LOCUS BC010391 1391 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member B1 (aldose
reductase), mRNA (cDNA clone MGC:13648 IMAGE:4049736), complete
cds.
ACCESSION BC010391
VERSION BC010391.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1391)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1391)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 19 Row: c Column: 4.
FEATURES Location/Qualifiers
source 1..1391
/db_xref="H-InvDB:HIT000034914"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13648 IMAGE:4049736"
/tissue_type="Brain, primitive neuroectodermal"
/clone_lib="NIH_MGC_56"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1391
/gene="AKR1B1"
/gene_synonym="ADR"
/gene_synonym="AR"
/gene_synonym="MGC1804"
/db_xref="GeneID:231"
/db_xref="HGNC:HGNC:381"
/db_xref="MIM:103880"
CDS 41..991
/gene="AKR1B1"
/gene_synonym="ADR"
/gene_synonym="AR"
/gene_synonym="MGC1804"
/codon_start=1
/product="aldo-keto reductase family 1, member B1 (aldose
reductase)"
/protein_id="AAH10391.1"
/db_xref="GeneID:231"
/db_xref="HGNC:HGNC:381"
/db_xref="MIM:103880"
/translation="MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHID
CAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKL
DYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGIS
NFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR
PWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKV
FDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF"
BASE COUNT 350 a 353 c 371 g 317 t
ORIGIN
1 ggggaccgta ctgggcgggg gtctggggag cgcagcagcc atggcaagcc gtctcctgct
61 caacaacggc gccaagatgc ccatcctggg gttgggtacc tggaagtccc ctccagggca
121 ggtgactgag gccgtgaagg tggccattga cgtcgggtac cgccacatcg actgtgccca
181 tgtgtaccag aatgagaatg aggtgggggt ggccattcag gagaagctca gggagcaggt
241 ggtgaagcgt gaggagctct tcatcgtcag caagctgtgg tgcacgtacc atgagaaggg
301 cctggtgaaa ggagcctgcc agaagacact cagcgacctg aagctggact acctggacct
361 ctaccttatt cactggccga ctggctttaa gcctgggaag gaatttttcc cattggatga
421 gtcgggcaat gtggttccca gtgacaccaa cattctggac acgtgggcgg ccatggaaga
481 gctggtggat gaagggctgg tgaaagctat tggcatctcc aacttcaacc atctccaggt
541 ggagatgatc ttaaacaaac ctggcttgaa gtataagcct gcagttaacc agattgagtg
601 ccacccatat ctcactcagg agaagttaat ccagtactgc cagtccaaag gcatcgtggt
661 gaccgcctac agccccctcg gctctcctga caggccctgg gccaagcccg aggacccttc
721 tctcctggag gatcccagga tcaaggcgat cgcagccaag cacaataaaa ctacagccca
781 ggtcctgatc cggttcccca tgcagaggaa cttggtggtg atccccaagt ctgtgacacc
841 agaacgcatt gctgagaact ttaaggtctt tgactttgaa ctgagcagcc aggatatgac
901 caccttactc agctacaaca ggaactggag ggtctgtgcc ttgttgagct gtacctccca
961 caaggattac cccttccatg aagagttttg aagctgtggt tgcctgctcg tccccaagtg
1021 acctatacct gtgtttcttg cctcattttt ttccttgcaa atgtagtatg gcctgtgtca
1081 ctcagcagtg ggacagcaac ctgtagagtg gccagcgagg gcgtgtctag cttgatgttg
1141 gatctcaaga gccctgtcag tagagtagaa gtctcttcca gtttgctttg cccttctttc
1201 taccctgctg gggaaagtac aacctgaata cccttttctg accaaagaga agcaaaatct
1261 accaggtcaa aatagtgcca ctaacggttg agttttgact gcttggaact ggaatccttt
1321 cagcaagact tctctttgcc tcaaataaaa agtgcttttg tcaaaaaaaa aaaaaaaaaa
1381 aaaaaaaaaa a
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