LOCUS BC011393 2315 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens chimerin (chimaerin) 1, mRNA (cDNA clone MGC:9243
IMAGE:3871858), complete cds.
ACCESSION BC011393
VERSION BC011393.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2315)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2315)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: k Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 68533258.
FEATURES Location/Qualifiers
source 1..2315
/db_xref="H-InvDB:HIT000035237"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9243 IMAGE:3871858"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2315
/gene="CHN1"
/gene_synonym="ARHGAP2"
/gene_synonym="RHOGAP2"
/db_xref="GeneID:1123"
/db_xref="HGNC:HGNC:1943"
/db_xref="MIM:118423"
CDS 314..1693
/gene="CHN1"
/gene_synonym="ARHGAP2"
/gene_synonym="RHOGAP2"
/codon_start=1
/product="chimerin (chimaerin) 1"
/protein_id="AAH11393.1"
/db_xref="GeneID:1123"
/db_xref="HGNC:HGNC:1943"
/db_xref="MIM:118423"
/translation="MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPK
YYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGK
HFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKH
MPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHW
CEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKA
HTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE
DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCE
TLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVEL
LIKNEDILF"
BASE COUNT 660 a 530 c 539 g 586 t
ORIGIN
1 gccaagcctc ctgcctcgca ggtacctcct cccgcgcgca cgctccgcgc ctgatggcag
61 cgacaagtgc cggctcgcgg agagctagcg gggctccctg ggcccggtgc gcgcacaata
121 acgcgtgaat aactttttct tgcagcggtc ccccgcgtcc cggcctgcag cctccccggg
181 cgccggcgcc cccagcacgc cccatcgggc accccactct ctccgaggtg tgggtgcggc
241 gggctgatga ggtgatccct agcccgcctg ggaggagcgc ctggactcgc gggcggcggc
301 gagcgccttt acaatggccc tgaccctgtt tgatacagat gaatatagac ctcctgtttg
361 gaaatcttac ttatatcagc tacaacagga agcccctcat cctcgaagaa ttacctgtac
421 ttgcgaggtg gaaaacagac caaagtatta tggaagagag tttcatggca tgatctccag
481 agaagcagcc gaccagctct tgattgtggc tgaggggagc tacctcatcc gggagagcca
541 gcggcagcca gggacctaca ctttggcttt aagatttgga agtcaaacca gaaacttcag
601 gctctactac gatggcaagc actttgttgg ggagaaacgc tttgagtcca tccacgatct
661 ggtgactgat ggcttgatta ctctctatat tgaaaccaag gcagcagaat acattgccaa
721 gatgacgata aacccaattt atgagcacgt aggatacaca accttaaaca gagagccagc
781 atacaaaaaa catatgccag tcctgaaaga gacacatgat gagagagatt ctacaggcca
841 ggatggggtg tcagagaaaa ggttgacatc acttgttaga agagcaactc tgaaagaaaa
901 cgagcaaatt ccaaaatatg aaaagattca caatttcaag gtgcatacat tcagagggcc
961 acactggtgt gaatactgtg ccaactttat gtggggtctc attgctcagg gagtgaaatg
1021 tgcagattgt ggtttgaatg ttcataagca gtgttccaag atggtcccaa atgactgtaa
1081 gccagacttg aagcatgtca aaaaggtgta cagctgtgac cttacgacgc tcgtgaaagc
1141 acataccact aagcggccaa tggtggtaga catgtgcatc agggagattg agtctagagg
1201 tcttaattct gaaggactat accgagtatc aggatttagt gacctaattg aagatgtcaa
1261 gatggctttc gacagagatg gtgagaaggc agatatttct gtgaacatgt atgaagatat
1321 caacattatc actggtgcac ttaaactgta cttcagggat ttgccaattc cactcattac
1381 atatgatgcc taccctaagt ttatagaatc tgccaaaatt atggatccgg atgagcaatt
1441 ggaaaccctt catgaagcac tgaaactact gccacctgct cactgcgaaa ccctccggta
1501 cctcatggca catctaaaga gagtgaccct ccacgaaaag gagaatctta tgaatgcaga
1561 gaaccttgga atcgtctttg gacccaccct tatgagatct ccagaactag acgccatggc
1621 tgcattgaat gatatacggt atcagagact ggtggtggag ctgcttatca aaaacgaaga
1681 cattttattt taaattttta atttgagggg aaaagaaatg ttttacagat gaaggaatgt
1741 tttatagtaa tttaatttgc tcctgtagct gcattatttc ttgattagag gtttgggcat
1801 ataaccagat taaagtgaag gaactttctg ttgtttttgt agcaccgctc agctgtcttg
1861 taaaacagtg aacacacgct ttctggttct agtaatcctg ggtgtttatc acgttcagag
1921 aaactcaagc tattgcatga ttagccccct atctggcaag gaaaccccat acagaagaaa
1981 caacaaacct gcgcctgcac cgcctctgcg tcctgggtag tctgtgcttg taatccagca
2041 tgtttcacag agtaagcctg ttgtgacttt gcttttgggg tctatgtcat tggtttctga
2101 tgcttgtaca aacacgcaca cacaaatgga taaaacagca cctctggctg ttacattacc
2161 ataaaccata tcacatgcct acattttaca aatgatttct ggtttctctt agttcttctc
2221 taacatagta ctttctttcc agcaaaagca aaatgtgttt tcagatttgt tactttaata
2281 aaggttatcc ataccaataa aaaaaaaaaa aaaaa
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