LOCUS BC010437 2798 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens kelch-like 23 (Drosophila), mRNA (cDNA clone MGC:2610
IMAGE:3354344), complete cds.
ACCESSION BC010437
VERSION BC010437.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2798)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2798)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: p Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40255070.
FEATURES Location/Qualifiers
source 1..2798
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2610 IMAGE:3354344"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2798
/gene="KLHL23"
/gene_synonym="FLJ37812"
/gene_synonym="MGC22679"
/gene_synonym="MGC2610"
/db_xref="GeneID:151230"
/db_xref="HGNC:HGNC:27506"
CDS 79..1755
/gene="KLHL23"
/gene_synonym="FLJ37812"
/gene_synonym="MGC22679"
/gene_synonym="MGC2610"
/codon_start=1
/product="KLHL23 protein"
/protein_id="AAH10437.2"
/db_xref="GeneID:151230"
/db_xref="HGNC:HGNC:27506"
/translation="MALKGQEDYIYLFKDSTHPVDFLDAFRTFYLDGLFTDITLQCPS
GIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKLSGIHHDILEGLVNYAYTSQIEI
TKRNVQSLLEAADLLQFLSVKKACERFLVRHLDIDNCIGMHSFAEFHVCPELEKESRR
ILCSKFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAIIEPVIKWTAHDVENRIEC
LYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMY
IIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIE
ALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPL
KEKWIPIANMIKGVGNATACVLHDVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLIT
SSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNG
CIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV"
BASE COUNT 870 a 467 c 602 g 859 t
ORIGIN
1 gaggggccgg aggcgtcccc gctcccgctc gctactagcc cgcgggccag cgccgcgtcc
61 cgagccccgg cgggagccat ggctctaaaa ggacaagaag attatattta tcttttcaag
121 gattcaacac atccagtgga ttttctggat gcattcagaa cattttactt ggatggatta
181 tttactgata ttactcttca gtgtccttca ggcataattt tccattgtca ccgagccgtt
241 ttagctgctt gcagcaatta ttttaaggca atgttcacag ctgacatgaa agaaaaattt
301 aaaaataaaa taaaactctc tggcatccac catgatattc tggaaggcct tgtaaattat
361 gcatacactt cccaaattga aataactaaa agaaatgttc aaagcctgct tgaggcagcg
421 gatctgctac agttcctttc agtaaagaag gcttgtgagc ggtttttggt aaggcacttg
481 gatattgata attgtattgg aatgcactcc tttgcagaat ttcatgtgtg tccagaacta
541 gagaaggaat ctcgaagaat tctatgttca aagtttaagg aagtgtggca acaagaagaa
601 tttctggaaa tcagccttga aaagtttctc tttatcttgt ccagaaagaa tctcagtgtt
661 tggaaagaag aagctatcat agagccagtt attaagtgga ctgctcatga tgtagaaaat
721 cgaattgaat gcctctataa tctactgagc tatatcaaca ttgatataga tccagtgtac
781 ttaaaaacag ccttaggcct tcaaagaagc tgcctgctca ccgaaaataa gatccgctcc
841 ctaatataca atgccttgaa tcccatgcat aaagagattt cccagaggtc cacagccaca
901 atgtatataa ttggaggcta ttactggcat cctttatcag aggttcacat atgggatcct
961 ttgacaaatg tttggattca gggagcagaa ataccagatt ataccaggga gagctatggt
1021 gttacatgtt taggacccaa catttatgta actgggggct acaggacgga taacatagaa
1081 gctcttgaca cagtgtggat ctataacagt gaaagtgatg aatggacaga aggtttgcca
1141 atgctcaatg ccaggtatta ccactgtgca gtcaccttgg gtggctgtgt ctatgcttta
1201 ggtggttaca gaaaaggggc tccagcagaa gaggctgagt tctatgatcc tttaaaagag
1261 aaatggattc ctattgcaaa catgattaaa ggtgtgggaa atgctactgc ctgtgtctta
1321 catgatgtta tctacgtcat tggtggccac tgtggctaca gaggaagctg cacctatgac
1381 aaagttcaga gctacaattc cgatatcaac gaatggagcc tcatcacctc cagtccacat
1441 ccagaatatg gattgtgctc agttccgttt gaaaataagc tctatctagt cggtggacaa
1501 actacaatca cagaatgcta tgaccctgaa caaaatgaat ggagagagat agctcccatg
1561 atggaaagga ggatggagtg cggtgccgtc atcatgaatg gatgtattta tgtcactgga
1621 ggatactcct actcaaaggg aacgtatctt cagagcattg agaaatatga tccagatctt
1681 aataagtggg aaatagtggg taatcttccc agtgccatgc ggtctcatgg gtgtgtttgt
1741 gtgtataatg tctaattgaa tctgcagaaa tgaccaagca atcacttttt tggagtatag
1801 ttttataaaa aaagaatgca gggtttgaag ttccttacct gataattgtg tctggcacat
1861 gataggggat cagtaaattg taattcctaa ccctactgta ctcccaaaca tggtgattca
1921 tggtcaagaa aaatcttata tatatatata cacacacata tatatgtgtt catatatatg
1981 tatacatata tgtgtatata tacgcatgta tgtatacata tatgtgtata tatacgcatg
2041 tatgtatgca tatgtgtgta tatatacgta tgtatgtata catatgtgta tatatacgta
2101 tgtatgtata catatatgtg tatatatgcg tatgtatgta tacatatatg tgtatatata
2161 cgtatgtatg tatacatata tgtgtatata tacgtatgta tgtatacata tatgtgtata
2221 tatacgtatg tatgtataca tatatgtgtg tatatacgtg tgtatgtata catatatgtg
2281 tatatatacg tgtgtatgta tacatatatg tgtatatatg cgtgtgtatg tatacatata
2341 tgtgtatata tacgtgtgta tgtatacata tatgtgtata tatacgtgtg tatgtataca
2401 tatatgtgta tatatgcgtg tgtatatata tacacatata tacgtatata tgtatatata
2461 tatacacagt tgaatcagtg ggattaatac ctataatctc tggttttcaa aggtaatatg
2521 gaatatttga cacttggtaa aaggtgaact acctttgtag tgaatctttt cctcttggta
2581 gcatcaacac tggggataaa tcagaaccat tctgtggaat gaaatgtttc tcaagagcct
2641 ataatatagt agatagtgca tattaagatg tctggctggg catggtggct catgcctgta
2701 atcccagcac tttgggaggc tgaggcggga ggatcacttg agcctagaag ttggagacta
2761 acctggcgag accctgtctc aaaaaaaaaa aaaaaaaa
//