LOCUS BC010956 1713 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens fibroblast growth factor 7 (keratinocyte growth
factor), mRNA (cDNA clone MGC:13629 IMAGE:4282925), complete cds.
ACCESSION BC010956
VERSION BC010956.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1713)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1713)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (23-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 19 Row: l Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15147344.
FEATURES Location/Qualifiers
source 1..1713
/db_xref="H-InvDB:HIT000035144"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13629 IMAGE:4282925"
/tissue_type="Brain, primitive neuroectodermal"
/clone_lib="NIH_MGC_56"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1713
/gene="FGF7"
/gene_synonym="HBGF-7"
/gene_synonym="KGF"
/db_xref="GeneID:2252"
/db_xref="MIM:148180"
CDS 471..764
/gene="FGF7"
/gene_synonym="HBGF-7"
/gene_synonym="KGF"
/codon_start=1
/product="FGF7 protein"
/protein_id="AAH10956.1"
/db_xref="GeneID:2252"
/db_xref="MIM:148180"
/translation="MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNV
NCSSPERHTRSYDYMEGEDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYSK"
misc_feature 657..761
/gene="FGF7"
/gene_synonym="HBGF-7"
/gene_synonym="KGF"
/note="FGF; Region: Fibroblast growth factor. Fibroblast
growth factors are a family of proteins involved in growth
and differentiation in a wide range of contexts. These
growth factors cause dimerisation of their tyrosine kinase
receptors leading to intracellular signaling. There are
currently four known tyrosine kinase receptors for
fibroblast growth factors. These receptors can each bind
several different members of this family. Members of this
family have a beta trefoil structure"
/db_xref="CDD:pfam00167"
BASE COUNT 630 a 278 c 284 g 521 t
ORIGIN
1 gggggacaca cacacacaag cacacacgcg ctcacacaca gagagaaaat ccttctgcct
61 gttgatttat ggaaacaatt atgattctgc tggagaactt ttcagctgag aaatagtttg
121 tagctacagt agaaaggctc aagttgcacc aggcagacaa cagacatgga attcttatat
181 atccagctgt tagcaacaaa acaaaagtca aatagcaaac agcgtcacag caactgaact
241 tactacgaac tgtttttatg aggatttatc aacagagtta tttaaggagg aatcctgtgt
301 tgttatcagg aactaaaagg ataaggctaa caatttggaa agagcaacta ctctttctta
361 aatcaatcta caattcacag ataggaagag gtcaatgacc taggagtaac aatcaactca
421 agattcattt tcattatgtt attcatgaac acccggagca ctacactata atgcacaaat
481 ggatactgac atggatcctg ccaactttgc tctacagatc atgctttcac attatctgtc
541 tagtgggtac tatatcttta gcttgcaatg acatgactcc agagcaaatg gctacaaatg
601 tgaactgttc cagccctgag cgacacacaa gaagttatga ttacatggaa ggagaggata
661 taagagtgag aagactcttc tgtcgaacac agtggtacct gaggatcgat aaaagaggca
721 aagtaaaagg gacccaagag atgaagaata attacagtaa gtaattttaa gtactgctca
781 tgaaccttag caatctgtta atggatcaat tttcaggtga catgttttct catcttcctt
841 ttgcttcttg gaaaaaaaat taaataaaat gtcacctaat ttctctaaat tgaactatgt
901 tgaactatgc ccctaaaaat atctctttta acagggcaaa tctacttaca ttatagttgg
961 acctgataat ccaagccaat ttgaaaatat atactccttg tcctgaaaat gctcataagt
1021 taagcaaaat gtaaataata ttattcacac caaaatgtga cttaatattg tctaagcaaa
1081 actcattaag atatctaatt tagaacttca taaattatca ctaaaagcta tttatcacta
1141 gtttaaagag tagggaaatt atttttatta atttgatttt ctttgaaata atattttcat
1201 gatgtaaatt aaaatactta atctgtgcta agatatgcat tcctttgcaa ttgtgtataa
1261 tgataaaata gaagggaatc tgtggtatcc ttattcattt gagtcataat gagcttgtat
1321 taagttgatg acttatcaac ttaggcagaa aaacagatct ctcctaacgt tttccttaac
1381 taaatctttt atgtcataaa agttctgtgc tatcttaaga aaaatgtaaa ggtgagggga
1441 aaaaagtggg ctggaagaga tggtaattcc atgtttttca atttaaagcc ttacattttt
1501 cccaagaatc agttattctt cttatgttaa aatatcaggg ttgtgttttg catttaatgg
1561 ttatgatgaa taaccaactt caatagtatt aaatgtaatg gaataagata cacacctcaa
1621 catgtacatt aaggatttaa aatacttagt aaaaataaat tttgtttaca ttactagcac
1681 tcagaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//