LOCUS BC011913 2155 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 7,
mRNA (cDNA clone MGC:20089 IMAGE:4298811), complete cds.
ACCESSION BC011913
VERSION BC011913.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2155)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2155)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011913.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: k Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34335274.
FEATURES Location/Qualifiers
source 1..2155
/db_xref="H-InvDB:HIT000035539"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20089 IMAGE:4298811"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2155
/gene="P2RX7"
/gene_synonym="MGC20089"
/gene_synonym="P2X7"
/db_xref="GeneID:5027"
/db_xref="HGNC:HGNC:8537"
/db_xref="MIM:602566"
CDS 70..1857
/gene="P2RX7"
/gene_synonym="MGC20089"
/gene_synonym="P2X7"
/codon_start=1
/product="purinergic receptor P2X, ligand-gated ion
channel, 7"
/protein_id="AAH11913.1"
/db_xref="GeneID:5027"
/db_xref="HGNC:HGNC:8537"
/db_xref="MIM:602566"
/translation="MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFA
LVSDKLYQRKEPVISSVHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSF
FVMTNFLKTEGQEQRLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVHEGNQK
TCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTF
HKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCHPKYSFR
RLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLV
VYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIV
EPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDTP
PIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACIT
TSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMADF
AILPSCCRWRIRKEFPKSEGQYSGFKSPY"
BASE COUNT 542 a 580 c 567 g 466 t
ORIGIN
1 gcttgctgtg gccctgtcag gaagagtaga gctctggtcc agctccgcgc agggagggag
61 gctgtcacca tgccggcctg ctgcagctgc agtgatgttt tccagtatga gacgaacaaa
121 gtcactcgga tccagagcat gaattatggc accattaagt ggttcttcca cgtgatcatc
181 ttttcctacg tttgctttgc tctggtgagt gacaagctgt accagcggaa agagcctgtc
241 atcagttctg tgcacaccaa ggtgaagggg atagcagagg tgaaagagga gatcgtggag
301 aatggagtga agaagttggt gcacagtgtc tttgacaccg cagactacac cttccctttg
361 caggggaact ctttcttcgt gatgacaaac tttctcaaaa cagaaggcca agagcagcgg
421 ttgtgtcccg agtatcccac ccgcaggacg ctctgttcct ctgaccgagg ttgtaaaaag
481 ggatggatgg acccgcagag caaaggaatt cagaccggaa ggtgtgtagt gcatgaaggg
541 aaccagaaga cctgtgaagt ctctgcctgg tgccccatcg aggcagtgga agaggccccc
601 cggcctgctc tcttgaacag tgccgaaaac ttcactgtgc tcatcaagaa caatatcgac
661 ttccccggcc acaactacac cacgagaaac atcctgccag gtttaaacat cacttgtacc
721 ttccacaaga ctcagaatcc acagtgtccc attttccgac taggagacat cttccgagaa
781 acaggcgata atttttcaga tgtggcaatt cagggcggaa taatgggcat tgagatctac
841 tgggactgca acctagaccg ttggttccat cactgccatc ccaaatacag tttccgtcgc
901 cttgacgaca agaccaccaa cgtgtccttg taccctggct acaacttcag atacgccaag
961 tactacaagg aaaacaatgt tgagaaacgg actctgataa aagtcttcgg gatccgtttt
1021 gacatcctgg tttttggcac cggaggaaaa tttgacatta tccagctggt tgtgtacatc
1081 ggctcaaccc tctcctactt cggtctggcc gctgtgttca tcgacttcct catcgacact
1141 tactccagta actgctgtcg ctcccatatt tatccctggt gcaagtgctg tcagccctgt
1201 gtggtcaacg aatactacta caggaagaag tgcgagtcca ttgtggagcc aaagccgaca
1261 ttaaagtatg tgtcctttgt ggatgaatcc cacattagga tggtgaacca gcagctacta
1321 gggagaagtc tgcaagatgt caagggccaa gaagtcccaa gacctgcgat ggacttcaca
1381 gatttgtcca ggctgcccct ggccctccat gacacacccc cgattcctgg acaaccagag
1441 gagatacagc tgcttagaaa ggaggcgact cctagatcca gggatagccc cgtctggtgc
1501 cagtgtggaa gctgcctccc atctcaactc cctgagagcc acaggtgcct ggaggagctg
1561 tgctgccgga aaaagccggg ggcctgcatc accacctcag agctgttcag gaagctggtc
1621 ctgtccagac acgtcctgca gttcctcctg ctctaccagg agcccttgct ggcgctggat
1681 gtggattcca ccaacagccg gctgcggcac tgtgcctaca ggtgctacgc cacctggcgc
1741 ttcggctccc aggacatggc tgactttgcc atcctgccca gctgctgccg ctggaggatc
1801 cggaaagagt ttccgaagag tgaagggcag tacagtggct tcaagagtcc ttactgaagc
1861 caggcaccgt ggctcacgtc tgtaatccca gcgctttggg aggccgaggc aggcagatca
1921 cctgaggtcg ggagttggag acccgcctgg ctaacaaggc gaaatcctgt ctgtactaaa
1981 aatacaaaaa tcagccagac atggtggcat gcacctgcaa tcccagctac tcgggaggct
2041 gaggcacaag aatcacttga acccgggagg cagaggttgt agtgagccca gattgtgcca
2101 ctgctctcca gcctgggagg cacagcaaac tgtcccaaaa aaaaaaaaaa aaaaa
//