LOCUS BC011911 2113 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serine hydroxymethyltransferase 2 (mitochondrial),
mRNA (cDNA clone MGC:20325 IMAGE:4139001), complete cds.
ACCESSION BC011911
VERSION BC011911.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2113)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2113)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC011911.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: k Column: 18.
FEATURES Location/Qualifiers
source 1..2113
/db_xref="H-InvDB:HIT000035537"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20325 IMAGE:4139001"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2113
/gene="SHMT2"
/gene_synonym="GLYA"
/db_xref="GeneID:6472"
/db_xref="HGNC:HGNC:10852"
/db_xref="MIM:138450"
CDS 11..1525
/gene="SHMT2"
/gene_synonym="GLYA"
/codon_start=1
/product="serine hydroxymethyltransferase 2
(mitochondrial)"
/protein_id="AAH11911.1"
/db_xref="GeneID:6472"
/db_xref="HGNC:HGNC:10852"
/db_xref="MIM:138450"
/translation="MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWT
GQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPG
KRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDR
IMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRP
RLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTT
TTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAA
VAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLD
GARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE
GVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH"
BASE COUNT 470 a 589 c 585 g 469 t
ORIGIN
1 ccgagttgcg atgctgtact tctctttgtt ttgggcggct cggcctctgc agagatgtgg
61 gcagctggtc aggatggcca ttcgggctca gcacagcaac gcagcccaga ctcagactgg
121 ggaagcaaac aggggctgga caggccagga gagcctgtcg gacagtgatc ctgagatgtg
181 ggagttgctg cagagggaga aggacaggca gtgtcgtggc ctggagctca ttgcctcaga
241 gaacttctgc agccgagctg cgctggaggc cctggggtcc tgtctgaaca acaagtactc
301 ggagggttat cctggcaaga gatactatgg gggagcagag gtggtggatg aaattgagct
361 gctgtgccag cgccgggcct tggaagcctt tgacctggat cctgcacagt ggggagtcaa
421 tgtccagccc tactccgggt ccccagccaa cctggccgtc tacacagccc ttctgcaacc
481 tcacgaccgg atcatggggc tggacctgcc cgatgggggc catctcaccc acggctacat
541 gtctgacgtc aagcggatat cagccacgtc catcttcttc gagtctatgc cctataagct
601 caaccccaaa actggcctca ttgactacaa ccagctggca ctgactgctc gacttttccg
661 gccacggctc atcatagctg gcaccagcgc ctatgctcgc ctcattgact acgcccgcat
721 gagagaggtg tgtgatgaag tcaaagcaca cctgctggca gacatggccc acatcagtgg
781 cctggtggct gccaaggtga ttccctcgcc tttcaagcac gcggacatcg tcaccaccac
841 tactcacaag actcttcgag gggccaggtc agggctcatc ttctaccgga aaggggtgaa
901 ggctgtggac cccaagactg gccgggagat cccttacaca tttgaggacc gaatcaactt
961 tgccgtgttc ccatccctgc aggggggccc ccacaatcat gccattgctg cagtagctgt
1021 ggccctaaag caggcctgca cccccatgtt ccgggagtac tccctgcagg ttctgaagaa
1081 tgctcgggcc atggcagatg ccctgctaga gcgaggctac tcactggtat caggtggtac
1141 tgacaaccac ctggtgctgg tggacctgcg gcccaagggc ctggatggag ctcgggctga
1201 gcgggtgcta gagcttgtat ccatcactgc caacaagaac acctgtcctg gagaccgaag
1261 tgccatcaca ccgggcggcc tgcggcttgg ggccccagcc ttaacttctc gacagttccg
1321 tgaggatgac ttccggagag ttgtggactt tatagatgaa ggggtcaaca ttggcttaga
1381 ggtgaagagc aagactgcca agctccagga tttcaaatcc ttcctgctta aggactcaga
1441 aacaagtcag cgtctggcca acctcaggca acgggtggag cagtttgcca gggccttccc
1501 catgcctggt tttgatgagc attgaaggca cctgggaaat gaggcccaca gactcaaagt
1561 tactctcctt ccccctacct gggccagtga aatagaaagc ctttctattt tttggtgcgg
1621 gagggaagac ctctcactta gggcaagagc caggtatagt ctcccttccc agaatttgta
1681 actgagaaga tcttttcttt ttcctttttt tggtaacaag acttagaagg agggcccagg
1741 cactttctgt ttgaacccct gtcatgatca cagtgtcaga gacgcgtcct ctttcttggg
1801 gaagttgagg agtgcccttc agagccagta gcaggcaggg gtgggtaggc accctccttc
1861 ctgtttttat ctaataaaat gctaacctgc cctgagtttc cattactgtg ggtggggttc
1921 ccctgggcca aacagtgatt tgtctccctc aatgtgtaca ccgctccgct cccaccaccg
1981 ctaccacaag gacccccggg gctgcagcct cctctttctg tctctgatca gagccgacac
2041 cagacgtgat tagcaggcgc agcaaattca atttgttaaa tgaaattgta ttttgaaaaa
2101 aaaaaaaaaa aaa
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