LOCUS BC010860 2207 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serpin peptidase inhibitor, clade E (nexin,
plasminogen activator inhibitor type 1), member 1, mRNA (cDNA clone
MGC:9226 IMAGE:3893914), complete cds.
ACCESSION BC010860
VERSION BC010860.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2207)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2207)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: g Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10835158.
FEATURES Location/Qualifiers
source 1..2207
/db_xref="H-InvDB:HIT000035079"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9226 IMAGE:3893914"
/tissue_type="Lung, carcinoma, large cell
undifferentiated."
/clone_lib="NIH_MGC_69"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2207
/gene="SERPINE1"
/gene_synonym="PAI"
/gene_synonym="PAI-1"
/db_xref="GeneID:5054"
/db_xref="HGNC:HGNC:8583"
/db_xref="MIM:173360"
CDS 123..1331
/gene="SERPINE1"
/gene_synonym="PAI"
/gene_synonym="PAI-1"
/codon_start=1
/product="serpin peptidase inhibitor, clade E (nexin,
plasminogen activator inhibitor type 1), member 1"
/protein_id="AAH10860.1"
/db_xref="GeneID:5054"
/db_xref="HGNC:HGNC:8583"
/db_xref="MIM:173360"
/translation="MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQ
QVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLY
KELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIIN
DWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGS
TVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNI
LSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD
QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT
VLFMGQVMEP"
BASE COUNT 533 a 641 c 559 g 474 t
ORIGIN
1 ggccaagagc gctgtcaaga agacccacac gcccccctcc agcagctgaa ttcctgcagc
61 tcagcagccg ccgccagagc aggacgaacc gccaatcgca aggcacctct gagaacttca
121 ggatgcagat gtctccagcc ctcacctgcc tagtcctggg cctggccctt gtctttggtg
181 aagggtctgc tgtgcaccat cccccatcct acgtggccca cctggcctca gacttcgggg
241 tgagggtgtt tcagcaggtg gcgcaggcct ccaaggaccg caacgtggtt ttctcaccct
301 atggggtggc ctcggtgttg gccatgctcc agctgacaac aggaggagaa acccagcagc
361 agattcaagc agctatggga ttcaagattg atgacaaggg catggccccc gccctccggc
421 atctgtacaa ggagctcatg gggccatgga acaaggatga gatcagcacc acagacgcga
481 tcttcgtcca gcgggatctg aagctggtcc agggcttcat gccccacttc ttcaggctgt
541 tccggagcac ggtcaagcaa gtggactttt cagaggtgga gagagccaga ttcatcatca
601 atgactgggt gaagacacac acaaaaggta tgatcagcaa cttgcttggg aaaggagccg
661 tggaccagct gacacggctg gtgctggtga atgccctcta cttcaacggc cagtggaaga
721 ctcccttccc cgactccagc acccaccgcc gcctcttcca caaatcagac ggcagcactg
781 tctctgtgcc catgatggct cagaccaaca agttcaacta tactgagttc accacgcccg
841 atggccatta ctacgacatc ctggaactgc cctaccacgg ggacaccctc agcatgttca
901 ttgctgcccc ttatgaaaaa gaggtgcctc tctctgccct caccaacatt ctgagtgccc
961 agctcatcag ccactggaaa ggcaacatga ccaggctgcc ccgcctcctg gttctgccca
1021 agttctccct ggagactgaa gtcgacctca ggaagcccct agagaacctg ggaatgaccg
1081 acatgttcag acagtttcag gctgacttca cgagtctttc agaccaagag cctctccacg
1141 tcgcgcaggc gctgcagaaa gtgaagatcg aggtgaacga gagtggcacg gtggcctcct
1201 catccacagc tgtcatagtc tcagcccgca tggcccccga ggagatcatc atggacagac
1261 ccttcctctt tgtggtccgg cacaacccca caggaacagt ccttttcatg ggccaagtga
1321 tggaaccctg accctgggga aagacgcctt catctgggac aaaactggag atgcatcggg
1381 aaagaagaaa ctccgaagaa aagaatttta gtgttaatga ctctttctga aggaagagaa
1441 gacatttgcc ttttgttaaa agatggtaaa ccagatctgt ctccaagacc ttggcctctc
1501 cttggaggac ctttaggtca aactccctag tctccacctg agaccctggg agagaagttt
1561 gaagcacaac tcccttaagg tctccaaacc agacggtgac gcctgcggga ccatctgggg
1621 cacctgcttc cacccgtctc tctgcccact cgggtctgca gacctggttc ccactgaggc
1681 cctttgcagg acggaactac ggggcttaca ggagcttttg tgtgcctggt agaaactatt
1741 tctgttccag tcacattgcc atcactcttg tactgcctgc caccgcggag gaggctggtg
1801 acaggccaaa ggccagtgga agaaacaccc tttcatctca gagtccactg tggcactggc
1861 cacccctccc cagtacaggg gtgctgcagg tggcagagtg aatgtccccc atcatgtggc
1921 ccaactctcc tggcctggcc atctccctcc ccagaaacag tgtgcatggg ttattttgga
1981 gtgtaggtga cttgtttact cattgaagca gatttctgct tccttttatt tttataggaa
2041 tagaggaaga aaggtcagat gcgtgcccag ctcttcaccc cccaatctct tggtggggag
2101 gggtgtacct aaatatttat catatccttg cccttgagtg cttgttagag agaaagagaa
2161 ctactaagga aaataatatt atttaaactc gcaaaaaaaa aaaaaaa
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