LOCUS BC011865 3178 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens junction plakoglobin, mRNA (cDNA clone MGC:20213
IMAGE:4542042), complete cds.
ACCESSION BC011865
VERSION BC011865.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3178)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3178)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011865.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: o Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3178
/db_xref="H-InvDB:HIT000035502"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20213 IMAGE:4542042"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3178
/gene="JUP"
/gene_synonym="ARVD12"
/gene_synonym="DP3"
/gene_synonym="DPIII"
/gene_synonym="PDGB"
/gene_synonym="PKGB"
/db_xref="GeneID:3728"
/db_xref="HGNC:HGNC:6207"
/db_xref="MIM:173325"
CDS 278..2515
/gene="JUP"
/gene_synonym="ARVD12"
/gene_synonym="DP3"
/gene_synonym="DPIII"
/gene_synonym="PDGB"
/gene_synonym="PKGB"
/codon_start=1
/product="JUP protein"
/protein_id="AAH11865.1"
/db_xref="GeneID:3728"
/db_xref="HGNC:HGNC:6207"
/db_xref="MIM:173325"
/translation="MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIME
EDEACGRQYTLKKTTTYTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLL
ATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVT
KAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREG
LLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPL
LNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRV
LKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESV
LKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDD
ITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNL
ALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGA
LHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAE
GASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEA
AQSMIPINEPYGDDLDATYRPMYSSDVPLDPLEMHMDMDGDYPIDTYSDGLRPPYPTA
DHMLA"
BASE COUNT 671 a 1010 c 896 g 601 t
ORIGIN
1 ggcagaagcg catgaggctg tgggacttgc cttccatttg atttctgaat tgtgaaggtg
61 catgctttct ggaggcctgc acagaccttt cccacccgct ttcctgaaag aatttgacag
121 ggaaagtgag accgcaggaa ggctttttgg gggaaggttt cttcaatgct agactctctc
181 aggcagagct gcatcgggcc ccctgccttc cctgctccca atttcctgag accgcccgcc
241 cccacccaga attggggatc ttgatcaggt agccacgatg gaggtgatga acctgatgga
301 gcagcctatc aaggtgactg agtggcagca gacatacacc tacgactcgg gtatccactc
361 gggcgccaac acctgcgtgc cctccgtcag cagcaagggc atcatggagg aggatgaggc
421 ctgcgggcgc cagtacacgc tcaagaaaac caccacttac acccaggggg tgccccccag
481 ccaaggtgac ctggagtacc agatgtccac aacagccagg gccaaacggg tgcgggaggc
541 catgtgccct ggtgtgtcag gcgaggacag ctcgcttctg ctggccaccc aggtggaggg
601 gcaggccacc aacctgcagc gactggccga gccgtcccag ctgctcaagt cggccattgt
661 gcatctcatc aactaccagg atgatgccga gctggccact cgcgccctgc ccgagctcac
721 caaactgctc aacgacgagg acccggtggt ggtgaccaag gcggccatga ttgtgaacca
781 gctgtcgaag aaggaggcgt cgcggcgggc cctgatgggc tcgccccagc tggtggccgc
841 tgtcgtgcgt accatgcaga ataccagcga cctggacaca gcccgctgca ccaccagcat
901 cctgcacaac ctctcccacc accgggaggg gctgctcgcc atcttcaagt cgggtggcat
961 ccctgctctg gtccgcatgc tcagctcccc tgtggagtcg gtcctgttct atgccatcac
1021 cacgctgcac aacctgctcc tgtaccagga gggcgccaag atggccgtgc gcctggccga
1081 cgggctgcaa aagatggtgc ccctgctcaa caagaacaac cccaagttcc tggccatcac
1141 caccgactgc ctgcagctcc tggcctacgg caaccaggag agcaagctga tcatcctggc
1201 caatggtggg ccccaggccc tcgtgcagat catgcgtaac tacagttatg aaaagctgct
1261 ctggaccacc agtcgtgtgc tcaaggtgct atccgtgtgt cccagcaata agcctgccat
1321 tgtggaggct ggtgggatgc aggccctggg caagcacctg accagcaaca gcccccgcct
1381 ggtgcagaac tgcctgtgga ccctgcgcaa cctctcagat gtggccacca agcaggaggg
1441 cctggagagt gtgctgaaga ttctggtgaa tcagctgagt gtggatgacg tcaacgtcct
1501 cacctgtgcc acgggcacac tctccaacct gacatgcaac aacagcaaga acaagacgct
1561 ggtgacacag aacagcggtg tggaggctct catccatgcc atcctgcgtg ctggtgacaa
1621 ggacgacatc acggagcctg ccgtctgcgc tctgcgccac ctcactagcc gccaccctga
1681 ggccgagatg gcccagaact ctgtgcgtct caactatggc atcccagcca tcgtgaagct
1741 gctcaaccag cccaaccagt ggccactggt caaggcaacc atcggcttga tcaggaatct
1801 ggccctgtgc ccagccaacc atgccccgct gcaggaggca gcggtcatcc cccgcctcgt
1861 ccaactgctg gtgaaggccc accaggatgc ccagcgccac gtagctgcag gcacacagca
1921 gccctacacg gatggtgtga ggatggagga gattgtggag ggctgcaccg gagcactgca
1981 catcctcgcc cgggacccca tgaaccgcat ggagatcttc cggctcaaca ccattcccct
2041 gtttgtgcag ctcctgtact cgtcggtgga gaacatccag cgcgtggctg ccggggtgct
2101 gtgtgagctg gcccaggaca aggaggcggc cgacgccatt gatgcagagg gggcctcggc
2161 cccactcatg gagttgctgc actcccgcaa cgagggcact gccacctacg ctgctgccgt
2221 cctgttccgc atctccgagg acaagaaccc agactaccgg aagcgcgtgt ccgtggagct
2281 caccaactcc ctcttcaagc atgacccggc tgcctgggag gctgcccaga gcatgattcc
2341 catcaatgag ccctatggag atgacttgga tgccacctac cgccccatgt actccagcga
2401 tgtgcccctt gacccgctgg agatgcacat ggacatggat ggagactacc ccatcgacac
2461 ctacagcgac ggcctcaggc ccccgtaccc cactgcagac cacatgctgg cctaggcggc
2521 ctggccccag tgcggttcct catctgagag gctctccgtg caggcgatgg ggcaagacag
2581 aaaagtgcct gagctgggga agccggggtg taacttcctg ctgcaccctg cgcctccaga
2641 ggtcctccgt agggtctttc ttgggatagt gttctgctcc tgcttttctg tcctgggcat
2701 gggtccaggg cctgacaccc cctccagggc ccaggttcga gacccaaacc cccaaaatcc
2761 aaaacttctc ttgaaaagtt cagggaccgt ccaggggaga tggggaggag atatggagtg
2821 agtcacctgc tccagaagat gccagcttct ctctccaggg tgcttagttg gctttgccca
2881 cccctcactc cccagggagc tctggggaca gcttcctcac acccctgtcc cacccacaca
2941 gctgccctag ctgaccccga gaagtgctct tggctgaccc ctctggtgtg tggtgagggg
3001 ctttctcttc cccttcctgt ttcagacccc cccatttccc gcacatggtg tggggggctg
3061 ggggaggtcc aagcagagtg ttttattatt atcgctttat gtttttggtt attggttttt
3121 ttgtatagac caaagcaaag aaaataaaaa taacaaaaaa aaaaaaaaaa aaaaaaaa
//