LOCUS BC010577 2111 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens granulin, mRNA (cDNA clone MGC:9342 IMAGE:3457813),
complete cds.
ACCESSION BC010577
VERSION BC010577.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2111)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2111)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC010577.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: a Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 60498993.
FEATURES Location/Qualifiers
source 1..2111
/db_xref="H-InvDB:HIT000035006"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9342 IMAGE:3457813"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2111
/gene="GRN"
/gene_synonym="GEP"
/gene_synonym="GP88"
/gene_synonym="PCDGF"
/gene_synonym="PEPI"
/db_xref="GeneID:2896"
/db_xref="HGNC:HGNC:4601"
/db_xref="MIM:138945"
CDS 11..1792
/gene="GRN"
/gene_synonym="GEP"
/gene_synonym="GP88"
/gene_synonym="PCDGF"
/gene_synonym="PEPI"
/codon_start=1
/product="granulin"
/protein_id="AAH10577.1"
/db_xref="GeneID:2896"
/db_xref="HGNC:HGNC:4601"
/db_xref="MIM:138945"
/translation="MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRP
LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRG
FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCED
RVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDG
STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPA
HTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGT
CEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIP
EAVCCSDHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSC
PVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFL
ARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCA
ARGTKCLRREAPRWDAPLRDPALRQLL"
BASE COUNT 378 a 681 c 627 g 425 t
ORIGIN
1 caggcagacc atgtggaccc tggtgagctg ggtggcctta acagcagggc tggtggctgg
61 aacgcggtgc ccagatggtc agttctgccc tgtggcctgc tgcctggacc ccggaggagc
121 cagctacagc tgctgccgtc cccttctgga caaatggccc acaacactga gcaggcatct
181 gggtggcccc tgccaggttg atgcccactg ctctgccggc cactcctgca tctttaccgt
241 ctcagggact tccagttgct gccccttccc agaggccgtg gcatgcgggg atggccatca
301 ctgctgccca cggggcttcc actgcagtgc agacgggcga tcctgcttcc aaagatcagg
361 taacaactcc gtgggtgcca tccagtgccc tgatagtcag ttcgaatgcc cggacttctc
421 cacgtgctgt gttatggtcg atggctcctg ggggtgctgc cccatgcccc aggcttcctg
481 ctgtgaagac agggtgcact gctgtccgca cggtgccttc tgcgacctgg ttcacacccg
541 ctgcatcaca cccacgggca cccaccccct ggcaaagaag ctccctgccc agaggactaa
601 cagggcagtg gccttgtcca gctcggtcat gtgtccggac gcacggtccc ggtgccctga
661 tggttctacc tgctgtgagc tgcccagtgg gaagtatggc tgctgcccaa tgcccaacgc
721 cacctgctgc tccgatcacc tgcactgctg cccccaagac actgtgtgtg acctgatcca
781 gagtaagtgc ctctccaagg agaacgctac cacggacctc ctcactaagc tgcctgcgca
841 cacagtgggg gatgtgaaat gtgacatgga ggtgagctgc ccagatggct atacctgctg
901 ccgtctacag tcgggggcct ggggctgctg cccttttacc caggctgtgt gctgtgagga
961 ccacatacac tgctgtcccg cggggtttac gtgtgacacg cagaagggta cctgtgaaca
1021 ggggccccac caggtgccct ggatggagaa ggccccagct cacctcagcc tgccagaccc
1081 acaagccttg aagagagatg tcccctgtga taatgtcagc agctgtccct cctccgatac
1141 ctgctgccaa ctcacgtctg gggagtgggg ctgctgtcca atcccagagg ctgtctgctg
1201 ctcggaccac cagcactgct gcccccaggg ctacacgtgt gtagctgagg ggcagtgtca
1261 gcgaggaagc gagatcgtgg ctggactgga gaagatgcct gcccgccggg cttccttatc
1321 ccaccccaga gacatcggct gtgaccagca caccagctgc ccggtggggc agacctgctg
1381 cccgagcctg ggtgggagct gggcctgctg ccagttgccc catgctgtgt gctgcgagga
1441 tcgccagcac tgctgcccgg ctggctacac ctgcaacgtg aaggctcgat cctgcgagaa
1501 ggaagtggtc tctgcccagc ctgccacctt cctggcccgt agccctcacg tgggtgtgaa
1561 ggacgtggag tgtggggaag gacacttctg ccatgataac cagacctgct gccgagacaa
1621 ccgacagggc tgggcctgct gtccctaccg ccagggcgtc tgttgtgctg atcggcgcca
1681 ctgctgtcct gctggcttcc gctgcgcagc caggggtacc aagtgtttgc gcagggaggc
1741 cccgcgctgg gacgcccctt tgagggaccc agccttgaga cagctgctgt gagggacagt
1801 actgaagact ctgcagccct cgggacccca ctcggagggt gccctctgct caggcctccc
1861 tagcacctcc ccctaaccaa attctccctg gaccccattc tgagctcccc atcaccatgg
1921 gaggtggggc ctcaatctaa ggccttccct gtcagaaggg ggttgtggca aaagccacat
1981 tacaagctgc catcccctcc ccgtttcagt ggaccctgtg gccaggtgct tttccctatc
2041 cacaggggtg tttgtgtgtg tgcgcgtgtg cgtttcaata aagtttgtac actttcaaaa
2101 aaaaaaaaaa a
//