LOCUS BC009534 1553 bp mRNA linear HUM 30-SEP-2003
DEFINITION Homo sapiens PTEN induced putative kinase 1, mRNA (cDNA clone
IMAGE:3891886), partial cds.
ACCESSION BC009534
VERSION BC009534.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1553)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1553)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (29-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: f Column: 19.
FEATURES Location/Qualifiers
source 1..1553
/db_xref="H-InvDB:HIT000087310"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3891886"
/tissue_type="Lung, carcinoma, large cell
undifferentiated."
/clone_lib="NIH_MGC_69"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1553
/gene="PINK1"
/gene_synonym="BRPK"
/db_xref="GeneID:65018"
CDS <1..913
/gene="PINK1"
/gene_synonym="BRPK"
/codon_start=2
/product="PINK1 protein"
/protein_id="AAH09534.1"
/db_xref="GeneID:65018"
/translation="RAFTSSVPLLPGALVDYPDVLPSRLHPEGLGHGRTLFLVMKNYP
CTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWL
VIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWA
VGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASK
RPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLLANRLTEKCCVETKM
KMLFLANLECETLCQAALLLCSWRAAL"
misc_feature 95..670
/gene="PINK1"
/gene_synonym="BRPK"
/note="S_TKc; Region: Serine/Threonine protein kinases,
catalytic domain"
/db_xref="CDD:smart00220"
BASE COUNT 357 a 407 c 453 g 336 t
ORIGIN
1 ccgcgccttc acctcttccg tgccgctgct gccaggggcc ctggtcgact accctgatgt
61 gctgccctca cgcctccacc ctgaaggcct gggccatggc cggacgctgt tcctcgttat
121 gaagaactat ccctgtaccc tgcgccagta cctttgtgtg aacacaccca gcccccgcct
181 cgccgccatg atgctgctgc agctgctgga aggcgtggac catctggttc aacagggcat
241 cgcgcacaga gacctgaaat ccgacaacat ccttgtggag ctggacccag acggctgccc
301 ctggctggtg atcgcagatt ttggctgctg cctggctgat gagagcatcg gcctgcagtt
361 gcccttcagc agctggtacg tggatcgggg cggaaacggc tgtctgatgg ccccagaggt
421 gtccacggcc cgtcctggcc ccagggcagt gattgactac agcaaggctg atgcctgggc
481 agtgggagcc atcgcctatg aaatcttcgg gcttgtcaat cccttctacg gccagggcaa
541 ggcccacctt gaaagccgca gctaccaaga ggctcagcta cctgcactgc ccgagtcagt
601 gcctccagac gtgagacagt tggtgagggc actgctccag cgagaggcca gcaagagacc
661 atctgcccga gtagccgcaa atgtgcttca tctaagcctc tggggtgaac atattctagc
721 cctgaagaat ctgaagttag acaagatggt tggctggctc ctccaacaat cggccgccac
781 tttgttggcc aacaggctca cagagaagtg ttgtgtggaa acaaaaatga agatgctctt
841 tctggctaac ctggagtgtg aaacgctctg ccaggcagcc ctcctcctct gctcatggag
901 ggcagccctg tgatgtccct gcatggagct ggtgaattac taaaagaact tggcatcctc
961 tgtgtcgtga tggtctgtga atggtgaggg tgggagtcag gagacaagac agcgcagaga
1021 gggctggtta gccggaaaag gcctcgggct tggcaaatgg aagaacttga gtgagagttc
1081 agtctgcagt cctgtgctca cagacatctg aaaagtgaat ggccaagctg gtctagtaga
1141 tgaggctgga ctgaggaggg gtaggcctgc atccacatag aggatccagg ccaaggcact
1201 ggctgtcagt ggcagagttt ggctgtgacc tttgccccta acacgaggaa ctcgtttgaa
1261 gggggcagcg tagcatgtct gatttgccac ctggatgaag gcagacatca acatgggtca
1321 gcacgttgag ttacgggagt gggaaattac atgaggcctg ggcctctgcg ttcccaagct
1381 gtgcgttctg gaccagctac tgaattatta atctcactta gcgaaagtga cggatgagca
1441 gtaagtaagt aagtgtgggg atttaaactt gagggtttcc ctcctgacta gcctctctta
1501 caggaattgt gaaatattaa atgcaaattt acaactgcaa aaaaaaaaaa aaa
//