LOCUS BC011365 2002 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens glyoxalase I, mRNA (cDNA clone MGC:17245
IMAGE:4182593), complete cds.
ACCESSION BC011365
VERSION BC011365.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2002)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2002)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: l Column: 24.
FEATURES Location/Qualifiers
source 1..2002
/db_xref="H-InvDB:HIT000035220"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17245 IMAGE:4182593"
/tissue_type="Brain, glioblastoma with EGFR amplification"
/clone_lib="NCI_CGAP_Brn64"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2002
/gene="GLO1"
/gene_synonym="GLYI"
/db_xref="GeneID:2739"
/db_xref="HGNC:HGNC:4323"
/db_xref="MIM:138750"
CDS 77..631
/gene="GLO1"
/gene_synonym="GLYI"
/codon_start=1
/product="glyoxalase I"
/protein_id="AAH11365.1"
/db_xref="GeneID:2739"
/db_xref="HGNC:HGNC:4323"
/db_xref="MIM:138750"
/translation="MAEPQPPSGGLTDEAALSYCSDADPSTKDFLLQQTMLRVKDPKK
SLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELT
HNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKG
LAFIQDPDGYWIEILNPNKMATLM"
BASE COUNT 609 a 383 c 401 g 609 t
ORIGIN
1 ggcacagggc cgaggcgtag tgtgggtgac tcctccgttc cttgggtccc gtcgtctgtg
61 atactgcagt gcagccatgg cagaaccgca gcccccgtcc ggcggcctca cggacgaggc
121 cgccctcagt tactgctccg acgcggaccc cagtaccaag gattttctat tgcagcagac
181 catgctacga gtgaaggatc ctaagaagtc actggatttt tatactagag ttcttggaat
241 gacgctaatc caaaaatgtg attttcccat tatgaagttt tcactctact tcttggctta
301 tgaggataaa aatgacatcc ctaaagaaaa agatgaaaaa atagcctggg cgctctccag
361 aaaagctaca cttgagctga cacacaattg gggcactgaa gatgatgaga cccagagtta
421 ccacaatggc aattcagacc ctcgaggatt cggtcatatt ggaattgctg ttcctgatgt
481 atacagtgct tgtaaaaggt ttgaagaact gggagtcaaa tttgtgaaga aacctgatga
541 tggtaaaatg aaaggcctgg catttattca agatcctgat ggctactgga ttgaaatttt
601 gaatcctaac aaaatggcaa ccttaatgta gtgctgtgag aattctcctt tgagatttca
661 gaagaaagga aacaatgtga ttcaagatat ttacatacca gaagcatcta ggactgatgg
721 atcactgtcc cgattcaaat tattcttcag tccatttccc cttcctattt cagctgttcc
781 ttttcaccta actgttcagt cattctggtt ttcaagcagt gctttatctc atgtccttga
841 atatagttgt gtaactttat tttttaggta ataattagaa cagttccctt cagaggctgc
901 atttgccttc ttctgccacc taaatattac ttcccttcaa atctgccttt gaatcatcat
961 ttttaaaaaa aaattaacat gtttttgttg tagttatctt ctggggtttc aattcctcag
1021 aaacaacttt tttcacaacg gaaaggaaag aacactagtg ttctttcagt aaagtacaaa
1081 gtgtttattt tacaaaagag taggtactct tgagagcaat tcaaatcatg ctgacaagga
1141 tactgataga aaaagtgatt tcttcttatt ataaagtaca tttaaagttc aaggactaac
1201 cttatttatt tgggaaaggg gaggaggaag gaaatgatat ggtacccaga cactgggcta
1261 ggctgcaact ttatctcatt taatactccc agctgtcatg tgagaaagaa agcaggctag
1321 gcatgtgaaa tcactttcat ggattattaa tggatttaag agggcatcaa tcagctcaac
1381 tcaagatttc ataatcattt ttagtattta gattgtgcct caaagttgta gtacctcaca
1441 atacctccac tggtttcctg ttgtaaaaac cttcagtgag tttgaccatt gtgctcttgg
1501 ctcttgggct ggagtaccgt ggtgagggag taaacactag aagtctttag tacaaaactg
1561 ctctagggac acctggtgat tcctacacaa gtgatgttta tatttctcat aaagagtctt
1621 ccctatccca aggtcttcat gatgccagta gccatatatg ataaattatg ttcagtgata
1681 acttagttat cagaaatcag ctcagtggtc ttccccgcca tgattcacat ttgatgagtt
1741 tttaaaaatc aaagtgattt tgaaaatctc taatggctca gaaaataaaa acatccagtt
1801 tgtggatgac tatatttaga tttctctaga ctctagtgga agacctttgg aaaggccatg
1861 ccaaccgtgc ttgtactgct agaagcactt tatgtttcct ttttgggtga aatggattta
1921 tgtgagtgct ttaaacaaat agcaatactt atagactgaa ataaaatgaa acttcaaata
1981 agaaaaaaaa aaaaaaaaaa aa
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