LOCUS BC011052 3832 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens tripartite motif-containing 2, mRNA (cDNA clone
MGC:18215 IMAGE:4156234), complete cds.
ACCESSION BC011052
VERSION BC011052.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3832)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3832)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: d Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein.
FEATURES Location/Qualifiers
source 1..3832
/db_xref="H-InvDB:HIT000035183"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:18215 IMAGE:4156234"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3832
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/db_xref="GeneID:23321"
CDS 202..2436
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/codon_start=1
/product="TRIM2 protein"
/protein_id="AAH11052.1"
/db_xref="GeneID:23321"
/translation="MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCE
RCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESS
ILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQ
HKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVR
KSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQ
MSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEG
LRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFL
YTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKA
VKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQ
CVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKF
KTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAG
PHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGN
IIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVY
RYLQ"
misc_feature 538..663
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/note="BBOX; Region: B-Box-type zinc finger"
/db_xref="CDD:smart00336"
misc_feature 682..1062
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/note="BBC; Region: B-Box C-terminal domain"
/db_xref="CDD:smart00502"
misc_feature 1174..1464
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 1804..2406
/gene="TRIM2"
/gene_synonym="KIAA0517"
/gene_synonym="RNF86"
/note="COG3391; Region: Uncharacterized conserved protein
[Function unknown]"
/db_xref="CDD:COG3391"
BASE COUNT 1093 a 876 c 905 g 958 t
ORIGIN
1 agcattttga gtgagcttgc agaaaatgag gggctttcag ctggtcgcct gcttgtcacc
61 tctcgctgcc tgaaaggcag ctctcagagc cctttcctgt ccttctaatt acagcggcgg
121 gggcagtgcg cgcttcggga cgcaattgga aaccagcgtg cagggtcaaa gacagccggc
181 cccccatgtc agtggtctag gatggccagt gaaggcacca acatcccaag tcctgtggtg
241 cgccagattg acaagcagtt tctgatttgc agtatatgcc tggaacggta caagaatccc
301 aaggttctcc cctgtctgca cactttctgc gagaggtgcc tgcagaacta cattcctgcc
361 cacagtttaa ccctctcctg cccagtgtgc cgccagacct ccatcctgcc cgagaaaggg
421 gtggccgcgc tccagaacaa tttcttcatc acaaacctga tggacgtgct gcagcgaact
481 ccaggcagca acgctgagga gtcttccatc ctggagacag tcactgctgt ggctgcggga
541 aagcctctct cttgcccaaa ccacgatggg aatgtgatgg aattttactg ccagtcctgt
601 gagactgcca tgtgtcggga gtgcacggag ggggagcacg cagagcaccc cacagttcca
661 ctcaaggatg tggtggaaca gcacaaggcc tcgctccagg tccagctgga tgctgtcaac
721 aaaaggctcc cagaaataga ttctgctctt cagttcatct ctgaaatcat tcatcagtta
781 accaaccaaa aggccagcat cgtggatgac attcattcca cctttgatga gctccagaag
841 actttaaatg tgcgcaagag tgtgctgctt atggaattgg aggtcaacta tggcctcaaa
901 cacaaagtcc tccagtcgca gctggatact ctgctccagg ggcaggagag cattaagagc
961 tgcagcaact tcacagcgca ggccctcaac catggcacgg agaccgaggt cctactggtg
1021 aagaagcaga tgagcgagaa gctgaacgag ctggccgacc aggacttccc cttgcacccg
1081 cgggagaacg accagctgga tttcatcgtg gaaaccgagg ggctgaagaa gtccatccac
1141 aacctcggga cgatcttaac caccaacgcc gttgcctcag agacagtggc cacgggcgag
1201 gggctgcggc agaccatcat cgggcagccc atgtccgtca ccatcaccac caaggacaaa
1261 gacggtgagc tgtgcaaaac cggcaacgcc tacctcaccg ccgaactgag cacccccgac
1321 gggagcgtgg cagacgggga gatcctggac aacaagaacg gcacctatga gtttttgtac
1381 actgtccaga aggaagggga ctttaccctg tctctgagac tctatgacca gcacatccga
1441 ggcagcccgt ttaagctgaa agtgatccga tccgctgatg tgtctcccac cacagaaggc
1501 gtgaagaggc gcgttaagtc cccggggagc ggccacgtca agcagaaagc tgtgaaaaga
1561 cccgcaagca tgtacagcac tggaaaacga aaagagaatc ccatcgaaga cgatttgatc
1621 tttcgagtgg gtaccaaagg aagaaataaa ggagagttta caaatcttca gggggtagct
1681 gcatctacaa atggaaagat attaattgca gacagtaaca accaatgtgt gcagatattt
1741 tccaatgatg gccagttcaa aagtcgtttt ggcatacggg gacgctctcc ggggcagctg
1801 cagcggccca caggagtggc tgtacatccc agtggggaca taatcattgc cgattatgat
1861 aataaatggg tcagcatttt ctcctccgat gggaaattta agacaaaaat tggatcagga
1921 aagctgatgg gacccaaagg agtttctgtg gaccgcaatg ggcacattat tgttgtggac
1981 aacaaggcgt gctgcgtgtt tatcttccag ccaaacggga aaatagtcac caggtttggt
2041 agccgaggaa atggggacag gcagtttgca ggtccccatt ttgcagctgt aaatagcaat
2101 aatgagatta ttattacaga tttccataat cattctgtca aggtgtttaa tcaggaagga
2161 gaattcatgt tgaagtttgg ctcaaatgga gaaggaaatg ggcagtttaa tgctccaaca
2221 ggtgtagcag tggattcaaa tggaaacatc attgtggccg actggggaaa cagcaggatc
2281 caggtttttg atgggagtgg atcatttttg tcctacatta acacatctgc tgacccactc
2341 tatggccccc aaggcctggc cctaacttca gatggtcatg ttgtggttgc agactctgga
2401 aatcactgtt tcaaagtcta tcgatactta cagtaatggt gggcaggtgg atacccgctt
2461 ccatggtctt gcactataaa ctggaatgga tttctcaatg cgggaccaga ttatgactag
2521 agtttttatg ccagaaggaa tcattggtga actttccaag gttatttctg aatgtaacaa
2581 tttccttaaa aatgacttat ccaatttctg tatttcacct ttagggttaa aaaaaactct
2641 tctactgaat ctataaaaac tgcagtttta catctgtgaa ctatggctta agggacagga
2701 tttatgtagc taaactaatt ttgcaaatca aacagacact taaaaaacta gcatatgtaa
2761 aggtattcgt taatcctgtg aatggtagct tttgcacaga acttccaaaa gcaaaacaaa
2821 aacaaaatct attgtagtta tatacttcat ttaacctagg tcacaagacc cagggaatct
2881 tctaacctca cttttacagt aggtattact cttgtgacat ttttttggtt atcaacaact
2941 aaatataaat tactttggaa aaagtaaggc tgtcttgcaa aatgatccca gctctgatta
3001 gcagccctct ggagttcaga acttaagtat cagtgcaaat ttctcaacct ttctgggtta
3061 gacaaagatc cttttttgtg tgttcttttc accacccctt tggctcacct tgtatcagca
3121 aacaaagtac ttcttcaggg aaacctgaaa tttctaatgc cttgaaaagc atattacaaa
3181 agtaatgcta ccttttggga aacaaactgc cccgttaact ccagatcatt gcactggaat
3241 gtaatcaaga aagttagtca tgttttatgt accatgtttt cacacgtgtc tcttctcttc
3301 gacttcctga aagcgaaagc tttacctcct gcaaatgtca gcacatgtag taggacacca
3361 gtatcctagg acagagagcc ataagtagcc ctttggagga ctgatggtgt caaccaaagg
3421 catgtgattg attaatgatt cccccttaga aagcaagtgt taccaaagtt gtgttatctt
3481 gaaagcatta caggtaaggg catgttatgg ttatttatca ttgtttaatg aatagtagag
3541 gtgtcaaggg actatgtata catgattagg gtaagataga atgtattata tatatatata
3601 tatacacaca cacatatata tagctgaatc tttggtgtat tgaaataggc agcactctga
3661 aagacagaag cttcgtccag ccactcttca gcacattcct ttactaagca gtttaaagcc
3721 gtcctagtgg agcaagccct aaagcagatt taatttttgc cattttccaa gaatgacggt
3781 ggtggctttt agtcagaaaa tggccttctg tgctttcaaa aaaaaaaaaa aa
//