LOCUS BC010611 2031 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fibroblast growth factor receptor substrate 3, mRNA
(cDNA clone MGC:17167 IMAGE:4183414), complete cds.
ACCESSION BC010611
VERSION BC010611.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2031)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2031)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: l Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31657134.
FEATURES Location/Qualifiers
source 1..2031
/db_xref="H-InvDB:HIT000035010"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17167 IMAGE:4183414"
/tissue_type="Brain, glioblastoma with EGFR amplification"
/clone_lib="NCI_CGAP_Brn64"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2031
/gene="FRS3"
/gene_synonym="FRS2B"
/gene_synonym="FRS2beta"
/gene_synonym="MGC17167"
/gene_synonym="SNT-2"
/gene_synonym="SNT2"
/db_xref="GeneID:10817"
/db_xref="HGNC:HGNC:16970"
/db_xref="MIM:607744"
CDS 76..1554
/gene="FRS3"
/gene_synonym="FRS2B"
/gene_synonym="FRS2beta"
/gene_synonym="MGC17167"
/gene_synonym="SNT-2"
/gene_synonym="SNT2"
/codon_start=1
/product="fibroblast growth factor receptor substrate 3"
/protein_id="AAH10611.1"
/db_xref="GeneID:10817"
/db_xref="HGNC:HGNC:16970"
/db_xref="MIM:607744"
/translation="MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSE
LVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQ
DLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSA
PRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAP
FLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAP
SECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWES
QAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTR
RRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPAR
SSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL"
BASE COUNT 427 a 649 c 546 g 409 t
ORIGIN
1 gaacccttcc ccatgcccct cccacggtca gctccccgat ggcctgggtg agggcaggct
61 ggctgctctg acaccatggg gagctgctgc agctgcctga acagagacag cgttccagac
121 aaccacccca ccaagttcaa ggtgacaaat gtggatgatg agggggtgga gctgggctct
181 ggggtgatgg agctgacgca gagtgagctg gtgctgcacc tgcatcggcg tgaggccgtc
241 cgctggcctt atctctgctt gcggcgctat ggctacgact ccaacctctt ctcctttgag
301 agtggccgcc gatgtcagac aggccaggga atatttgcat ttaagtgttc ccgggctgag
361 gaaatcttca acctccttca ggatctgatg cagtgcaaca gcatcaatgt gatggaagag
421 cctgtcatca tcacccgcaa tagccacccc gctgagcttg acctccctcg agccccccag
481 ccacccaatg ctctaggcta cactgtctcc agcttttcca atggctgccc tggagagggc
541 ccacgattct cagctccccg gcggctctcg acaagcagcc tgcggcaccc ctcgcttggg
601 gaagagtcca cccatgccct cattgctcct gatgagcagt cccacaccta tgtcaacaca
661 ccggccagtg aagatgacca ccgcaggggc cgccactgcc tgcagcccct gcctgagggt
721 caggcaccct tcctcccgca ggcccgggga cctgaccaac gggacccaca ggtgttcttg
781 cagccaggcc aggtgaagtt tgtgttgggc ccgacccctg ctcggcggca catggtgaag
841 tgccagggcc tctgtcccag cctgcatgac cccccacacc acaataataa caatgaggcc
901 ccttctgagt gtccagccca gcccaagtgc acctacgaga acgtcaccgg ggggctgtgg
961 cgaggggctg gctggagact gagcccagag gagccgggct ggaatggcct tgcccaccgc
1021 cgggccgccc tgctgcacta tgagaacctg cccccactgc cccctgtgtg ggaaagccaa
1081 gcccagcagc tgggagggga ggctggggat gatggggact cgagggatgg gctcacaccc
1141 tcttccaatg gcttccctga tggtgaggag gacgagaccc cactgcagaa gcccaccagc
1201 acccgggccg ccatccgcag ccacggcagc tttcctgtgc cactgacccg ccgccgcggc
1261 tccccaaggg tcttcaactt tgatttccgc cggccggggc ccgagccccc aaggcagctt
1321 aactacatcc aggtggagct aaagggctgg ggtggagacc gccctaaggg gccccagaac
1381 ccctcgagcc cccaagcccc catgcccacc acccaccctg cccgaagctc agactcctac
1441 gccgtgattg acctcaaaaa gaccgtggcc atgtccaacc tgcagagagc tctgccccga
1501 gacgatggca ccgccaggaa aacccggcac aacagcaccg acctgcctct gtagggactt
1561 cccggtcctc accaccctct gccccaccat gatccagcct ctgcctcaca ctcctgtcct
1621 ctgaacccac cctccccagg gttcagggtt gctttgcaga aggcatggag gtgggaccag
1681 atgcttccct gtgctggctg gagtccccag agatatcagc caccgagtct cctggtctgt
1741 ctccaggctg ggaagagaag ggtgaccagg cgaggaggga gccgagacgt caactgtgaa
1801 gggttcctgt gattgcgttt agcgccctcc cgttctgtcc atttgtcttg tctgccgact
1861 gtccgtgtgt gttttttttg gttggaattt tgaaacattt tgtacctgtt gattttattt
1921 atcagtttat ttttctattt attgttttaa atgtaattta acatatttat tattaatata
1981 attattttta aattctgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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