LOCUS BC011057 2286 bp mRNA linear HUM 03-NOV-2008
DEFINITION Homo sapiens leucine rich repeat and Ig domain containing 1, mRNA
(cDNA clone MGC:17422 IMAGE:4214343), complete cds.
ACCESSION BC011057
VERSION BC011057.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2286)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2286)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: n Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52145308.
FEATURES Location/Qualifiers
source 1..2286
/db_xref="H-InvDB:HIT000035185"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17422 IMAGE:4214343"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2286
/gene="LINGO1"
/gene_synonym="LERN1"
/gene_synonym="UNQ201"
/db_xref="GeneID:84894"
/db_xref="HGNC:HGNC:21205"
/db_xref="MIM:609791"
CDS 53..1915
/gene="LINGO1"
/gene_synonym="LERN1"
/gene_synonym="UNQ201"
/codon_start=1
/product="leucine rich repeat and Ig domain containing 1"
/protein_id="AAH11057.2"
/db_xref="GeneID:84894"
/db_xref="HGNC:HGNC:21205"
/db_xref="MIM:609791"
/translation="MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPP
RCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELEL
NENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLD
YMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI
VLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLT
AVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGL
NYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQ
QPTCATPEFVQGKEFKDFPDVLLPNYFTCRRARIRDRKAQQVFVDEGHTVQFVCRADG
DPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSM
PAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFI
SFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI"
BASE COUNT 460 a 811 c 600 g 415 t
ORIGIN
1 ggagagacat gcgattggtg accgagccga gcggaccgaa ggcgcgcccg agatgcaggt
61 gagcaagagg atgctggcgg ggggcgtgag gagcatgccc agccccctcc tggcctgctg
121 gcagcccatc ctcctgctgg tgctgggctc agtgctgtca ggctcggcca cgggctgccc
181 gccccgctgc gagtgctccg cccaggaccg cgctgtgctg tgccaccgca agcgctttgt
241 ggcagtcccc gagggcatcc ccaccgagac gcgcctgctg gacctaggca agaaccgcat
301 caaaacgctc aaccaggacg agttcgccag cttcccgcac ctggaggagc tggagctcaa
361 cgagaacatc gtgagcgccg tggagcccgg cgccttcaac aacctcttca acctccggac
421 gctgggtctc cgcagcaacc gcctgaagct catcccgcta ggcgtcttca ctggcctcag
481 caacctgacc aagctggaca tcagcgagaa caagatcgtt atcctactgg actacatgtt
541 tcaggacctg tacaacctca agtcactgga ggttggcgac aatgacctcg tctacatctc
601 tcaccgcgcc ttcagcggcc tcaacagcct ggagcagctg acgctggaga aatgcaacct
661 gacctccatc cccaccgagg cgctgtccca cctgcacggc ctcatcgtcc tgaggctccg
721 gcacctcaac atcaatgcca tccgggacta ctccttcaag aggctgtacc gactcaaggt
781 cttggagatc tcccactggc cctacttgga caccatgaca cccaactgcc tctacggcct
841 caacctgacg tccctgtcca tcacacactg caatctgacc gctgtgccct acctggccgt
901 ccgccaccta gtctatctcc gcttcctcaa cctctcctac aaccccatca gcaccattga
961 gggctccatg ttgcatgagc tgctccggct gcaggagatc cagctggtgg gcgggcagct
1021 ggccgtggtg gagccctatg ccttccgcgg cctcaactac ctgcgcgtgc tcaatgtctc
1081 tggcaaccag ctgaccacac tggaggaatc agtcttccac tcggtgggca acctggagac
1141 actcatcctg gactccaacc cgctggcctg cgactgtcgg ctcctgtggg tgttccggcg
1201 ccgctggcgg ctcaacttca accggcagca gcccacgtgc gccacgcccg agtttgtcca
1261 gggcaaggag ttcaaggact tccctgatgt gctactgccc aactacttca cctgccgccg
1321 cgcccgcatc cgggaccgca aggcccagca ggtgtttgtg gacgagggcc acacggtgca
1381 gtttgtgtgc cgggccgatg gcgacccgcc gcccgccatc ctctggctct caccccgaaa
1441 gcacctggtc tcagccaaga gcaatgggcg gctcacagtc ttccctgatg gcacgctgga
1501 ggtgcgctac gcccaggtac aggacaacgg cacgtacctg tgcatcgcgg ccaacgcggg
1561 cggcaacgac tccatgcccg cccacctgca tgtgcgcagc tactcgcccg actggcccca
1621 tcagcccaac aagaccttcg ctttcatctc caaccagccg ggcgagggag aggccaacag
1681 cacccgcgcc actgtgcctt tccccttcga catcaagacc ctcatcatcg ccaccaccat
1741 gggcttcatc tctttcctgg gcgtcgtcct cttctgcctg gtgctgctgt ttctctggag
1801 ccggggcaag ggcaacacaa agcacaacat cgagatcgag tatgtgcccc gaaagtcgga
1861 cgcaggcatc agctccgccg acgcgccccg caagttcaac atgaagatga tatgaggccg
1921 gggcgggggg cagggacccc cgggcggccg ggcaggggaa ggggcctggc cgccacctgc
1981 tcactctcca gtccttccca cctcctccct acccttctac acacgttctc tttctccctc
2041 ccgcctccgt cccctgctgc cccccgccag ccctcaccac ctgccctcct tctaccagga
2101 cctcagaagc ccagacctgg ggaccccacc tacacagggg cattgacaga ctggagttga
2161 aagccgacga accgacacgc ggcagagtca ataattcaat aaaaaagtta cgaactttct
2221 ctgtaacttg ggtttcaata attatggatt tttatgaaaa cttgaaataa taaaaaaaaa
2281 aaaaaa
//