LOCUS BC010514 1684 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens clusterin, mRNA (cDNA clone MGC:18080 IMAGE:4150452),
complete cds.
ACCESSION BC010514
VERSION BC010514.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1684)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1684)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 19 Row: o Column: 12.
FEATURES Location/Qualifiers
source 1..1684
/db_xref="H-InvDB:HIT000034978"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:18080 IMAGE:4150452"
/tissue_type="Brain, glioblastoma with EGFR amplification"
/clone_lib="NCI_CGAP_Brn64"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1684
/gene="CLU"
/gene_synonym="AAG4"
/gene_synonym="KUB1"
/gene_synonym="MGC24903"
/gene_synonym="SGP-2"
/gene_synonym="SGP2"
/gene_synonym="SP-40"
/gene_synonym="TRPM-2"
/gene_synonym="TRPM2"
/db_xref="GeneID:1191"
/db_xref="HGNC:HGNC:2095"
/db_xref="MIM:185430"
CDS 69..1418
/gene="CLU"
/gene_synonym="AAG4"
/gene_synonym="KUB1"
/gene_synonym="MGC24903"
/gene_synonym="SGP-2"
/gene_synonym="SGP2"
/gene_synonym="SP-40"
/gene_synonym="TRPM-2"
/gene_synonym="TRPM2"
/codon_start=1
/product="CLU protein"
/protein_id="AAH10514.1"
/db_xref="GeneID:1191"
/db_xref="HGNC:HGNC:2095"
/db_xref="MIM:185430"
/translation="MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNK
EIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVC
NETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRID
SLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHF
FFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIR
EGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVA
ERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASH
TSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE"
BASE COUNT 433 a 493 c 448 g 310 t
ORIGIN
1 cgccaggagg agcgcgcggg cacagggtgc cgctgaccga ggcgtgcaaa gactccagaa
61 ttggaggcat gatgaagact ctgctgctgt ttgtggggct gctgctgacc tgggagagtg
121 ggcaggtcct gggggaccag acggtctcag acaatgagct ccaggaaatg tccaatcagg
181 gaagtaagta cgtcaataag gaaattcaaa atgctgtcaa cggggtgaaa cagataaaga
241 ctctcataga aaaaacaaac gaagagcgca agacactgct cagcaaccta gaagaagcca
301 agaagaagaa agaggatgcc ctaaatgaga ccagggaatc agagacaaag ctgaaggagc
361 tcccaggagt gtgcaatgag accatgatgg ccctctggga agagtgtaag ccctgcctga
421 aacagacctg catgaagttc tacgcacgcg tctgcagaag tggctcaggc ctggttggcc
481 gccagcttga ggagttcctg aaccagagct cgcccttcta cttctggatg aatggtgacc
541 gcatcgactc cctgctggag aacgaccggc agcagacgca catgctggat gtcatgcagg
601 accacttcag ccgcgcgtcc agcatcatag acgagctctt ccaggacagg ttcttcaccc
661 gggagcccca ggatacctac cactacctgc ccttcagcct gccccaccgg aggcctcact
721 tcttctttcc caagtcccgc atcgtccgca gcttgatgcc cttctctccg tacgagcccc
781 tgaacttcca cgccatgttc cagcccttcc ttgagatgat acacgaggct cagcaggcca
841 tggacatcca cttccacagc ccggccttcc agcacccgcc aacagaattc atacgagaag
901 gcgacgatga ccggactgtg tgccgggaga tccgccacaa ctccacgggc tgcctgcgga
961 tgaaggacca gtgtgacaag tgccgggaga tcttgtctgt ggactgttcc accaacaacc
1021 cctcccaggc taagctgcgg cgggagctcg acgaatccct ccaggtcgct gagaggttga
1081 ccaggaaata caacgagctg ctaaagtcct accagtggaa gatgctcaac acctcctcct
1141 tgctggagca gctgaacgag cagtttaact gggtgtcccg gctggcaaac ctcacgcaag
1201 gcgaagacca gtactatctg cgggtcacca cggtggcttc ccacacttct gactcggacg
1261 ttccttccgg tgtcactgag gtggtcgtga agctctttga ctctgatccc atcactgtga
1321 cggtccctgt agaagtctcc aggaagaacc ctaaatttat ggagaccgtg gcggagaaag
1381 cgctgcagga ataccgcaaa aagcaccggg aggagtgaga tgtggatgtt gcttttgcac
1441 ctacgggggc atctgagtcc agctcccccc aagatgagct gcagcccccc agagagagct
1501 ctgcacgtca ccaagtaacc aggccccagc ctccaggccc ccaactccgc ccagcctctc
1561 cccgctctgg atcctgcact ctaacactcg actctgctgc tcatgggaag aacagaattg
1621 ctcctgcatg caactaattc aataaaactg tcttgtgagc tgaaaaaaaa aaaaaaaaaa
1681 aaaa
//