LOCUS BC010704 2606 bp mRNA linear HUM 24-JUL-2006
DEFINITION Homo sapiens SH2B adaptor protein 1, mRNA (cDNA clone MGC:16976
IMAGE:3866324), complete cds.
ACCESSION BC010704
VERSION BC010704.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2606)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2606)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: e Column: 24.
FEATURES Location/Qualifiers
source 1..2606
/db_xref="H-InvDB:HIT000035054"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:16976 IMAGE:3866324"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2606
/gene="SH2B1"
/gene_synonym="DKFZp547G1110"
/gene_synonym="FLJ30542"
/gene_synonym="SH2-B"
/gene_synonym="SH2B"
/db_xref="GeneID:25970"
/db_xref="HGNC:HGNC:30417"
/db_xref="MIM:608937"
CDS 561..1841
/gene="SH2B1"
/gene_synonym="DKFZp547G1110"
/gene_synonym="FLJ30542"
/gene_synonym="SH2-B"
/gene_synonym="SH2B"
/codon_start=1
/product="SH2B1 protein"
/protein_id="AAH10704.1"
/db_xref="GeneID:25970"
/db_xref="HGNC:HGNC:30417"
/db_xref="MIM:608937"
/translation="MVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQK
CRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVK
VEGPSEYIMETVDAQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTD
SLELSCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFD
SMELLPPELPPRIPIEEGPPAGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQP
LSGYPWFHGMLSRLKAAQLALTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRL
SLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQA
GSHAGVCEGDGCHPDASCTLMPFGASDCVTDHLP"
BASE COUNT 497 a 811 c 801 g 497 t
ORIGIN
1 gggccgaggc tgccttctcc cgccgttttg ctgagctctt cctgcagcac tttgaagccg
61 aggtggcccg ggcctctggc tccctgtcgc cacccatcct ggctcccctg agccctggtg
121 cggagatttc gccacatgac ctgtcccttg agagctgcag ggtgggtggg cccctggctg
181 tgctgggccc ttctcgatca tctgaggacc tggccggccc cctcccttcc tcagtctctt
241 cctcctctac aacctcctcc aagccgaagc tcaagaagcg cttttccctg cgttcagtgg
301 gtcgctctgt ccgaggctca gtccgtggca tcctgcagtg gcgggggacc gttgaccctc
361 cctcctccgc tgggcccctg gagacctcgt caggcccccc agtcttaggt ggaaacagca
421 actccaactc ctctggcggg gctgggaccg ttggtagggg actggtcagt gatggaacgt
481 cccctgggga aagatggact caccgttttg agaggctgag actcagtcgg ggagggggcg
541 ccttgaagga tggagcaggg atggtgcaga gggaagagct gctgagtttc atgggggctg
601 aggaggcagc ccctgaccca gccggagtgg gccggggagg aggggtggct gggcctcctt
661 cagggggagg agggcagcct cagtggcaga agtgtcgcct gctgcttcga agtgaaggag
721 aaggaggagg aggaagtcgc ctggagttct ttgtaccacc caaggcctct cggccccgac
781 tcagcatccc ctgctcttct atcacagacg tccggacaac cacagccctg gagatgcctg
841 accgggagaa cacgtttgtg gttaaggtgg aaggtccatc cgagtatatc atggagacag
901 tggatgccca gcatgtgaag gcctgggtgt ctgacatcca agaatgcctg agcccaggac
961 cctgccctgc taccagtccc cgccccatga ccctccctct ggcccctggg acctcattcc
1021 ttacaaggga gaacacagac agcctggagc tgtcctgcct gaatcactcg gagagtctac
1081 ccagccagga cctgctgctt ggacccagcg agagcaatga ccgcctgtcg cagggggcat
1141 atgggggcct ctcagaccgc ccctcggcat ccatctcccc cagctctgcc tccattgccg
1201 cctcccattt tgactcgatg gaactgcttc ccccagagtt gcccccccgc atccccattg
1261 aagagggacc cccagcaggg acagttcatc ccctctcagc cccctaccct cccttggaca
1321 ctccggaaac agccacaggg tccttcctgt tccaggggga gccagagggc ggtgaggggg
1381 accagcccct ctcagggtat ccttggttcc acgggatgct ctctcggctc aaggctgcac
1441 agttggcgct gactggcggc actggctccc acggtgtctt cctggtgcgc cagagtgaga
1501 caaggcgggg tgaatacgtc ctcaccttca acttccaggg caaggccaag cacctgcgtt
1561 tgtcgctgaa cgaggagggt cagtgccggg tccagcacct gtggttccag tccattttcg
1621 atatgctcga gcacttccgg gtgcacccca tccctttgga gtcgggaggc tccagtgatg
1681 ttgtccttgt cagctatgtc ccatcctccc agcgacagca gggccgggag caggctggga
1741 gccatgcggg ggtgtgcgag ggagatggat gccaccccga tgcctcctgc accctcatgc
1801 ccttcggagc gagtgactgt gtaaccgacc acctcccatg acccacccca gccccctgaa
1861 cccccttcat ggacagatcc cccacagcct ggggcagaag aggcgtcgag ggcgccagaa
1921 gtggcggcag cagcagccgc agcagccaaa gagaggcaag agaaagagaa agcgggcggt
1981 ggaggggtcc cggaagagct ggtccccgtg gttgagctgg tccccgtggt tgaattggaa
2041 gaggccatag ccccaggctc agaggcccag ggcgctgggt ctggtgggga cgcgggggtg
2101 cccccaatgg tgcagctgca gcagtcacca ctagggggtg atggagagga agggggccac
2161 cccagggcca ttaacaacca gtactccttc gtgtgagcca accccacccg ctccaccctt
2221 tttaaacccc ccagccctgc tcgtgagatt gggctgggta gggacagagg aggccgaaat
2281 ccctccccca tgcttcctga cccttgttgg ccaagggcat ctttgatggt acaagcagag
2341 gctcgggaga ggctcccgtc acacactaca ggtcccctcc ccagggcagg ggatttgggc
2401 tccatgagct ccttgagggg ctcttctggt cagccccacc ctgggggcca tttccccatt
2461 aactaccccc agcccgaggc agggtgaggg ggaagggctg tcagttacat taaggtggtt
2521 gttgttgttg ttttaaacaa aatggagaag cataaataaa taaaaaggtt tatctcggtt
2581 ctatcgtgaa aaaaaaaaaa aaaaaa
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