466449.
FEATURES Location/Qualifiers
source 1..1213
/db_xref="H-InvDB:HIT000035552"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20006 IMAGE:3503220"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1213
/gene="COMT"
/db_xref="GeneID:1312"
/db_xref="HGNC:HGNC:2228"
/db_xref="MIM:116790"
CDS 93..908
/gene="COMT"
/codon_start=1
/product="catechol-O-methyltransferase"
/protein_id="AAH11935.1"
/db_xref="GeneID:1312"
/db_xref="HGNC:HGNC:2228"
/db_xref="MIM:116790"
/translation="MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQ
PIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDA
VIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKD
KVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLA
DNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGP"
BASE COUNT 271 a 345 c 348 g 249 t
ORIGIN
1 gaaataacat ctgctttgct gccgagctca gaggagaccc cagacccctc ccgcagccag
61 agggctggag cctgctcaga ggtgctttga agatgccgga ggccccgcct ctgctgttgg
121 cagctgtgtt gctgggcctg gtgctgctgg tggtgctgct gctgcttctg aggcactggg
181 gctggggcct gtgccttatc ggctggaacg agttcatcct gcagcccatc cacaacctgc
241 tcatgggtga caccaaggag cagcgcatcc tgaaccacgt gctgcagcat gcggagcccg
301 ggaacgcaca gagcgtgctg gaggccattg acacctactg cgagcagaag gagtgggcca
361 tgaacgtggg cgacaagaaa ggcaagatcg tggacgccgt gattcaggag caccagccct
421 ccgtgctgct ggagctgggg gcctactgtg gctactcagc tgtgcgcatg gcccgcctgc
481 tgtcaccagg ggcgaggctg atcaccatcg agatcaaccc cgactgtgcc gccatcaccc
541 agcggatggt ggatttcgct ggcgtgaagg acaaggtcac ccttgtggtt ggagcgtccc
601 aggacatcat cccccagctg aagaagaagt atgatgtgga cacactggac atggtcttcc
661 tcgaccactg gaaggaccgg tacctgccgg acacgcttct cttggaggaa tgtggcctgc
721 tgcggaaggg gacagtgcta ctggctgaca acgtgatctg cccaggtgcg ccagacttcc
781 tagcacacgt gcgcgggagc agctgctttg agtgcacaca ctaccaatcg ttcctggaat
841 acagggaggt ggtggacggc ctggagaagg ccatctacaa gggcccaggc agcgaagcag
901 ggccctgact gccccccccg gcccccctct cgggctctct cacccagcct ggtactgaag
961 gtgccagacg tgctcctgct gaccttctgc ggctccgggc tgtgtcctaa atgcaaagca
1021 cacctcggcc gaggcctgcg ccctgacatg ctaacctctc tgaactgcaa cactggattg
1081 ttctttttta agactcaatc atgacttctt tactaacact ggctagctat attatcttat
1141 atactaatat catgttttaa aaatataaaa tagaaattaa gaatctaaat atttagataa
1201 aaaaaaaaaa aaa
//