LOCUS BC009397 1607 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens prostaglandin E synthase 2, mRNA (cDNA clone
IMAGE:4134979), partial cds.
ACCESSION BC009397
VERSION BC009397.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1607)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1607)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC009397.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: l Column: 15.
FEATURES Location/Qualifiers
source 1..1607
/db_xref="H-InvDB:HIT000087269"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4134979"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1607
/gene="PTGES2"
/gene_synonym="C9orf15"
/gene_synonym="FLJ14038"
/gene_synonym="GBF-1"
/gene_synonym="GBF1"
/db_xref="GeneID:80142"
CDS <1..1114
/gene="PTGES2"
/gene_synonym="C9orf15"
/gene_synonym="FLJ14038"
/gene_synonym="GBF-1"
/gene_synonym="GBF1"
/codon_start=2
/product="PTGES2 protein"
/protein_id="AAH09397.2"
/db_xref="GeneID:80142"
/translation="VRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAA
RKGSPRLLGAAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKT
CPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSV
IISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGK
EARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGA
AAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH"
misc_feature 287..706
/gene="PTGES2"
/gene_synonym="C9orf15"
/gene_synonym="FLJ14038"
/gene_synonym="GBF-1"
/gene_synonym="GBF1"
/note="Gst; Region: Glutathione S-transferase
[Posttranslational modification, protein turnover,
chaperones]"
/db_xref="CDD:COG0625"
misc_feature 812..1081
/gene="PTGES2"
/gene_synonym="C9orf15"
/gene_synonym="FLJ14038"
/gene_synonym="GBF-1"
/gene_synonym="GBF1"
/note="GST_C; Region: Glutathione S-transferase,
C-terminal domain. Function: conjugation of reduced
glutathione to a variety of targets. Also included in the
alignment, but are not GSTs: * S-crystallins from squid.
Similarity to GST previously noted. * Eukaryotic
elongation factors 1-gamma. Not known to have GST
activity"
/db_xref="CDD:pfam00043"
BASE COUNT 318 a 494 c 519 g 276 t
ORIGIN
1 ggtgcgggcg ctgtggcctg gtgggtgcgc cttggcctgg aggctgggag gccgccccca
61 gccgctgcta cccacgcaga gccgggctgg cttcgcgggg gcggcgggcg gcccgagccc
121 cgtggctgca gctcgtaagg ggagcccgcg gctgctggga gctgcggcgc tggccctggg
181 gggagccctg gggctgtacc acacggcgcg gtggcacctg cgcgcccagg acctccacgc
241 agagcgctca gccgcgcagc tctccctgtc cagccgcctg cagctgaccc tgtaccagta
301 caagacgtgt cccttctgca gcaaggtccg agccttcctc gacttccatg ccctgcccta
361 ccaggtggtg gaggtgaacc ctgtgcgcag ggctgagatc aagttctcct cctacagaaa
421 ggtgcccatc ctggtggccc aggaaggaga aagctcgcaa caactaaatg actcctctgt
481 catcatcagc gccctcaaga cctacctggt gtcggggcag cccctggaag agatcatcac
541 ctactaccca gccatgaagg ctgtgaacga gcagggcaag gaggtgaccg agttcggcaa
601 taagtactgg ctcatgctca acgagaagga ggcccagcaa gtgtatggtg ggaaggaggc
661 caggacggag gagatgaagt ggcggcagtg ggcggacgac tggctggtgc acctgatctc
721 ccccaatgtg taccgcacgc ccaccgaggc tctggcgtcc tttgactaca ttgtccgcga
781 gggcaagttc ggagccgtgg agggtgccgt ggccaagtac atgggtgcag cggccatgta
841 cctcatcagc aagcgactca agagcaggca ccgcctccag gacaacgtgc gcgaggacct
901 ctatgaggct gctgacaagt gggtggctgc tgtgggcaag gaccggccct tcatgggggg
961 ccagaagccg aatctcgctg atttggcggt gtatggcgtg ctgcgtgtga tggaggggct
1021 ggatgcattc gatgacctga tgcagcacac gcacatccag ccctggtacc tgcgggtgga
1081 gagggccatc accgaggcct ccccagcgca ctgaatgtcc ccgcgcagag cagagggaag
1141 gcagcggaag acgccagctg ccagggcctg gggccactgg gccagcgcct ggcgatactg
1201 gttgggggca ggatcattct gccccttgtc cacgcacccc caccagccct ctcgcttcta
1261 acacagggca cctgctgggg ctcagggatg ttagggacga gttccagccc tgccactgcc
1321 ctggggcgac ccctccctgt ccctgcctcc ctgctctgcc gcccctcttc ctggaccctc
1381 agtggctgtc ccatggctac atcctgtggg tgggggccct cgacaggaca gcaggacggt
1441 ttgttttcag tggaatccca tccctgggtt cccctggttc ccactcttcc caagcctccc
1501 gggactggga catgtttgca ataaaggaaa ggtttgtggc gcctgtcatg gcaggcatct
1561 catggaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//