LOCUS BC011654 2268 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cleavage and polyadenylation specific factor 3, 73kDa,
mRNA (cDNA clone MGC:12899 IMAGE:4304135), complete cds.
ACCESSION BC011654
VERSION BC011654.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2268)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2268)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011654.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: o Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..2268
/db_xref="H-InvDB:HIT000035353"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12899 IMAGE:4304135"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2268
/gene="CPSF3"
/gene_synonym="CPSF"
/gene_synonym="CPSF-73"
/gene_synonym="CPSF73"
/db_xref="GeneID:51692"
/db_xref="HGNC:HGNC:2326"
/db_xref="MIM:606029"
CDS 111..2165
/gene="CPSF3"
/gene_synonym="CPSF"
/gene_synonym="CPSF-73"
/gene_synonym="CPSF73"
/codon_start=1
/product="cleavage and polyadenylation specific factor 3,
73kDa"
/protein_id="AAH11654.1"
/db_xref="GeneID:51692"
/db_xref="HGNC:HGNC:2326"
/db_xref="MIM:606029"
/translation="MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIH
PGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAI
YRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHGVKEVAGIKFWCYHAGHVL
GAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREER
EARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAK
KCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQS
GLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYIS
FSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRN
TEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAM
STVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLE
WLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGE
DCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTP
VH"
BASE COUNT 714 a 446 c 504 g 604 t
ORIGIN
1 ctcttggtga atggggttct tcctttttta tttaccggtg gctgtgcttc caatttagga
61 agaccccggc gacctgttcc tcacccccgc ttcgccctca cactttcggg atgtctgcga
121 ttcctgctga ggagagcgac cagctgctga tccgacccct tggagctggg caagaagtag
181 gaagatcatg tattattctc gagttcaaag gaagaaaaat aatgctcgac tgtgggatcc
241 accctggcct agaaggaatg gatgctcttc cttatattga tttaattgac ccagctgaga
301 ttgatctcct attaattagt catttccatt tggatcactg tggagctctg ccctggtttc
361 tacagaagac aagtttcaaa ggaagaacat ttatgactca tgccacaaaa gctatttata
421 gatggcttct ttctgattat gtcaaagtta gtaacatatc agcagacgac atgctgtata
481 ccgagacaga tttggaagaa agcatggaca aaattgaaac tatcaacttt catggagtta
541 aggaagttgc gggaatcaag ttttggtgtt accatgcagg tcacgtccta ggagccgcca
601 tgttcatgat tgagatcgca ggcgtgaagc ttttgtacac tggtgatttc tcaagacaag
661 aagataggca cttaatggca gctgaaattc ctaatattaa gcctgatatt cttatcattg
721 aatctactta tgggacccat atccatgaga aacgtgaaga gcgagaagca agattctgta
781 acactgtcca cgatattgta aacagaggag gcaggggtct cattcctgtc tttgctcttg
841 gaagggctca ggagctgctc ttgattctag atgagtactg gcagaatcac ccagaactac
901 atgacattcc aatatactat gcatcatctt tggccaagaa gtgtatggca gtgtaccaga
961 catatgtaaa tgccatgaat gacaaaatcc gcaaacagat caacatcaat aatccctttg
1021 ttttcaaaca cattagtaac ctcaagagca tggatcattt tgatgacatt ggtcccagtg
1081 ttgtaatggc ctccccaggc atgatgcaaa gtggcttatc cagagaatta tttgaaagct
1141 ggtgtactga taagaggaat ggtgtcatta tagcgggata ctgtgtagaa gggacacttg
1201 ccaagcacat catgtctgaa cctgaagaaa tcactactat gtctggacag aagttaccac
1261 tgaaaatgtc tgttgattac atttctttct cagctcacac ggattaccag caaaccagtg
1321 aatttattcg tgctttgaaa ccgcctcatg tgattttagt ccatggagaa cagaatgaaa
1381 tggccagatt gaaagcagca ctgattcgag aatatgaaga taacgatgaa gttcacatag
1441 aggttcataa tcctcggaat acagaagcag tgaccttaaa cttcagagga gaaaaactag
1501 ccaaggttat gggattttta gcagacaaaa aaccagaaca aggccagcgg gtctcaggaa
1561 tacttgttaa aagaaacttt aattatcaca tactttctcc ttgcgacctg tccaattata
1621 ctgacctggc catgagcacg gtgaagcaga cccaagccat tccatatact ggtcccttta
1681 atttgctctg ttaccagctg cagaaattga caggtgatgt ggaagaatta gaaattcaag
1741 aaaaacctgc tctgaaagtg ttcaaaaata ttactgtaat acaagaacca ggcatggtgg
1801 tattagaatg gctggcaaac ccttctaatg atatgtatgc agatacagta acaactgtga
1861 tattggaagt tcagtcaaat cccaaaataa gaaaaggtgc agtacagaag gtttctaaaa
1921 aattagaaat gcacgtttac agcaagaggt tggagatcat gctccaggac atatttggag
1981 aagactgtgt aagtgtaaag gatgactcta ttcttagcgt cacagtggac gggaaaactg
2041 ccaaccttaa cttggagaca cggactgtag aatgtgaaga gggaagtgaa gacgatgaat
2101 ccctccgaga aatggtggag ctggctgcac agagactgta cgaggccctg acgccagttc
2161 actgagactg tgcctgtata tgaactttga aaaaatactt gactctactt ttgttaccta
2221 aaataaaatg cattcgtttc tctgggaaaa aaaaaaaaaa aaaaaaaa
//