LOCUS BC010153 1361 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase 4, mRNA (cDNA clone MGC:19704
IMAGE:3531300), complete cds.
ACCESSION BC010153
VERSION BC010153.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1361)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1361)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC010153.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 27 Row: d Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1361
/db_xref="H-InvDB:HIT000034841"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19704 IMAGE:3531300"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1361
/gene="CDK4"
/gene_synonym="CMM3"
/gene_synonym="MGC14458"
/gene_synonym="PSK-J3"
/db_xref="GeneID:1019"
/db_xref="HGNC:HGNC:1773"
/db_xref="MIM:123829"
CDS 142..1053
/gene="CDK4"
/gene_synonym="CMM3"
/gene_synonym="MGC14458"
/gene_synonym="PSK-J3"
/codon_start=1
/product="cyclin-dependent kinase 4"
/protein_id="AAH10153.1"
/db_xref="GeneID:1019"
/db_xref="HGNC:HGNC:1773"
/db_xref="MIM:123829"
/translation="MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGG
GGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT
YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFG
LARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNS
EADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEML
TFNPHKRISAFRALQHSYLHKDEGNPE"
BASE COUNT 307 a 365 c 358 g 331 t
ORIGIN
1 gtctatggtc gggccctctg cgtccagctg ctccggaccg agctcgggtg tatggggccg
61 taggaaccgg ctccggggcc ccgataacgg gccgccccca cagcaccccg ggctggcgtg
121 agggtctccc ttgatctgag aatggctacc tctcgatatg agccagtggc tgaaattggt
181 gtcggtgcct atgggacagt gtacaaggcc cgtgatcccc acagtggcca ctttgtggcc
241 ctcaagagtg tgagagtccc caatggagga ggaggtggag gaggccttcc catcagcaca
301 gttcgtgagg tggctttact gaggcgactg gaggcttttg agcatcccaa tgttgtccgg
361 ctgatggacg tctgtgccac atcccgaact gaccgggaga tcaaggtaac cctggtgttt
421 gagcatgtag accaggacct aaggacatat ctggacaagg cacccccacc aggcttgcca
481 gccgaaacga tcaaggatct gatgcgccag tttctaagag gcctagattt ccttcatgcc
541 aattgcatcg ttcaccgaga tctgaagcca gagaacattc tggtgacaag tggtggaaca
601 gtcaagctgg ctgactttgg cctggccaga atctacagct accagatggc acttacaccc
661 gtggttgtta cactctggta ccgagctccc gaagttcttc tgcagtccac atatgcaaca
721 cctgtggaca tgtggagtgt tggctgtatc tttgcagaga tgtttcgtcg aaagcctctc
781 ttctgtggaa actctgaagc cgaccagttg ggcaaaatct ttgacctgat tgggctgcct
841 ccagaggatg actggcctcg agatgtatcc ctgccccgtg gagcctttcc ccccagaggg
901 ccccgcccag tgcagtcggt ggtacctgag atggaggagt cgggagcaca gctgctgctg
961 gaaatgctga cttttaaccc acacaagcga atctctgcct ttcgagctct gcagcactct
1021 tatctacata aggatgaagg taatccggag tgagcaatgg agtggctgcc atggaaggaa
1081 gaaaagctgc catttccctt ctggacactg agagggcaat ctttgccttt atctctgagg
1141 ctatggaggg tcctcctcca tctttctaca gagattactt tgctgcctta atgacattcc
1201 cctcccacct ctccttttga ggcttctcct tctccttccc atttctctac actaaggggt
1261 atgttccctc ttgtcccttt ccctaccttt atatttgggg tcctttttta tacaggaaaa
1321 acaaaacaaa gaaataatgg tcaaaaaaaa aaaaaaaaaa a
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