LOCUS BC011737 1641 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens uncoupling protein 2 (mitochondrial, proton carrier),
mRNA (cDNA clone MGC:19567 IMAGE:4335185), complete cds.
ACCESSION BC011737
VERSION BC011737.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1641)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1641)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011737.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 27 Row: p Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13259540.
FEATURES Location/Qualifiers
source 1..1641
/db_xref="H-InvDB:HIT000035413"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19567 IMAGE:4335185"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1641
/gene="UCP2"
/gene_synonym="SLC25A8"
/gene_synonym="UCPH"
/db_xref="GeneID:7351"
/db_xref="HGNC:HGNC:12518"
/db_xref="MIM:601693"
CDS 344..1273
/gene="UCP2"
/gene_synonym="SLC25A8"
/gene_synonym="UCPH"
/codon_start=1
/product="uncoupling protein 2 (mitochondrial, proton
carrier)"
/protein_id="AAH11737.1"
/db_xref="GeneID:7351"
/db_xref="HGNC:HGNC:12518"
/db_xref="MIM:601693"
/translation="MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQ
GESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDS
VKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTV
NAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHF
TSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPS
FLRLGSWNVVMFVTYEQLKRALMAACTSREAPF"
BASE COUNT 336 a 522 c 392 g 391 t
ORIGIN
1 tgtccacgct cgcccggctc gtccgacgcg ccctccgcca gccgacagac acagccgcac
61 gcactgccgt gttctccctg cggctcggac acatagtatg accattaggt gtttcgtctc
121 ccacccattt tctatggaaa accaagggga tcgggccatg atagccactg gcagctttga
181 agaacgggac acctttagag aagcttgatc ttggaggcct caccgtgaga ccttacaaag
241 ccggattccg gcagagttcc tctatctcgt cttgttgctg attaaaggtg cccctgtctc
301 cagtttttct ccatctcctg ggacgtagca ggaaatcagc atcatggttg ggttcaaggc
361 cacagatgtg ccccctactg ccactgtgaa gtttcttggg gctggcacag ctgcctgcat
421 cgcagatctc atcacctttc ctctggatac tgctaaagtc cggttacaga tccaaggaga
481 aagtcagggg ccagtgcgcg ctacagccag cgcccagtac cgcggtgtga tgggcaccat
541 tctgaccatg gtgcgtactg agggcccccg aagcctctac aatgggctgg ttgccggcct
601 gcagcgccaa atgagctttg cctctgtccg catcggcctg tatgattctg tcaaacagtt
661 ctacaccaag ggctctgagc atgccagcat tgggagccgc ctcctagcag gcagcaccac
721 aggtgccctg gctgtggctg tggcccagcc cacggatgtg gtaaaggtcc gattccaagc
781 tcaggcccgg gctggaggtg gtcggagata ccaaagcacc gtcaatgcct acaagaccat
841 tgcccgagag gaagggttcc ggggcctctg gaaagggacc tctcccaatg ttgctcgtaa
901 tgccattgtc aactgtgctg agctggtgac ctatgacctc atcaaggatg ccctcctgaa
961 agccaacctc atgacagatg acctcccttg ccacttcact tctgcctttg gggcaggctt
1021 ctgcaccact gtcatcgcct cccctgtaga cgtggtcaag acgagataca tgaactctgc
1081 cctgggccag tacagtagcg ctggccactg tgcccttacc atgctccaga aggaggggcc
1141 ccgagccttc tacaaagggt tcatgccctc ctttctccgc ttgggttcct ggaacgtggt
1201 gatgttcgtc acctatgagc agctgaaacg agccctcatg gctgcctgca cttcccgaga
1261 ggctcccttc tgagcctctc ctgctgctga cctgatcacc tctggctttg tctctagccg
1321 ggccatgctt tccttttctt ccttctttct cttccctcct tcccttctct ccttccctct
1381 ttccccacct cttccttccg ctcctttacc taccaccttc cctctttcta cattctcatc
1441 tactcattgt ctcagtgctg gtggagttga catttgacag tgtgggaggc ctcgtaccag
1501 ccaggatccc aagcgtcccg tcccttggaa agttcagcca gaatcttcgt cctgcccccg
1561 acagcccagc ctagcccact tgtcatccat aaagcaagct caaccttgaa aaaaaaaaaa
1621 aaaaaaaaaa aaaaaaaaaa a
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