LOCUS BC010706 2661 bp mRNA linear HUM 19-APR-2005
DEFINITION Homo sapiens PH domain and leucine rich repeat protein phosphatase,
mRNA (cDNA clone IMAGE:3874711), partial cds.
ACCESSION BC010706
VERSION BC010706.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2661)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2661)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: o Column: 24.
FEATURES Location/Qualifiers
source 1..2661
/db_xref="H-InvDB:HIT000087542"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3874711"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2661
/gene="PHLPP"
/gene_synonym="PLEKHE1"
/gene_synonym="SCOP"
/db_xref="GeneID:23239"
CDS <1..1634
/gene="PHLPP"
/gene_synonym="PLEKHE1"
/gene_synonym="SCOP"
/codon_start=3
/product="PHLPP protein"
/protein_id="AAH10706.1"
/db_xref="GeneID:23239"
/translation="SHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVP
YLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVD
PGGSFTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNG
VTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNV
PDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPP
SVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPPGALSENSP
AYPSEQRCMLHPICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVE
VDIHCSRAKEKEKQQHLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGRRRAN
GSVAPQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQ
EQQQQQQPPPPPQLQPQLPRHYQLDQLPDYYDTPL"
BASE COUNT 666 a 690 c 661 g 644 t
ORIGIN
1 ggagtcatgg ttacactgaa gcttcggggg taaaaaacaa gttgtgtgtc gcagccctgt
61 cggtgaataa cttctgtgac aaccgcgaag ccctgtatgg tgtgtttgac ggagaccgga
121 atgtggaggt gccctacctt ctccagtgca ctatgagtga cattttggct gaagagctgc
181 aaaaaacaaa aaacgaagaa gaatacatgg tcaatacatt cattgtcatg caaaggaaac
241 ttggaactgc tgggcagaag cttggtggtg ccgctgtcct ttgtcatatc aagcatgacc
301 ctgtggatcc aggaggatcc ttcaccttga cctctgctaa tgtgggcaag tgccaaacag
361 ttctctgtcg aaatggaaag ccgctgcctc tgtccagatc ttacatcatg agctgtgaag
421 aagagctgaa gaggattaaa cagcacaagg ccattatcac tgaggatggc aaggtgaacg
481 gagtgactga gtccacgcgc atcctgggct acaccttcct ccatcccagt gtggtgcctc
541 gcccccacgt gcagtccgtg ctcctgactc cccaggatga gttcttcatc ctaggcagta
601 aggggttgtg ggacagcctg tccgtcgagg aggccgtgga agccgtgcgc aacgtgcccg
661 atgccctggc tgctgccaag aagctgtgta ccctggccca gagctacggc tgccacgaca
721 gcatcagcgc tgtggtggtg cagctcagtg tcactgagga cagcttctgc tgctgcgagc
781 tcagcgccgg tggggctgtg ccaccaccca gtcctggcat ctttcctccc tcagtgaaca
841 tggtgatcaa ggatcggccc tcagatgggc tgggcgtgcc gtcctccagc agcggcatgg
901 cttccgagat tagcagtgag ctctccactt ctgagatgag cagcgaggtg gggtcaacag
961 cctccgatga gcccccgccc ggagccctaa gcgagaacag ccctgcctac cccagtgagc
1021 agcgctgcat gctccacccc atctgtctgt ccaactcctt ccagcgccag ctatccagcg
1081 ccacgttctc tagcgccttc tccgacaacg gccttgacag tgacgatgag gagcccatcg
1141 agggcgtctt caccaacggc agccgggtgg aggtggaggt ggacatccac tgcagccggg
1201 ccaaggagaa ggagaaacag cagcacctgc ttcaggtgcc agcagaggcc agtgatgagg
1261 gcattgtcat cagcgccaac gaggatgagc caggtctgcc caggaaggca gacttctctg
1321 ccgttgggac cattgggcgc cggagggcca atggctctgt tgcgccccag gaaaggagcc
1381 acaatgtgat agaggtggct acagacgcac ctcttcgaaa gcctggaggc tattttgctg
1441 ccccggctca gccggatcct gatgatcagt ttatcatacc cccggagctg gaagaggagg
1501 tcaaagaaat catgaagcat caccaggagc aacagcagca gcagcagccg ccaccacccc
1561 ctcagctcca gccgcagctg ccgcggcact accagctgga ccagctgcca gattattacg
1621 acacgccact atgacccagc cgagctgttt aacaaataaa ctaaccacaa aagactgagt
1681 tgcaagagtc tcccaggctc acattaaacc aggggtttta ctccacatcc ttcccccaga
1741 cactgttccc aacctgtcat cgcagctaat ctgtaggttc tctttctttg ggttattttt
1801 ttaagtaatc accactttct tctagtgatg ctttaccaat atgatttaca tttgttaact
1861 tctcccccta acatatcaga tatgtaaaga caaagaacaa aaggtttaat atattacaga
1921 gaaacagtta atgataatgt aatatttttt aaaatggctt tttgttgttt gtttggaagg
1981 cagggcaggc tgccgttgct aaatgattta ataatattgt aattctgtat ttctttgggg
2041 ggaaaaggct tttgttttgt tttgttttgt tttgttttgt ttttgtcttg aaaataatag
2101 acatttgtag aatatggaga ctaactccta ggagttgctt tactctgtca ggtgacttaa
2161 gtcactggga ttcactaatt ttctctgaga gaacagctga ttgagaattt ccattgtaaa
2221 tagctcagtg ttgtatagtg aggcttacga tgttttgtag tcttggcgta aggacacagc
2281 ccaagtaact gacgtttccc ctccccctcc cctctgagga gcctgcctgc ctcacaactc
2341 accctcactt cactgaatga ggaggctgag cagctgcagt gtttctgtcc ggaggaaatg
2401 gatcttaggc cactggacaa gaacctgcac ccaagggccc tgaacccatt ttcctcccct
2461 gtcccagcct tcccactttg acagacactt ttaactgtgt tccttactgc tgccacaatc
2521 agcatggttg tatagtgccc cattaggcca tttacatacc cagagttata ctcaagcaga
2581 atgcacaaat ggacatgtca taatttttgt tacaataaat atgaaattta caagtaaaaa
2641 aaaaaaaaaa aaaaaaaaaa a
//