LOCUS BC011604 2566 bp mRNA linear HUM 01-JUN-2004
DEFINITION Homo sapiens connector enhancer of kinase suppressor of Ras 1, mRNA
(cDNA clone MGC:1887 IMAGE:3139227), complete cds.
ACCESSION BC011604
VERSION BC011604.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2566)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2566)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC011604.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: k Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 5453622.
FEATURES Location/Qualifiers
source 1..2566
/db_xref="H-InvDB:HIT000035323"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1887 IMAGE:3139227"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2566
/gene="CNKSR1"
/gene_synonym="CNK"
/gene_synonym="CNK1"
/gene_synonym="KSR"
/db_xref="GeneID:10256"
/db_xref="MIM:603272"
CDS 40..2202
/gene="CNKSR1"
/gene_synonym="CNK"
/gene_synonym="CNK1"
/gene_synonym="KSR"
/codon_start=1
/product="CNKSR1 protein"
/protein_id="AAH11604.1"
/db_xref="GeneID:10256"
/db_xref="MIM:603272"
/translation="MEPVETWTPGKVATWLRGLDDSLQDYPFEDWQLPGKNLLQLCPQ
SLEALAVRSLGHQELILGGVEQLQALSSRLQTENLQSLTEGLLGATHDFQSIVQGCLG
DCAKTPIDVLCAAVELLHEADALLFWLSRYLFSHLNDFSACQEIRDLLEELSQVLHED
GPAAEKEGTVLRICSHVAGICHNILVCCPKELLEQKAVLEQVQLDSPLGLEIHTTSNC
QHFVSQVDTQVPTDSRLQIQPGDEVVQINEQVVVREERDMVGWPRKNMVRELLREPAG
LSLVLKKIPIPETPPQTPPQVLDSPHQRSPSLSLAPLSPRAPSEDVFAFDLSSNPSPG
PSPAWTDSASLGPEPLPIPPEPPAILPAGVAGTPGLPESPDKSPVGRKKSKGLATRLS
RRRVSCRELGRPDCDGWLLLRKAPGGFMGPRWRRRWFVLKGHTLYWYRQPQDEKAEGL
INVSNYSLESGHDQKKKYVFQLTHDVYKPFIFAADTLTDLSMWVRHLITCISKYQSPG
RAPPPREEDCYSETEAEDPDDEAGSHSASPSPAQAGSPLHGDTSPAATPTQRSPRTSF
GSLTDSSEEALEGMVRGLRQGGVSLLGQPQPLTQEQWRSSFMRRNRDPQLNERVHRVR
ALQSTLKAKLQELQVLEEVLGDPELTGEKFRQWKEQNRELYSEGLGAWGVAQAEGSSH
ILTSDSTEQSPHSLPSDPEEHSHLCPLTSESSLRPPDL"
BASE COUNT 567 a 815 c 713 g 471 t
ORIGIN
1 ggcaaaacag gagctgattc gagctggcag agctgggcca tggaaccggt agagacctgg
61 acccccggaa aggtggcaac ttggctgaga ggtcttgacg actccctgca ggactatccc
121 tttgaggact ggcagctgcc tggcaagaac ctgctccagc tctgccccca aagcctcgag
181 gctctggctg tgcggtctct gggacaccag gagctcatcc tgggcggggt ggaacagctc
241 caggccctga gctccaggct acagacagag aacctgcaaa gcctgacaga gggacttctg
301 ggggcaaccc atgacttcca gagcatagtc caaggctgcc tgggggactg tgccaagacc
361 cctattgatg tcctctgtgc agctgtggag ctgttgcatg aagctgacgc cctcctcttc
421 tggctcagca ggtacctctt ctcccactta aatgatttct cagcatgcca ggagatccga
481 gacttgttgg aggagctgag ccaggtcttg catgaggatg gtccagcggc tgagaaggag
541 ggcacagtcc tgaggatctg cagccacgtg gctgggatct gccacaacat cctggtctgc
601 tgccccaagg agctgctgga acagaaggcc gtgctcgagc aggtgcagct ggacagtcca
661 ttgggcctag aaattcacac caccagcaat tgccagcact ttgtgtccca agtggacacc
721 caggttccca ctgactcccg actgcagatc cagcctggag acgaggttgt ccagatcaac
781 gagcaggtgg tggtgcgtga ggagagggac atggtgggat ggccccgtaa gaacatggtg
841 agggaactgc tgcgggagcc agccggactc agcttagtgc tgaagaagat cccgataccg
901 gagacccccc cacagacgcc ccctcaggtc ctggactccc cgcaccagag gagcccatca
961 ctgtctctgg ccccactgtc tcccagggcc ccatctgaag acgtctttgc ctttgacctg
1021 tcttcaaacc ccagtcccgg acccagccct gcctggacag actctgcctc ccttggccct
1081 gagcccctgc ccatcccccc ggaaccccca gccatactcc cagcaggggt agcagggact
1141 ccagggctcc ctgaatcccc tgacaagagt cctgttggtc ggaagaaatc aaaaggcctg
1201 gcgacccggc tgagccgccg gcgggtgtca tgccgtgagc tgggccggcc ggactgtgac
1261 ggctggctcc tgttgcgaaa ggcaccgggc ggcttcatgg gcccgcgctg gcgccgccgc
1321 tggtttgtgc tcaagggaca cacgctctac tggtaccgcc agccccagga tgagaaggct
1381 gagggcctca tcaatgtctc caactatagt ctggaaagtg gacatgatca gaagaagaaa
1441 tatgtgtttc agctcaccca tgatgtgtac aaacccttca tcttcgctgc tgataccctg
1501 acagatctga gcatgtgggt gcgtcatctc attacctgca tctccaagta ccagtctcca
1561 ggccgggccc ccccaccccg agaggaagac tgctacagtg agaccgaagc agaggacccg
1621 gacgatgagg ctgggtccca ctcagcctcg cccagccctg ctcaagctgg gagtcccctc
1681 catggagaca catcacctgc agccaccccc acacagcgca gcccacggac ctcctttggc
1741 tctctgacag acagcagtga agaggcactg gaaggaatgg tacgggggct gaggcagggt
1801 ggcgtgtccc tcctaggcca gccacagccc ctgacccagg aacagtggcg gagctctttc
1861 atgcggcgca accgagaccc tcagctcaat gagcgagtgc accgtgtgcg ggcgctacag
1921 agcacactca aggcaaagct gcaggagctg caggtcctag aagaagtgct gggtgaccct
1981 gagctgacag gagagaagtt ccgccagtgg aaggagcaga accgggagct gtactcagag
2041 ggcctggggg cctggggagt ggcacaggct gaaggcagct cccacatctt gacctctgac
2101 tccacagaac agtcccccca ctccctgccc tctgaccctg aagagcactc ccatctctgc
2161 cccctgacct cagagagcag cctccgacct cctgacctct gaccctggcc agcactctag
2221 ctcctgacct ttgacccgag ggccacctca accccagctt ctgacgtgtc caggacagag
2281 catccctgga ttctgttcag ggtgggaagt agtactgcta gtcatggtct caccccgagc
2341 tgacccctct gcctgggctt tgtgccaccc tctcccttgc caaagaagaa actctccccc
2401 caaatcctcc aacctctggg gccacagccc tgcccctcca gttccttggc agttctcccc
2461 caaaccaggt ctgtacaggt gttctttatt ttacatgagg gctactttcc aaccaaataa
2521 agtcaatttt tctaagaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//