LOCUS BC011847 3175 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fibroblast growth factor receptor 4, mRNA (cDNA clone
MGC:20292 IMAGE:4121396), complete cds.
ACCESSION BC011847
VERSION BC011847.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3175)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3175)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011847.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: i Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47524176.
FEATURES Location/Qualifiers
source 1..3175
/db_xref="H-InvDB:HIT000035489"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20292 IMAGE:4121396"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3175
/gene="FGFR4"
/gene_synonym="CD334"
/gene_synonym="JTK2"
/gene_synonym="MGC20292"
/gene_synonym="TKF"
/db_xref="GeneID:2264"
/db_xref="HGNC:HGNC:3691"
/db_xref="MIM:134935"
CDS 246..2654
/gene="FGFR4"
/gene_synonym="CD334"
/gene_synonym="JTK2"
/gene_synonym="MGC20292"
/gene_synonym="TKF"
/codon_start=1
/product="fibroblast growth factor receptor 4"
/protein_id="AAH11847.1"
/db_xref="GeneID:2264"
/db_xref="HGNC:HGNC:3691"
/db_xref="MIM:134935"
/translation="MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQE
LTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCL
ARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLH
AVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD
RGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD
AQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCL
AGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRG
QALHGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLV
SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDN
ASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARR
PPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDN
VMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEI
FTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLV
EALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGS
GVQT"
BASE COUNT 612 a 999 c 974 g 590 t
ORIGIN
1 cgctcgcggc cacgccgccg tcgcgggtac attcctcgct cccggccgag gagcgctcgg
61 gctgtctgcg gaccctgccg cgtgcagggg tcgcggccgg ctggagctgg gagtgaggcg
121 gcggaggagc caggtgagga ggagccaggt gagcaggacc ctgtgctggg cgcggagtca
181 cgcaggctcg aggaaggcag ttggtgggaa gtccagcttg ggtccctgag agctgtgaga
241 aggagatgcg gctgctgctg gccctgttgg gggtcctgct gagtgtgcct gggcctccag
301 tcttgtccct ggaggcctct gaggaagtgg agcttgagcc ctgcctggct cccagcctgg
361 agcagcaaga gcaggagctg acagtagccc ttgggcagcc tgtgcgtctg tgctgtgggc
421 gggctgagcg tggtggccac tggtacaagg agggcagtcg cctggcacct gctggccgtg
481 tacggggctg gaggggccgc ctagagattg ccagcttcct acctgaggat gctggccgct
541 acctctgcct ggcacgaggc tccatgatcg tcctgcagaa tctcaccttg attacaggtg
601 actccttgac ctccagcaac gatgatgagg accccaagtc ccatagggac ccctcgaata
661 ggcacagtta cccccagcaa gcaccctact ggacacaccc ccagcgcatg gagaagaaac
721 tgcatgcagt acctgcgggg aacaccgtca agttccgctg tccagctgca ggcaacccca
781 cgcccaccat ccgctggctt aaggatggac aggcctttca tggggagaac cgcattggag
841 gcattcggct gcgccatcag cactggagtc tcgtgatgga gagcgtggtg ccctcggacc
901 gcggcacata cacctgcctg gtagagaacg ctgtgggcag catccgctat aactacctgc
961 tagatgtgct ggagcggtcc ccgcaccggc ccatcctgca ggccgggctc ccggccaaca
1021 ccacagccgt ggtgggcagc gacgtggagc tgctgtgcaa ggtgtacagc gatgcccagc
1081 cccacatcca gtggctgaag cacatcgtca tcaacggcag cagcttcgga gccgacggtt
1141 tcccctatgt gcaagtccta aagactgcag acatcaatag ctcagaggtg gaggtcctgt
1201 acctgcggaa cgtgtcagcc gaggacgcag gcgagtacac ctgcctcgca ggcaattcca
1261 tcggcctctc ctaccagtct gcctggctca cggtgctgcc agaggaggac cccacatgga
1321 ccgcagcagc gcccgaggcc aggtatacgg acatcatcct gtacgcgtcg ggctccctgg
1381 ccttggctgt gctcctgctg ctggccgggc tgtatcgagg gcaggcgctc cacggccggc
1441 acccccgccc gcccgccact gtgcagaagc tctcccgctt ccctctggcc cgacagttct
1501 ccctggagtc aggctcttcc ggcaagtcaa gctcatccct ggtacgaggc gtgcgtctct
1561 cctccagcgg ccccgccttg ctcgccggcc tcgtgagtct agatctacct ctcgacccac
1621 tatgggagtt cccccgggac aggctggtgc ttgggaagcc cctaggcgag ggctgctttg
1681 gccaggtagt acgtgcagag gcctttggca tggaccctgc ccggcctgac caagccagca
1741 ctgtggccgt caagatgctc aaagacaacg cctctgacaa ggacctggcc gacctggtct
1801 cggagatgga ggtgatgaag ctgatcggcc gacacaagaa catcatcaac ctgcttggtg
1861 tctgcaccca ggaagggccc ctgtacgtga tcgtggagtg cgccgccaag ggaaacctgc
1921 gggagttcct gcgggcccgg cgccccccag gccccgacct cagccccgac ggtcctcgga
1981 gcagtgaggg gccgctctcc ttcccagtcc tggtctcctg cgcctaccag gtggcccgag
2041 gcatgcagta tctggagtcc cggaagtgta tccaccggga cctggctgcc cgcaatgtgc
2101 tggtgactga ggacaatgtg atgaagattg ctgactttgg gctggcccgc ggcgtccacc
2161 acattgacta ctataagaaa accagcaacg gccgcctgcc tgtgaagtgg atggcgcccg
2221 aggccttgtt tgaccgggtg tacacacacc agagtgacgt gtggtctttt gggatcctgc
2281 tatgggagat cttcaccctc gggggctccc cgtatcctgg catcccggtg gaggagctgt
2341 tctcgctgct gcgggaggga catcggatgg accgaccccc acactgcccc ccagagctgt
2401 acgggctgat gcgtgagtgc tggcacgcag cgccctccca gaggcctacc ttcaagcagc
2461 tggtggaggc gctggacaag gtcctgctgg ccgtctctga ggagtacctc gacctccgcc
2521 tgaccttcgg accctattcc ccctctggtg gggacgccag cagcacctgc tcctccagcg
2581 attctgtctt cagccacgac cccctgccat tgggatccag ctccttcccc ttcgggtctg
2641 gggtgcagac atgagcaagg ctcaaggctg tgcaggcaca taggctggtg gccttgggcc
2701 ttggggctca gccacagcct gacacagtgc tcgaccttga tagcatgggg cccctggccc
2761 agagttgctg tgccgtgtcc aagggccgtg cccttgccct tggagctgcc gtgcctgtgt
2821 cctgatggcc caaatgtcag ggttctgctc ggcttcttgg accttggcgc ttagtcccca
2881 tcccgggttt ggctgagcct ggctggagag ctgctatgct aaacctcctg cctcccaata
2941 ccagcaggag gttctgggcc tctgaacccc ctttccccac acctccccct gctgctgctg
3001 ccccagcgtc ttgacgggag cattggcccc tgagcccaga gaagctggaa gcctgccgaa
3061 aacaggagca aatggcgttt tataaattat ttttttgaaa taaaaaaaaa aaaaaaaaaa
3121 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//