LOCUS BC009460 1525 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens kelch domain containing 3, mRNA (cDNA clone MGC:15936
IMAGE:3537223), complete cds.
ACCESSION BC009460
VERSION BC009460.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1525)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1525)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (19-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 23 Row: j Column: 2.
FEATURES Location/Qualifiers
source 1..1525
/db_xref="H-InvDB:HIT000034378"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15936 IMAGE:3537223"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1525
/gene="KLHDC3"
/gene_synonym="dJ20C7.3"
/gene_synonym="HPEAS"
/gene_synonym="PEAS"
/db_xref="GeneID:116138"
CDS 154..1323
/gene="KLHDC3"
/gene_synonym="dJ20C7.3"
/gene_synonym="HPEAS"
/gene_synonym="PEAS"
/codon_start=1
/product="KLHDC3 protein"
/protein_id="AAH09460.1"
/db_xref="GeneID:116138"
/translation="MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQI
DVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGAC
NVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKL
DTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRV
FDTRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSF
TWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDF
SPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTNSNISRPIVSSPFAYSLPSA"
misc_feature 190..336
/gene="KLHDC3"
/gene_synonym="dJ20C7.3"
/gene_synonym="HPEAS"
/gene_synonym="PEAS"
/note="kelch; Region: A beta propeller domain involved in
protein-protein interactions and some enzymatic actvities
like gycolate oxidase"
/db_xref="CDD:LOAD_kelch"
misc_feature 532..663
/gene="KLHDC3"
/gene_synonym="dJ20C7.3"
/gene_synonym="HPEAS"
/gene_synonym="PEAS"
/note="kelch; Region: A beta propeller domain involved in
protein-protein interactions and some enzymatic actvities
like gycolate oxidase"
/db_xref="CDD:LOAD_kelch"
misc_feature 679..996
/gene="KLHDC3"
/gene_synonym="dJ20C7.3"
/gene_synonym="HPEAS"
/gene_synonym="PEAS"
/note="COG3055; Region: Uncharacterized protein conserved
in bacteria [Function unknown]"
/db_xref="CDD:COG3055"
BASE COUNT 341 a 407 c 421 g 356 t
ORIGIN
1 ctcgttgggg actaaggcgt cggttggcgc gcaacgggtt ctaggctgca ggcagctcga
61 ggacccgcgg ccccgccccg gctcggcctg gcagatagca gaggcagcag gccgtgccgg
121 gggggcatgt tgctgtaacc agtggcccag gggatgttac ggtggacagt gcacctggag
181 ggcgggcccc gcagggtgaa ccatgctgca gtggctgtcg ggcatcgggt atactccttc
241 gggggttact gctctggtga agactatgag acactgcgtc agatagatgt gcacattttc
301 aatgcagtgt ccttgcgttg gacaaagctg cccccggtga agtctgccat ccgtgggcaa
361 gctcctgtgg taccctacat gcgctatgga cactcaaccg tcctcatcga cgacacagtc
421 ctcctttggg gcgggcggaa tgacaccgaa ggggcctgca atgtgctcta tgcctttgac
481 gtcaatacgc acaagtggtt cacaccccga gtgtcaggga cagttcctgg ggcccgggat
541 ggacattcag cctgtgtcct aggcaagatc atgtacattt ttgggggcta cgagcagcag
601 gcggactgtt tttccaatga cattcacaag ctagatacca gcaccatgac atggactctt
661 atctgtacaa agggcagccc tgcacgctgg agggacttcc actcagccac aatgctggga
721 agtcacatgt atgtctttgg gggccgtgcc gaccgctttg ggccattcca ttccaacaat
781 gagatttact gcaaccgcat tcgagtcttt gacaccagaa ctgaggcttg gctggactgt
841 cccccgactc cagtgctgcc tgaggggcgc cggagccact cggcctttgg ctacaatggg
901 gagctgtaca tctttggtgg ttataatgca aggctgaacc ggcacttcca tgacctctgg
961 aagtttaatc ctgtgtcctt tacctggaaa aagattgaac cgaaggggaa ggggccatgt
1021 ccccgccggc gccagtgctg ctgtattgtt ggtgacaaga ttgtcctctt tgggggtacc
1081 agtccatctc ctgaggaagg cctgggagat gaatttgacc ttatagatca ttctgactta
1141 cacattttgg actttagccc tagtctgaag actctgtgca aactggccgt gattcagtat
1201 aacctagacc agtcctgttt gcctcatgat atcaggtggg agctgaatgc catgaccacc
1261 aacagcaata tcagtcgccc catcgtctcc tccccctttg cctattccct cccctctgct
1321 tgagccttga gccttgactg ggagctgaaa ggagttgcag ctgttggcat gagacctcct
1381 tctccccgtc ttggggaggt ggggaccagc agataaatcc cacccttcct tgagctgtcg
1441 ctgtactctg aagttcagcc agctcagatt ttataaaaat taattaaaat ctccaaaaaa
1501 aaaaaaaaaa aaaaaaaaaa aaaaa
//